Arachidic acid is a lipid of Fatty Acyls (FA) class. Arachidic acid is associated with abnormalities such as nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Cardiovascular Diseases. The involved functions are known as Process, Regulation, Saturated, Oxidation and enzyme activity. Arachidic acid often locates in Mitochondria, Brown Fat, Microsomes, Membrane and Muscle. The associated genes with Arachidic acid are ELOVL3 gene, P4HTM gene, CFLAR gene, Homologous Gene and Polypeptides. The related lipids are Fatty Acids, Glycerophospholipids, Palmitates, Stearic acid and hexadecenoic acid.
To understand associated biological information of Arachidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Arachidic acid is suspected in Diabetes, Hypertensive disease, nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Arachidic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Arnold-Chiari Malformation | D001139 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Kulacoglu DN et al. | Alterations of fatty acid composition of erythrocyte membrane in type 2 diabetes patients with diabetic retinopathy. | Jpn. J. Ophthalmol. | pmid:14636844 | |
| GOERANSSON G | THE METABOLISM OF FATTY ACIDS IN THE RAT. 3. ARACHIDIC ACID. | 1965 | Acta Physiol. Scand. | pmid:14329153 |
| Kanoh H and Lindsay DB | Synthesis of fatty acids from (1- 14 C)acetyl-coenzyme A in subcellular particles of rat epididymal adipose tissue. | 1972 | Biochem. J. | pmid:4638795 |
| Cronan JE et al. | Regulation of membrane lipid synthesis in Escherichia coli. Accumulation of free fatty acids of abnormal length during inhibition of phospholipid synthesis. | 1975 | J. Biol. Chem. | pmid:1097444 |
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| Brophy PJ and Vance DE | The synthesis and hydrolysis of long-chain fatty acyl-coenzyme A thioesters by soluble and microsomal fractions from the brain of the developing rat. | 1976 | Biochem. J. | pmid:1008855 |
| Hauser H et al. | Ion-binding to phospholipids. Interaction of calcium with phosphatidylserine. | 1976 | Eur. J. Biochem. | pmid:3416 |
| Onodera Y and Ito H | Fatty acid in cerebrospinal fluid of congenital hydrocephalus. | 1977 | Childs Brain | pmid:862460 |
| Barnes RB et al. | Quantum yield and image contrast of bacteriochlorophyll monolayers in photoelectron microscopy. | 1978 | Biophys. J. | pmid:630040 |
| Horvat RJ | Identification of some new minor acids from chicken skin lipids. | 1978 | Poult. Sci. | pmid:674060 |
| Rillema JA | Activation of guanylate cyclase by arachidonic acid in mammary gland homogenates from mice. | 1978 | Prostaglandins | pmid:30119 |
| van Joost T et al. | Sensitization to olive oil (olea europeae). | 1981 | Contact Derm. | pmid:7338030 |
| Onodera Y et al. | Fatty acid of cerebrospinal fluid in arrested hydrocephalus. | 1982 | Childs Brain | pmid:7094674 |
| Cook HW et al. | Involvement of triacylglycerol in the metabolism of fatty acids by cultured neuroblastoma and glioma cells. | 1982 | J. Lipid Res. | pmid:7161559 |
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| Kokatnur M et al. | Fatty acids of sphingomyelin from amniotic fluid of normal and diabetic pregnancies. | 1985 | Lipids | pmid:4033364 |
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| Morand O et al. | Arachidonoyl-coenzyme A synthetase and nonspecific acyl-coenzyme A synthetase activities in purified rat brain microvessels. | 1987 | J. Neurochem. | pmid:3102692 |
| Novo C et al. | Altered fatty acid membrane composition modifies lymphocyte localization in vivo. | 1987 | Cell. Immunol. | pmid:2882861 |
| Chaudhry A et al. | The effects of fatty acids on phosphoinositide synthesis and myo-inositol accumulation in exocrine pancreas. | 1987 | J. Biol. Chem. | pmid:2826420 |
| Pachence JM and Blasie JK | The location of cytochrome c on the surface of ultrathin lipid multilayer films using x-ray diffraction. | 1987 | Biophys. J. | pmid:2827799 |
| Keough KM et al. | The influence of unsaturation on the phase transition temperatures of a series of heteroacid phosphatidylcholines containing twenty-carbon chains. | 1987 | Biochim. Biophys. Acta | pmid:3111533 |
| Beaumier L et al. | Arachidonic acid-induced release of calcium in permeabilized human neutrophils. | 1987 | FEBS Lett. | pmid:3114002 |
| Nishikawa M et al. | Possible involvement of direct stimulation of protein kinase C by unsaturated fatty acids in platelet activation. | 1988 | Biochem. Pharmacol. | pmid:3401239 |
| Redgrave TG et al. | The effect of triacyl-sn-glycerol structure on the metabolism of chylomicrons and triacylglycerol-rich emulsions in the rat. | 1988 | J. Biol. Chem. | pmid:3356683 |
| Marowsky G and Steinhoff R | Hemicyanine monolayer orientation studied by second-harmonic generation. | 1988 | Opt Lett | pmid:19746010 |
| Bedzyk MJ et al. | X-ray standing waves: a molecular yardstick for biological membranes. | 1988 | Science | pmid:3175619 |
| Pachence JM et al. | Location of the heme-Fe atoms within the profile structure of a monolayer of cytochrome c bound to the surface of an ultrathin lipid multilayer film. | 1989 | Biophys. J. | pmid:2550089 |
| Stelzle M and Sackmann E | Sensitive detection of protein adsorption to supported lipid bilayers by frequency-dependent capacitance measurements and microelectrophoresis. | 1989 | Biochim. Biophys. Acta | pmid:2541788 |
| Villarroel M et al. | [Chemical composition and biological quality of defatted hazelnut flour]. | 1989 | Arch Latinoam Nutr | pmid:2487030 |
| Swidzińska K et al. | Effect of fatty acid chain length and saturation on formation of the acylenzyme complex by the isolated aortic enzyme fraction. | 1989 Mar-Apr | Acta Physiol Pol | pmid:2641424 |
| Yoneyama M et al. | Two-dimensional domain shape transitions in photosensitive monolayer assemblies. | 1995 | BioSystems | pmid:7488698 |
| Viswanathan R et al. | Liquid to hexatic to crystalline order in Langmuir-Blodgett films. | 1995 | Science | pmid:7604278 |
| Kankofer M et al. | The analysis of fatty acid content and phospholipase A2 activity in placenta of cows with and without retained fetal membranes. | 1996 | Zentralbl Veterinarmed A | pmid:8940891 |
| Almeida T et al. | Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus. | 1999 | Brain Res. | pmid:10216201 |
| Sato K et al. | Apatite formation on organic monolayers in simulated body environment. | 2000 | J. Biomed. Mater. Res. | pmid:10644958 |
| Gole A et al. | Fabrication, characterization, and enzymatic activity of encapsulated fungal protease--fatty lipid biocomposite films. | 2000 | Anal. Chem. | pmid:11008764 |
| Reason M et al. | Characterisation of fatty acid multilayers using a TSM biosensor. | 2000 | Int J Pharm | pmid:10675678 |
| Cahoon EB et al. | Production of fatty acid components of meadowfoam oil in somatic soybean embryos. | 2000 | Plant Physiol. | pmid:10982439 |