ANACARDIC ACID

ANACARDIC ACID is a lipid of Polyketides (PK) class.

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Current reference collection contains 568 references associated with ANACARDIC ACID in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Liu Z et al. Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene. 2013 Acta Biochim. Biophys. Sin. (Shanghai) pmid:24096006
Oliveira MS et al. Antioxidant, larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents. 2011 Acta Trop. pmid:20707981
Al-Bataineh MM et al. Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells. 2016 Am. J. Physiol. Renal Physiol. pmid:26911844
Sun Y et al. Epigenetic regulation of spinal CXCR2 signaling in incisional hypersensitivity in mice. 2013 Anesthesiology pmid:23756451
Kusio-Kobialka M et al. Inhibition of PCAF by anacardic acid derivative leads to apoptosis and breaks resistance to DNA damage in BCR-ABL-expressing cells. 2013 Anticancer Agents Med Chem pmid:23157591
Muzaffar S and Chattoo BB Apoptosis-inducing factor (Aif1) mediates anacardic acid-induced apoptosis in Saccharomyces cerevisiae. 2017 Apoptosis pmid:28012059
Harsha Raj M et al. Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer cells by the regulation of p53, MAPK and NFκβ pathways. 2016 Apoptosis pmid:26921178
Chelikani R et al. Enzymatic polymerization of natural anacardic acid and antibiofouling effects of polyanacardic acid coatings. 2009 Appl. Biochem. Biotechnol. pmid:18592408
Muzaffar S et al. Anacardic acid induces apoptosis-like cell death in the rice blast fungus Magnaporthe oryzae. 2016 Appl. Microbiol. Biotechnol. pmid:26381667
Park WJ and Ma E Inhibition of PCAF histone acetyltransferase and cytotoxic effect of N-acylanthranilic acids. 2012 Arch. Pharm. Res. pmid:22941480
Pandey D et al. SUMO1 negatively regulates reactive oxygen species production from NADPH oxidases. 2011 Arterioscler. Thromb. Vasc. Biol. pmid:21527745
Mariño G et al. Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers. 2014 Autophagy pmid:25484097
Hemshekhar M et al. Emerging roles of anacardic acid and its derivatives: a pharmacological overview. 2012 Basic Clin. Pharmacol. Toxicol. pmid:22103711
Masuoka N and Kubo I Characterization of xanthine oxidase inhibition by anacardic acids. 2004 Biochim. Biophys. Acta pmid:15062875
Toyomizu M et al. Anacardic acid-mediated changes in membrane potential and pH gradient across liposomal membranes. 2002 Biochim. Biophys. Acta pmid:11750264
Peng C et al. Alcohol-induced histone H3K9 hyperacetylation and cardiac hypertrophy are reversed by a histone acetylases inhibitor anacardic acid in developing murine hearts. 2015 Biochimie pmid:25797917
Leite Ade S et al. Evaluation of toxic, cytotoxic, mutagenic, and antimutagenic activities of natural and technical cashew nut shell liquids using the Allium cepa and Artemia salina bioassays. 2015 Biomed Res Int pmid:25861638
Luiz Gomes A et al. Anticonvulsant effect of anacardic acid in murine models: Putative role of GABAergic and antioxidant mechanisms. 2018 Biomed. Pharmacother. pmid:30170356
Wisastra R et al. Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection. 2013 Bioorg. Med. Chem. pmid:24231650
Wisastra R et al. Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases. 2012 Bioorg. Med. Chem. pmid:22789707
Ghizzoni M et al. Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. 2010 Bioorg. Med. Chem. pmid:20655754
Wu J et al. Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. 2009 Bioorg. Med. Chem. pmid:19114310
Muroi H et al. Synergistic effects of anacardic acids and methicillin against methicillin resistant Staphylococcus aureus. 2004 Bioorg. Med. Chem. pmid:14738968
Green IR et al. Molecular design of anti-MRSA agents based on the anacardic acid scaffold. 2007 Bioorg. Med. Chem. pmid:17601740
Mamidyala SK et al. Efficient synthesis of anacardic acid analogues and their antibacterial activities. 2013 Bioorg. Med. Chem. Lett. pmid:23416004
Kanojia RM et al. 6-oxa isosteres of anacardic acids as potent inhibitors of bacterial histidine protein kinase (HPK)-mediated two-component regulatory systems. 1999 Bioorg. Med. Chem. Lett. pmid:10571153
Hoellein A et al. Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma. 2014 Blood pmid:25143484
Sung B et al. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. 2008 Blood pmid:18349320
Park M et al. Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway. 2018 BMC Complement Altern Med pmid:29463243
de Souza MQ et al. Molecular evaluation of anti-inflammatory activity of phenolic lipid extracted from cashew nut shell liquid (CNSL). 2018 BMC Complement Altern Med pmid:29890972
Azad MA et al. Electrolysed reduced water decreases reactive oxygen species-induced oxidative damage to skeletal muscle and improves performance in broiler chickens exposed to medium-term chronic heat stress. 2013 Br. Poult. Sci. pmid:23815735
Jain S et al. Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival. 2012 Breast Cancer Res. Treat. pmid:22562121
George J and Kuttan R Mutagenic, carcinogenic and cocarcinogenic activity of cashewnut shell liquid. 1997 Cancer Lett. pmid:9029164
Silveira C et al. Anacardic acid from brazilian cashew nut trees reduces dentine erosion. 2014 Caries Res. pmid:24993776
Seong YA et al. Induction of the endoplasmic reticulum stress and autophagy in human lung carcinoma A549 cells by anacardic acid. 2014 Cell Biochem. Biophys. pmid:23955513
Fukuda I et al. Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. 2009 Chem. Biol. pmid:19246003
Satoh M et al. Synthesis of anacardic acids, 6-[8(Z),11(Z)-pentadecadienyl]salicylic acid and 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid. 2001 Chem. Pharm. Bull. pmid:11201219
Horibe T et al. Discovery of protein disulfide isomerase P5 inhibitors that reduce the secretion of MICA from cancer cells. 2014 Chembiochem pmid:24920482
Davidson SM et al. The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin. 2005 Chembiochem pmid:15593114
Souto JA et al. New anacardic acid-inspired benzamides: histone lysine acetyltransferase activators. 2010 ChemMedChem pmid:20683922
Souto JA et al. Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities. 2008 ChemMedChem pmid:18537201
Rajendran P et al. Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. 2011 Clin Epigenetics pmid:22247744
Diogenes MJ et al. Contact dermatitis among cashew nut workers. 1996 Contact Derm. pmid:8917839
Shilpa P et al. Anti-metastatic action of anacardic acid targets VEGF-induced signalling pathways in epithelial to mesenchymal transition. 2015 Drug Discov Ther pmid:25788052
Re A et al. Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways. 2016 Endocrine pmid:26547215
Hung CH et al. Modulation of cytokine expression in human myeloid dendritic cells by environmental endocrine-disrupting chemicals involves epigenetic regulation. 2010 Environ. Health Perspect. pmid:20056579
Cui L et al. Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development. 2008 Eukaryotic Cell pmid:18487348
Logrado LP et al. Synthesis and cytotoxicity screening of substituted isobenzofuranones designed from anacardic acids. 2010 Eur J Med Chem pmid:20537433
Chandregowda V et al. Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity. 2009 Eur J Med Chem pmid:19246131
Swamy BN et al. Synthesis of isonicotinoylhydrazones from anacardic acid and their in vitro activity against Mycobacterium smegmatis. 2007 Eur J Med Chem pmid:17112641
Green IR et al. Design and evaluation of anacardic acid derivatives as anticavity agents. 2008 Eur J Med Chem pmid:17959274
Wapenaar H et al. Enzyme kinetics and inhibition of histone acetyltransferase KAT8. 2015 Eur J Med Chem pmid:26505788
Adams JD and Garcia C Women's health among the Chumash. 2006 Evid Based Complement Alternat Med pmid:16550233
Nambiar J et al. Anacardic acid inhibits gelatinases through the regulation of Spry2, MMP-14, EMMPRIN and RECK. 2016 Exp. Cell Res. pmid:27737732
Peña AN et al. MRG15 activates the cdc2 promoter via histone acetylation in human cells. 2011 Exp. Cell Res. pmid:21324423
Zhou Q et al. Small ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor α. 2014 FEBS J. pmid:24819975
Sun Y et al. Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. 2006 FEBS Lett. pmid:16844118
Trevisan MT et al. Characterization of alkyl phenols in cashew (Anacardium occidentale) products and assay of their antioxidant capacity. 2006 Food Chem. Toxicol. pmid:16095792
Tsai YJ et al. Histone acetyltransferase p300 is induced by p38MAPK after photodynamic therapy: the therapeutic response is increased by the p300HAT inhibitor anacardic acid. 2015 Free Radic. Biol. Med. pmid:26001729
De Lima SG et al. Effects of immature cashew nut-shell liquid (Anacardium occidentale) against oxidative damage in Saccharomyces cerevisiae and inhibition of acetylcholinesterase activity. 2008 Genet. Mol. Res. pmid:18949700
Yao K et al. Anacardic acid sensitizes prostate cancer cells to radiation therapy by regulating H2AX expression. 2015 Int J Clin Exp Pathol pmid:26884865
Legut M et al. Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines - in vitro studies. 2014 Int J Nanomedicine pmid:24489469
Gnanaprakasam JNR et al. The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-κB. 2015 Int. Immunopharmacol. pmid:26371858
Seong YA et al. Anacardic acid induces mitochondrial-mediated apoptosis in the A549 human lung adenocarcinoma cells. 2013 Int. J. Oncol. pmid:23314312
Kiametis AS et al. Potential acetylcholinesterase inhibitors: molecular docking, molecular dynamics, and in silico prediction. 2017 J Mol Model pmid:28185116
Mantelingu K et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. 2007 J Phys Chem B pmid:17417897
Philip JY et al. Isolation of anacardic acid from natural cashew nut shell liquid (CNSL) using supercritical carbon dioxide. 2008 J. Agric. Food Chem. pmid:18811166
Ha TJ and Kubo I Lipoxygenase inhibitory activity of anacardic acids. 2005 J. Agric. Food Chem. pmid:15913294
Philip JY et al. Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid. 2007 J. Agric. Food Chem. pmid:17927136
Schultz DJ et al. Bioactivity of anacardic acid against colorado potato beetle (Leptinotarsa decemlineata) larvae. 2006 J. Agric. Food Chem. pmid:17002417
Kubo I et al. Antibacterial action of anacardic acids against methicillin resistant Staphylococcus aureus (MRSA). 2003 J. Agric. Food Chem. pmid:14664518
Kubo J et al. Anti-Helicobacter pylori agents from the cashew apple. 1999 J. Agric. Food Chem. pmid:10563928
Paramashivappa R et al. Synthesis of sildenafil analogues from anacardic acid and their phosphodiesterase-5 inhibition. 2002 J. Agric. Food Chem. pmid:12475293
Melo FR et al. Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells. 2017 J. Allergy Clin. Immunol. pmid:28108335
Muroi H and Kubo I Antibacterial activity of anacardic acid and totarol, alone and in combination with methicillin, against methicillin-resistant Staphylococcus aureus. 1996 J. Appl. Bacteriol. pmid:8849640
Sajeevan SE et al. Impregnation of catheters with anacardic acid from cashew nut shell prevents Staphylococcus aureus biofilm development. 2018 J. Appl. Microbiol. pmid:29972893
Kuno A et al. Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein. 2013 J. Biol. Chem. pmid:23297412
Wort SJ et al. Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites. 2009 J. Biol. Chem. pmid:19592490
Bajaj S et al. E2 Ubiquitin-conjugating Enzyme, UBE2C Gene, Is Reciprocally Regulated by Wild-type and Gain-of-Function Mutant p53. 2016 J. Biol. Chem. pmid:27129209
Hollands A et al. Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. 2016 J. Biol. Chem. pmid:27226531
Balasubramanyam K et al. Small molecule modulators of histone acetyltransferase p300. 2003 J. Biol. Chem. pmid:12624111
Shimura M et al. Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation. 2011 J. Cell Biol. pmid:21875947
Muscari C et al. Difluoromethylornithine stimulates early cardiac commitment of mesenchymal stem cells in a model of mixed culture with cardiomyocytes. 2008 J. Cell. Biochem. pmid:18240140
Radde BN et al. Anacardic Acid, Salicylic Acid, and Oleic Acid Differentially Alter Cellular Bioenergetic Function in Breast Cancer Cells. 2016 J. Cell. Biochem. pmid:26990649
Jones TH et al. 6-alkylsalicylic acids and 6-alkylresorcylic acids from ants in the genus Crematogaster from Brunei. 2005 J. Chem. Ecol. pmid:15856792
Ravnskjaer K et al. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. 2013 J. Clin. Invest. pmid:24051374
Kim MK et al. Topical application of anacardic acid (6-nonadecyl salicylic acid) reduces UV-induced histone modification, MMP-13, MMP-9, COX-2 and TNF-α expressions in hairless mice skin. 2013 J. Dermatol. Sci. pmid:23228850
Schmeck B et al. Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. 2008 J. Immunol. pmid:18606645
Kishore AH et al. Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. 2008 J. Med. Chem. pmid:18215015
Meraviglia V et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. 2015 J. Mol. Cell. Cardiol. pmid:26264759
Devipriya B and Kumaradhas P Probing the effect of intermolecular interaction and understanding the electrostatic moments of anacardic acid in the active site of p300 enzyme via DFT and charge density analysis. 2012 J. Mol. Graph. Model. pmid:22306413
Wang D et al. Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex. 1998 J. Nat. Prod. pmid:9834151
Sukumari-Ramesh S et al. Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells. 2011 J. Neurosurg. pmid:21275565
Wu Y et al. Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases signaling pathway. 2011 J. Pharmacol. Exp. Ther. pmid:21828260
Toyomizu M et al. Uncoupling effect of anacardic acids from cashew nut shell oil on oxidative phosphorylation of rat liver mitochondria. 2000 Life Sci. pmid:10665998
Peng C et al. Phenylephrine-induced cardiac hypertrophy is attenuated by a histone acetylase inhibitor anacardic acid in mice. 2017 Mol Biosyst pmid:28194469
Tedong L et al. Hydro-ethanolic extract of cashew tree (Anacardium occidentale) nut and its principal compound, anacardic acid, stimulate glucose uptake in C2C12 muscle cells. 2010 Mol Nutr Food Res pmid:20603833
Liang DY et al. The Chemokine Receptor CXCR2 Supports Nociceptive Sensitization after Traumatic Brain Injury. Mol Pain pmid:28845733
Eliseeva ED et al. Characterization of novel inhibitors of histone acetyltransferases. 2007 Mol. Cancer Ther. pmid:17876038

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