Arachidic acid is a lipid of Fatty Acyls (FA) class. Arachidic acid is associated with abnormalities such as nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Cardiovascular Diseases. The involved functions are known as Process, Regulation, Saturated, Oxidation and enzyme activity. Arachidic acid often locates in Mitochondria, Brown Fat, Microsomes, Membrane and Muscle. The associated genes with Arachidic acid are ELOVL3 gene, P4HTM gene, CFLAR gene, Homologous Gene and Polypeptides. The related lipids are Fatty Acids, Glycerophospholipids, Palmitates, Stearic acid and hexadecenoic acid.
To understand associated biological information of Arachidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Arachidic acid is suspected in Diabetes, Hypertensive disease, nervous system disorder, Liver diseases, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Arachidic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Arnold-Chiari Malformation | D001139 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hunt AN et al. | Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha. | 2004 | Biochim. Biophys. Acta | pmid:15522822 |
| Chêne G et al. | n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells. | 2007 | Biochim. Biophys. Acta | pmid:17459764 |
| Lombardi A et al. | Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle. | 2008 Jul-Aug | Biochim. Biophys. Acta | pmid:18471434 |
| Keough KM et al. | The influence of unsaturation on the phase transition temperatures of a series of heteroacid phosphatidylcholines containing twenty-carbon chains. | 1987 | Biochim. Biophys. Acta | pmid:3111533 |
| Geronikaki A et al. | Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents. | 2007 | Bioinorg Chem Appl | pmid:18256725 |
| Schewe T et al. | Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase. | 2001 | Biol. Chem. | pmid:11843182 |
| Barnes RB et al. | Quantum yield and image contrast of bacteriochlorophyll monolayers in photoelectron microscopy. | 1978 | Biophys. J. | pmid:630040 |
| Pachence JM et al. | Location of the heme-Fe atoms within the profile structure of a monolayer of cytochrome c bound to the surface of an ultrathin lipid multilayer film. | 1989 | Biophys. J. | pmid:2550089 |
| Pachence JM and Blasie JK | The location of cytochrome c on the surface of ultrathin lipid multilayer films using x-ray diffraction. | 1987 | Biophys. J. | pmid:2827799 |
| Sakata T et al. | Structural elucidation of twelve novel esters composed of five fatty acids and three new branched alcohols together with four monoterpenoids from Sancassania shanghaiensis (Acari: Acaridae). | 2001 | Biosci. Biotechnol. Biochem. | pmid:11388473 |