Arachidic acid is a lipid of Fatty Acyls (FA) class. Arachidic acid is associated with abnormalities such as nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Cardiovascular Diseases. The involved functions are known as Process, Regulation, Saturated, Oxidation and enzyme activity. Arachidic acid often locates in Mitochondria, Brown Fat, Microsomes, Membrane and Muscle. The associated genes with Arachidic acid are ELOVL3 gene, P4HTM gene, CFLAR gene, Homologous Gene and Polypeptides. The related lipids are Fatty Acids, Glycerophospholipids, Palmitates, Stearic acid and hexadecenoic acid.
To understand associated biological information of Arachidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Arachidic acid is suspected in Diabetes, Hypertensive disease, nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Arachidic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Arnold-Chiari Malformation | D001139 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Brophy PJ and Vance DE | The synthesis and hydrolysis of long-chain fatty acyl-coenzyme A thioesters by soluble and microsomal fractions from the brain of the developing rat. | 1976 | Biochem. J. | pmid:1008855 |
| Almeida T et al. | Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus. | 1999 | Brain Res. | pmid:10216201 |
| Sato K et al. | Apatite formation on organic monolayers in simulated body environment. | 2000 | J. Biomed. Mater. Res. | pmid:10644958 |
| Reason M et al. | Characterisation of fatty acid multilayers using a TSM biosensor. | 2000 | Int J Pharm | pmid:10675678 |
| Cronan JE et al. | Regulation of membrane lipid synthesis in Escherichia coli. Accumulation of free fatty acids of abnormal length during inhibition of phospholipid synthesis. | 1975 | J. Biol. Chem. | pmid:1097444 |
| Cahoon EB et al. | Production of fatty acid components of meadowfoam oil in somatic soybean embryos. | 2000 | Plant Physiol. | pmid:10982439 |
| Gole A et al. | Fabrication, characterization, and enzymatic activity of encapsulated fungal protease--fatty lipid biocomposite films. | 2000 | Anal. Chem. | pmid:11008764 |
| Ito H et al. | [Some observations on prognosis in congenital hydrocephalus (second report) -with reference to the physical handicap in survival cases (author's transl)]. | 1975 | No Shinkei Geka | pmid:1107877 |
| Li D | Relationship between the concentrations of plasma phospholipid stearic acid and plasma lipoprotein lipids in healthy men. | 2001 | Clin. Sci. | pmid:11115414 |
| Sakata T et al. | Structural elucidation of twelve novel esters composed of five fatty acids and three new branched alcohols together with four monoterpenoids from Sancassania shanghaiensis (Acari: Acaridae). | 2001 | Biosci. Biotechnol. Biochem. | pmid:11388473 |
| He H et al. | The effect of temperature on the fatty acids and isozymes of a psychrotrophic and two mesophilic species of Xenorhabdus, a bacterial symbiont of entomopathogenic nematodes. | 2001 | Can. J. Microbiol. | pmid:11400727 |
| Constantino C et al. | Surface enhanced resonance Raman scattering imaging of Langmuir-Blodgett monolayers of bis (benzimidazo) thioperylene. | 2001 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:11419467 |
| Takamoto DY et al. | Stable ordering in Langmuir-Blodgett films. | 2001 | Science | pmid:11509723 |
| Ballistreri A et al. | Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids. | 2001 | Int. J. Biol. Macromol. | pmid:11518582 |
| Mancuso P et al. | Evaluation of phagocytosis and arachidonate metabolism by alveolar macrophages and recruited neutrophils from F344xBN rats of different ages. | 2001 | Mech. Ageing Dev. | pmid:11557288 |
| Hlongwane C et al. | Comparative quantitative fatty acid analysis of triacylglycerols using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and gas chromatography. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11675670 |
| Schewe T et al. | Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase. | 2001 | Biol. Chem. | pmid:11843182 |
| Wanten GJ et al. | Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. | 2002 | Eur. J. Clin. Invest. | pmid:11952815 |
| Egea PF et al. | Molecular recognition of agonist ligands by RXRs. | 2002 | Mol. Endocrinol. | pmid:11981034 |
| Pozzi R et al. | Inflammatory mediators induced by coarse (PM2.5-10) and fine (PM2.5) urban air particles in RAW 264.7 cells. | 2003 | Toxicology | pmid:12504355 |
| Fernández-Moya V et al. | Temperature-related non-homogeneous fatty acid desaturation in sunflower (Helianthus annuus L.) seeds. | 2003 | Planta | pmid:12624771 |
| Buckner JS and Hagen MM | Triacylglycerol and phospholipid fatty acids of the silverleaf whitefly: composition and biosynthesis. | 2003 | Arch. Insect Biochem. Physiol. | pmid:12761874 |
| Riebeling C et al. | Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. | 2003 | J. Biol. Chem. | pmid:12912983 |
| GOERANSSON G | THE METABOLISM OF FATTY ACIDS IN THE RAT. 3. ARACHIDIC ACID. | 1965 | Acta Physiol. Scand. | pmid:14329153 |
| Anwar F and Bhanger MI | Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan. | 2003 | J. Agric. Food Chem. | pmid:14558778 |
| Chen N et al. | Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. | 2003 | Eur. J. Pharmacol. | pmid:14575792 |
| Chavez JA and Summers SA | Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. | 2003 | Arch. Biochem. Biophys. | pmid:14592453 |
| Kulacoglu DN et al. | Alterations of fatty acid composition of erythrocyte membrane in type 2 diabetes patients with diabetic retinopathy. | Jpn. J. Ophthalmol. | pmid:14636844 | |
| Sun GY et al. | Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases. | 2004 | J. Lipid Res. | pmid:14657205 |
| Constantino CJ et al. | Surface-enhanced resonance raman scattering: single-molecule detection in a Langmuir-Blodgett monolayer. | 2003 | Appl Spectrosc | pmid:14658697 |
| O'Dowd YM et al. | Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated respiratory burst in human neutrophils by adrenaline: inhibition of Phospholipase A2 activity but not p47phox phosphorylation and translocation. | 2004 | Biochem. Pharmacol. | pmid:14667941 |
| Barbarich NC et al. | Use of nutritional supplements to increase the efficacy of fluoxetine in the treatment of anorexia nervosa. | 2004 | Int J Eat Disord | pmid:14705152 |
| Costa AS and Imae T | Morphological investigation of hybrid Langmuir-Blodgett films of arachidic acid with a hydrotalcite/dendrimer nanocomposite. | 2004 | Langmuir | pmid:15379519 |
| Hunt AN et al. | Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha. | 2004 | Biochim. Biophys. Acta | pmid:15522822 |
| de Jong AE et al. | Behavior of Clostridium perfringens at low temperatures. | 2004 | Int. J. Food Microbiol. | pmid:15527920 |
| Rupp H et al. | Risk stratification by the "EPA+DHA level" and the "EPA/AA ratio" focus on anti-inflammatory and antiarrhythmogenic effects of long-chain omega-3 fatty acids. | 2004 | Herz | pmid:15580322 |
| Kuroda S | J-aggregation and its characterization in Langmuir-Blodgett films of merocyanine dyes. | 2004 | Adv Colloid Interface Sci | pmid:15589808 |
| Chen D et al. | Particle-rod hybrids: growth of arachidic acid molecular rods from capped cadmium selenide nanoparticles. | 2004 | J. Am. Chem. Soc. | pmid:15600308 |
| Fernández-Real JM et al. | Circulating adiponectin and plasma fatty acid profile. | 2005 | Clin. Chem. | pmid:15637134 |
| Diaz ME et al. | Infrared spectroscopy analysis of the structure of multilayer Langmuir-Blodgett films: effect of deposition velocity and pH. | 2005 | Langmuir | pmid:15641830 |
| Ghosh D et al. | Transcription of T7 DNA immobilised on latex beads and Langmuir-Blodgett film. | 2005 | J. Biochem. Biophys. Methods | pmid:15656943 |
| Perona JS and Ruiz-Gutierrez V | Triacylglycerol molecular species are depleted to different extents in the myocardium of spontaneously hypertensive rats fed two oleic acid-rich oils. | 2005 | Am. J. Hypertens. | pmid:15691620 |
| Salas JJ et al. | Very long chain fatty acid synthesis in sunflower kernels. | 2005 | J. Agric. Food Chem. | pmid:15796615 |
| Shchipunov YA et al. | Polysaccharides as a template for silicate generated by sol-gel processes. | 2005 | J Colloid Interface Sci | pmid:15837474 |
| Vitta S | Metal-substituted organic Cd-arachidate multilayers as soft-x-ray mirrors. | 2005 | Appl Opt | pmid:15943259 |
| Hagfors L et al. | Fat intake and composition of fatty acids in serum phospholipids in a randomized, controlled, Mediterranean dietary intervention study on patients with rheumatoid arthritis. | 2005 | Nutr Metab (Lond) | pmid:16216119 |
| Zou G et al. | Study of molecular interaction in the mixed film of arachidic acid and metal beta-diketonate complexes by the "surface ions" method. | 2003 | J Colloid Interface Sci | pmid:16256550 |
| Brar LK et al. | Langmuir monolayer as a tool toward visualization of a specific DNA-protein complex. | 2005 | Langmuir | pmid:16262335 |
| Erriquez J et al. | Calcium signals activated by arachidonic acid in embryonic chick ciliary ganglion neurons. | 2005 | Neurosignals | pmid:16301839 |
| Westerberg R et al. | ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue. | 2006 | J. Biol. Chem. | pmid:16326704 |
| Chen CW and Liu TJ | Maximum withdrawal speed for Langmuir-Blodgett film deposition of arachidic acid. | 2006 | J Colloid Interface Sci | pmid:16403506 |
| Botto L et al. | Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema. | 2006 | Respir. Res. | pmid:16412226 |
| Zhao J et al. | Simultaneous determination of saponins and fatty acids in Ziziphus jujuba (Suanzaoren) by high performance liquid chromatography-evaporative light scattering detection and pressurized liquid extraction. | 2006 | J Chromatogr A | pmid:16458908 |
| Bhaumik A et al. | Formation of a DNA layer on Langmuir-Blodgett films and its enzymatic digestion. | 2004 | Langmuir | pmid:16459606 |
| Beattie DA et al. | Sum-frequency spectroscopy of a monolayer of zinc arachidate at the solid-solid interface. | 2006 | J Phys Chem B | pmid:16471815 |
| Valli L et al. | Ethane-bridged zinc porphyrin dimers in Langmuir-Shäfer thin films: structural and spectroscopic properties. | 2006 | J Phys Chem B | pmid:16526704 |
| Duan W and Zhang L | Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16618538 |
| Holman J et al. | Sum frequency generation from Langmuir-Blodgett multilayer films on metal and dielectric substrates. | 2005 | J Phys Chem B | pmid:16853409 |
| Vecino AM et al. | Phospholipase A2 activity in platelets of patients with primary thrombocythemia. | 2006 | Platelets | pmid:16928606 |
| Eto K et al. | Modulation of ATP-induced inward currents by docosahexaenoic acid and other fatty acids in rat nodose ganglion neurons. | 2006 | J. Pharmacol. Sci. | pmid:17099292 |
| Sawant SN et al. | Polymer-surfactant layered heterostructures by electropolymerization of phenosafranine in Langmuir-Blodgett films. | 2006 | J Phys Chem B | pmid:17134212 |
| Yao S et al. | Preparative isolation and purification of chemical constituents from the root of Adenophora tetraphlla by high-speed counter-current chromatography with evaporative light scattering detection. | 2007 | J Chromatogr A | pmid:17150224 |
| Yao K et al. | Expression of the Arabidopsis ADS1 gene in Brassica juncea results in a decreased level of total saturated fatty acids. | 2003 | Plant Biotechnol. J. | pmid:17156034 |
| Teshima R et al. | Effects of polyunsaturated fatty acids on calcium response and degranulation from RBL-2H3 cells. | 2007 | Int. Immunopharmacol. | pmid:17178388 |
| Salles HC et al. | The venomous secrets of the web droplets from the viscid spiral of the orb-weaver spider Nephila clavipes (Araneae, Tetragnatidae). | 2006 | Chem. Biodivers. | pmid:17193305 |
| Johansson AS et al. | Docosahexaenoic acid stabilizes soluble amyloid-beta protofibrils and sustains amyloid-beta-induced neurotoxicity in vitro. | 2007 | FEBS J. | pmid:17227385 |
| Vaknin D et al. | Ordering by collapse: formation of bilayer and trilayer crystals by folding Langmuir monolayers. | 2007 | Langmuir | pmid:17279671 |
| Rajdev P and Chatterji D | Thermodynamic and spectroscopic studies on the nickel arachidate-RNA polymerase Langmuir-Blodgett monolayer. | 2007 | Langmuir | pmid:17279692 |
| Wei T et al. | DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids. | 2007 | BMC Womens Health | pmid:17407572 |
| Chêne G et al. | n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells. | 2007 | Biochim. Biophys. Acta | pmid:17459764 |
| Hirano Y et al. | Thermal behavior of J-aggregates in mixed Langmuir-Blodgett films composed of merocyanine dye and deuterated arachidic acid investigated by UV-visible and infrared absorption spectroscopy. | 2007 | Langmuir | pmid:17530788 |
| Dong J et al. | Crystallization of silver carboxylates from sodium carboxylate mixtures. | 2007 | Langmuir | pmid:17567157 |
| Bala T et al. | Interaction of different metal ions with carboxylic acid group: a quantitative study. | 2007 | J Phys Chem A | pmid:17585841 |
| McMullen RL and Kelty SP | Molecular dynamic simulations of eicosanoic acid and 18-methyleicosanoic acid langmuir monolayers. | 2007 | J Phys Chem B | pmid:17718471 |
| Qaqish SE and Paige MF | Mechanistic insight into domain formation and growth in a phase-separated Langmuir-Blodgett monolayer. | 2007 | Langmuir | pmid:17727296 |
| Kusunoki M et al. | Relationship between serum concentrations of saturated fatty acids and unsaturated fatty acids and the homeostasis model insulin resistance index in Japanese patients with type 2 diabetes mellitus. | 2007 | J. Med. Invest. | pmid:17878672 |
| Gakwaya R et al. | Examining the collision-induced decomposition spectra of ammoniated triglycerides. III. The linoleate and arachidonate series. | 2007 | Rapid Commun. Mass Spectrom. | pmid:17893948 |
| Wang J et al. | Study of assembly of arachidic acid/LDHs hybrid films containing photoactive dyes. | 2008 | J Colloid Interface Sci | pmid:18036601 |
| Sabin MA et al. | Fasting nonesterified fatty acid profiles in childhood and their relationship with adiposity, insulin sensitivity, and lipid levels. | 2007 | Pediatrics | pmid:18055661 |
| Odabasi E et al. | Lipophilic components of different therapeutic mud species. | 2007 | J Altern Complement Med | pmid:18166123 |
| Leikin-Frenkel A et al. | Hypocholesterolemic effects of fatty acid bile acid conjugates (FABACs) in mice. | 2008 | Arch. Biochem. Biophys. | pmid:18167305 |
| Koletzko B et al. | The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. | 2008 | J Perinat Med | pmid:18184094 |
| Geronikaki A et al. | Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents. | 2007 | Bioinorg Chem Appl | pmid:18256725 |
| Kang ST and Ahn H | Dicyanopyrazine-linked porphyrin Langmuir-Blodgett films. | 2008 | J Colloid Interface Sci | pmid:18262539 |
| Hirano Y et al. | Conversion of the aggregation state of merocyanine dye, modification of the subcell packing of arachidic acid, and removal of the majority of n-octadecane by hydrothermal treatment in the liquid phase in a mixed Langmuir-Blodgett film of the ternary system. | 2008 | Langmuir | pmid:18288876 |
| Zheng L et al. | Chemically alternating Langmuir-Blodgett thin films as a model for molecular depth profiling by mass spectrometry. | 2008 | J. Am. Soc. Mass Spectrom. | pmid:18293488 |
| Mandal P et al. | Orange-red luminescence from Cu doped CdS nanophosphor prepared using mixed Langmuir-Blodgett multilayers. | 2008 | J Chem Phys | pmid:18361597 |
| Lombardi A et al. | Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle. | 2008 Jul-Aug | Biochim. Biophys. Acta | pmid:18471434 |
| Basit H et al. | Two-component hydrogels comprising fatty acids and amines: structure, properties, and application as a template for the synthesis of metal nanoparticles. | 2008 | Chemistry | pmid:18537217 |
| Maidul Islam AK and Mukherjee M | Characterization of Langmuir-Blodgett film using differential charging in X-ray photoelectron spectroscopy. | 2008 | J Phys Chem B | pmid:18582103 |
| Bonham MP et al. | Habitual fish consumption does not prevent a decrease in LCPUFA status in pregnant women (the Seychelles Child Development Nutrition Study). | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18585023 |
| Qaqish SE and Paige MF | Characterization of domain growth kinetics in a mixed perfluorocarbon-hydrocarbon Langmuir-Blodgett monolayer. | 2008 | J Colloid Interface Sci | pmid:18597763 |
| Jüttner B et al. | Unsaturated long-chain fatty acids induce the respiratory burst of human neutrophils and monocytes in whole blood. | 2008 | Nutr Metab (Lond) | pmid:18625045 |
| Lasserre R et al. | Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation. | 2008 | Nat. Chem. Biol. | pmid:18641634 |
| Leitenberger W et al. | Application of a pnCCD in X-ray diffraction: a three-dimensional X-ray detector. | 2008 | J Synchrotron Radiat | pmid:18728315 |
| Zheng L et al. | Depth resolution during C60+ profiling of multilayer molecular films. | 2008 | Anal. Chem. | pmid:18778034 |
| Rubin-Pitel SB et al. | Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa. | 2008 | Chem. Biol. | pmid:18940668 |
| Hirano Y et al. | Thermal behavior of H-aggregate in a mixed Langmuir-Blodgett film of merocyanine dye, arachidic acid, and n-octadecane ternary system investigated by UV-visible and IR absorption spectroscopy. | 2008 | J Phys Chem B | pmid:18942872 |
| Livanec PW and Dunn RC | Single-molecule probes of lipid membrane structure. | 2008 | Langmuir | pmid:19053664 |