Arachidic acid is a lipid of Fatty Acyls (FA) class. Arachidic acid is associated with abnormalities such as nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Cardiovascular Diseases. The involved functions are known as Process, Regulation, Saturated, Oxidation and enzyme activity. Arachidic acid often locates in Mitochondria, Brown Fat, Microsomes, Membrane and Muscle. The associated genes with Arachidic acid are ELOVL3 gene, P4HTM gene, CFLAR gene, Homologous Gene and Polypeptides. The related lipids are Fatty Acids, Glycerophospholipids, Palmitates, Stearic acid and hexadecenoic acid.
To understand associated biological information of Arachidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Arachidic acid is suspected in Diabetes, Hypertensive disease, nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Arachidic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Arnold-Chiari Malformation | D001139 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Vuori E et al. | Maternal diet and fatty acid pattern of breast milk. | 1982 | Acta Paediatr Scand | pmid:6897601 |
| Swidzińska K et al. | Effect of fatty acid chain length and saturation on formation of the acylenzyme complex by the isolated aortic enzyme fraction. | 1989 Mar-Apr | Acta Physiol Pol | pmid:2641424 |
| GOERANSSON G | THE METABOLISM OF FATTY ACIDS IN THE RAT. 3. ARACHIDIC ACID. | 1965 | Acta Physiol. Scand. | pmid:14329153 |
| Kuroda S | J-aggregation and its characterization in Langmuir-Blodgett films of merocyanine dyes. | 2004 | Adv Colloid Interface Sci | pmid:15589808 |
| Ebbesson SO et al. | Heart rate is associated with red blood cell fatty acid concentration: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. | 2010 | Am. Heart J. | pmid:20569715 |
| Lemaitre RN et al. | Plasma phospholipid very-long-chain saturated fatty acids and incident diabetes in older adults: the Cardiovascular Health Study. | 2015 | Am. J. Clin. Nutr. | pmid:25787996 |
| Perona JS and Ruiz-Gutierrez V | Triacylglycerol molecular species are depleted to different extents in the myocardium of spontaneously hypertensive rats fed two oleic acid-rich oils. | 2005 | Am. J. Hypertens. | pmid:15691620 |
| Vandenplas Y et al. | Safety and adequacy of a semi-elemental formula for children with gastro-intestinal disease. | 2010 | Amino Acids | pmid:19408097 |
| Laurens LM et al. | Accurate and reliable quantification of total microalgal fuel potential as fatty acid methyl esters by in situ transesterification. | 2012 | Anal Bioanal Chem | pmid:22349344 |
| Gole A et al. | Fabrication, characterization, and enzymatic activity of encapsulated fungal protease--fatty lipid biocomposite films. | 2000 | Anal. Chem. | pmid:11008764 |
| Lu C et al. | Molecular depth profiling of buried lipid bilayers using C(60)-secondary ion mass spectrometry. | 2011 | Anal. Chem. | pmid:21121691 |
| Zheng L et al. | Depth resolution during C60+ profiling of multilayer molecular films. | 2008 | Anal. Chem. | pmid:18778034 |
| Hsu WY et al. | Screening assay of very long chain fatty acids in human plasma with multiwalled carbon nanotube-based surface-assisted laser desorption/ionization mass spectrometry. | 2010 | Anal. Chem. | pmid:20704371 |
| Volkmer D et al. | Morphosynthesis of star-shaped titania-silica shells. | 2003 | Angew. Chem. Int. Ed. Engl. | pmid:19757590 |
| Vitta S | Metal-substituted organic Cd-arachidate multilayers as soft-x-ray mirrors. | 2005 | Appl Opt | pmid:15943259 |
| Constantino CJ et al. | Surface-enhanced resonance raman scattering: single-molecule detection in a Langmuir-Blodgett monolayer. | 2003 | Appl Spectrosc | pmid:14658697 |
| Sakuradani E et al. | Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19415268 |
| Villarroel M et al. | [Chemical composition and biological quality of defatted hazelnut flour]. | 1989 | Arch Latinoam Nutr | pmid:2487030 |
| Buks J et al. | Do soluble p55 and p75 TNF-α receptor concentrations play a role in women with primary sterility? | 2010 | Arch Med Sci | pmid:22371757 |
| Kiuchi K and Hager LP | Reconstitution of the lipid-depleted pyruvate oxidase system of Escherichia coli: the palmitic acid effect. | 1984 | Arch. Biochem. Biophys. | pmid:6385860 |
| Leikin-Frenkel A et al. | Hypocholesterolemic effects of fatty acid bile acid conjugates (FABACs) in mice. | 2008 | Arch. Biochem. Biophys. | pmid:18167305 |
| Chavez JA and Summers SA | Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. | 2003 | Arch. Biochem. Biophys. | pmid:14592453 |
| Buckner JS and Hagen MM | Triacylglycerol and phospholipid fatty acids of the silverleaf whitefly: composition and biosynthesis. | 2003 | Arch. Insect Biochem. Physiol. | pmid:12761874 |
| Brophy PJ and Vance DE | The synthesis and hydrolysis of long-chain fatty acyl-coenzyme A thioesters by soluble and microsomal fractions from the brain of the developing rat. | 1976 | Biochem. J. | pmid:1008855 |
| Kanoh H and Lindsay DB | Synthesis of fatty acids from (1- 14 C)acetyl-coenzyme A in subcellular particles of rat epididymal adipose tissue. | 1972 | Biochem. J. | pmid:4638795 |
| Nishikawa M et al. | Possible involvement of direct stimulation of protein kinase C by unsaturated fatty acids in platelet activation. | 1988 | Biochem. Pharmacol. | pmid:3401239 |
| O'Dowd YM et al. | Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated respiratory burst in human neutrophils by adrenaline: inhibition of Phospholipase A2 activity but not p47phox phosphorylation and translocation. | 2004 | Biochem. Pharmacol. | pmid:14667941 |
| Murate M et al. | Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane. | 2010 | Biochemistry | pmid:20433166 |
| Hunt AN et al. | Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha. | 2004 | Biochim. Biophys. Acta | pmid:15522822 |
| Chêne G et al. | n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells. | 2007 | Biochim. Biophys. Acta | pmid:17459764 |
| Lombardi A et al. | Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle. | 2008 Jul-Aug | Biochim. Biophys. Acta | pmid:18471434 |
| Stelzle M and Sackmann E | Sensitive detection of protein adsorption to supported lipid bilayers by frequency-dependent capacitance measurements and microelectrophoresis. | 1989 | Biochim. Biophys. Acta | pmid:2541788 |
| Keough KM et al. | The influence of unsaturation on the phase transition temperatures of a series of heteroacid phosphatidylcholines containing twenty-carbon chains. | 1987 | Biochim. Biophys. Acta | pmid:3111533 |
| Geronikaki A et al. | Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents. | 2007 | Bioinorg Chem Appl | pmid:18256725 |
| Schewe T et al. | Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase. | 2001 | Biol. Chem. | pmid:11843182 |
| Barnes RB et al. | Quantum yield and image contrast of bacteriochlorophyll monolayers in photoelectron microscopy. | 1978 | Biophys. J. | pmid:630040 |
| Pachence JM et al. | Location of the heme-Fe atoms within the profile structure of a monolayer of cytochrome c bound to the surface of an ultrathin lipid multilayer film. | 1989 | Biophys. J. | pmid:2550089 |
| Pachence JM and Blasie JK | The location of cytochrome c on the surface of ultrathin lipid multilayer films using x-ray diffraction. | 1987 | Biophys. J. | pmid:2827799 |
| Sakata T et al. | Structural elucidation of twelve novel esters composed of five fatty acids and three new branched alcohols together with four monoterpenoids from Sancassania shanghaiensis (Acari: Acaridae). | 2001 | Biosci. Biotechnol. Biochem. | pmid:11388473 |
| Yoneyama M et al. | Two-dimensional domain shape transitions in photosensitive monolayer assemblies. | 1995 | BioSystems | pmid:7488698 |
| Awouafack MD et al. | Antimicrobial activity and cytotoxicity of the ethanol extract, fractions and eight compounds isolated from Eriosema robustum (Fabaceae). | 2013 | BMC Complement Altern Med | pmid:24165199 |
| Waterman CL et al. | An integrated functional genomic study of acute phenobarbital exposure in the rat. | 2010 | BMC Genomics | pmid:20053287 |
| Fang X et al. | Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. | 2010 | BMC Syst Biol | pmid:21092312 |
| Wei T et al. | DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids. | 2007 | BMC Womens Health | pmid:17407572 |
| Dray F | Sensitivity and specificity of eicosanoid radioimmunoassays: new strategy. | 1983 | Br. J. Dermatol. | pmid:6860583 |
| NÃ Raghallaigh S et al. | The fatty acid profile of the skin surface lipid layer in papulopustular rosacea. | 2012 | Br. J. Dermatol. | pmid:21967555 |
| Moisés Laparra J et al. | Kojibiose ameliorates arachidic acid-induced metabolic alterations in hyperglycaemic rats. | 2015 | Br. J. Nutr. | pmid:26344377 |
| Almeida T et al. | Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus. | 1999 | Brain Res. | pmid:10216201 |
| He H et al. | The effect of temperature on the fatty acids and isozymes of a psychrotrophic and two mesophilic species of Xenorhabdus, a bacterial symbiont of entomopathogenic nematodes. | 2001 | Can. J. Microbiol. | pmid:11400727 |