ANACARDIC ACID

ANACARDIC ACID is a lipid of Polyketides (PK) class.

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Current reference collection contains 568 references associated with ANACARDIC ACID in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Kubo J et al. Anti-Helicobacter pylori agents from the cashew apple. 1999 J. Agric. Food Chem. pmid:10563928
Kanojia RM et al. 6-oxa isosteres of anacardic acids as potent inhibitors of bacterial histidine protein kinase (HPK)-mediated two-component regulatory systems. 1999 Bioorg. Med. Chem. Lett. pmid:10571153
Toyomizu M et al. Uncoupling effect of anacardic acids from cashew nut shell oil on oxidative phosphorylation of rat liver mitochondria. 2000 Life Sci. pmid:10665998
Satoh M et al. Synthesis of anacardic acids, 6-[8(Z),11(Z)-pentadecadienyl]salicylic acid and 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid. 2001 Chem. Pharm. Bull. pmid:11201219
Toyomizu M et al. Anacardic acid-mediated changes in membrane potential and pH gradient across liposomal membranes. 2002 Biochim. Biophys. Acta pmid:11750264
Paramashivappa R et al. Synthesis of sildenafil analogues from anacardic acid and their phosphodiesterase-5 inhibition. 2002 J. Agric. Food Chem. pmid:12475293
Balasubramanyam K et al. Small molecule modulators of histone acetyltransferase p300. 2003 J. Biol. Chem. pmid:12624111
Kubo I et al. Antibacterial action of anacardic acids against methicillin resistant Staphylococcus aureus (MRSA). 2003 J. Agric. Food Chem. pmid:14664518
Muroi H et al. Synergistic effects of anacardic acids and methicillin against methicillin resistant Staphylococcus aureus. 2004 Bioorg. Med. Chem. pmid:14738968
Masuoka N and Kubo I Characterization of xanthine oxidase inhibition by anacardic acids. 2004 Biochim. Biophys. Acta pmid:15062875
Davidson SM et al. The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin. 2005 Chembiochem pmid:15593114
Jones TH et al. 6-alkylsalicylic acids and 6-alkylresorcylic acids from ants in the genus Crematogaster from Brunei. 2005 J. Chem. Ecol. pmid:15856792
Ha TJ and Kubo I Lipoxygenase inhibitory activity of anacardic acids. 2005 J. Agric. Food Chem. pmid:15913294
Trevisan MT et al. Characterization of alkyl phenols in cashew (Anacardium occidentale) products and assay of their antioxidant capacity. 2006 Food Chem. Toxicol. pmid:16095792
Adams JD and Garcia C Women's health among the Chumash. 2006 Evid Based Complement Alternat Med pmid:16550233
Sun Y et al. Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. 2006 FEBS Lett. pmid:16844118
Acevedo HR et al. Effect of 6-nonadecyl salicylic acid and its methyl ester on the induction of micronuclei in polychromatic erythrocytes in mouse peripheral blood. 2006 Mutat. Res. pmid:16857418
Schultz DJ et al. Bioactivity of anacardic acid against colorado potato beetle (Leptinotarsa decemlineata) larvae. 2006 J. Agric. Food Chem. pmid:17002417
Swamy BN et al. Synthesis of isonicotinoylhydrazones from anacardic acid and their in vitro activity against Mycobacterium smegmatis. 2007 Eur J Med Chem pmid:17112641
Mantelingu K et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. 2007 J Phys Chem B pmid:17417897
Green IR et al. Molecular design of anti-MRSA agents based on the anacardic acid scaffold. 2007 Bioorg. Med. Chem. pmid:17601740
Eliseeva ED et al. Characterization of novel inhibitors of histone acetyltransferases. 2007 Mol. Cancer Ther. pmid:17876038
Philip JY et al. Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid. 2007 J. Agric. Food Chem. pmid:17927136
Green IR et al. Design and evaluation of anacardic acid derivatives as anticavity agents. 2008 Eur J Med Chem pmid:17959274
Kishore AH et al. Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system. 2008 J. Med. Chem. pmid:18215015
Muscari C et al. Difluoromethylornithine stimulates early cardiac commitment of mesenchymal stem cells in a model of mixed culture with cardiomyocytes. 2008 J. Cell. Biochem. pmid:18240140
Sung B et al. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. 2008 Blood pmid:18349320
Cui L et al. Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development. 2008 Eukaryotic Cell pmid:18487348
Souto JA et al. Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities. 2008 ChemMedChem pmid:18537201
Lee JS et al. Inhibition of HIV-1 protease and RNase H of HIV-1 reverse transcriptase activities by long chain phenols from the sarcotestas of Ginkgo biloba. 2008 Planta Med. pmid:18543149
Chelikani R et al. Enzymatic polymerization of natural anacardic acid and antibiofouling effects of polyanacardic acid coatings. 2009 Appl. Biochem. Biotechnol. pmid:18592408
Schmeck B et al. Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression. 2008 J. Immunol. pmid:18606645
Philip JY et al. Isolation of anacardic acid from natural cashew nut shell liquid (CNSL) using supercritical carbon dioxide. 2008 J. Agric. Food Chem. pmid:18811166
De Lima SG et al. Effects of immature cashew nut-shell liquid (Anacardium occidentale) against oxidative damage in Saccharomyces cerevisiae and inhibition of acetylcholinesterase activity. 2008 Genet. Mol. Res. pmid:18949700
Kuo SC et al. 6-Pentadecylsalicylic acid: an antithrombin component isolated from the stem of Rhus semialata var. roxburghii. 1991 Planta Med. pmid:1896523
Wu J et al. Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. 2009 Bioorg. Med. Chem. pmid:19114310
Fukuda I et al. Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. 2009 Chem. Biol. pmid:19246003
Chandregowda V et al. Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity. 2009 Eur J Med Chem pmid:19246131
Wort SJ et al. Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites. 2009 J. Biol. Chem. pmid:19592490
Hung CH et al. Modulation of cytokine expression in human myeloid dendritic cells by environmental endocrine-disrupting chemicals involves epigenetic regulation. 2010 Environ. Health Perspect. pmid:20056579
Song C et al. Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration. 2010 Mol. Pharmacol. pmid:20097775
Awe S and Renkawitz-Pohl R Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster. 2010 Syst Biol Reprod Med pmid:20170286
Schultz DJ et al. Anacardic acid inhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell proliferation. 2010 Mol. Cancer Ther. pmid:20197399
Logrado LP et al. Synthesis and cytotoxicity screening of substituted isobenzofuranones designed from anacardic acids. 2010 Eur J Med Chem pmid:20537433
Tedong L et al. Hydro-ethanolic extract of cashew tree (Anacardium occidentale) nut and its principal compound, anacardic acid, stimulate glucose uptake in C2C12 muscle cells. 2010 Mol Nutr Food Res pmid:20603833
Ghizzoni M et al. Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. 2010 Bioorg. Med. Chem. pmid:20655754
Souto JA et al. New anacardic acid-inspired benzamides: histone lysine acetyltransferase activators. 2010 ChemMedChem pmid:20683922
Oliveira MS et al. Antioxidant, larvicidal and antiacetylcholinesterase activities of cashew nut shell liquid constituents. 2011 Acta Trop. pmid:20707981
Sukumari-Ramesh S et al. Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells. 2011 J. Neurosurg. pmid:21275565
Colussi C et al. Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21282606
Peña AN et al. MRG15 activates the cdc2 promoter via histone acetylation in human cells. 2011 Exp. Cell Res. pmid:21324423
Pandey D et al. SUMO1 negatively regulates reactive oxygen species production from NADPH oxidases. 2011 Arterioscler. Thromb. Vasc. Biol. pmid:21527745
Hsieh CC et al. Lunasin-aspirin combination against NIH/3T3 cells transformation induced by chemical carcinogens. 2011 Plant Foods Hum Nutr pmid:21562729
Song C et al. Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration. 2011 Neurotoxicology pmid:21777615
Wu Y et al. Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases signaling pathway. 2011 J. Pharmacol. Exp. Ther. pmid:21828260
Shimura M et al. Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation. 2011 J. Cell Biol. pmid:21875947
Hemshekhar M et al. Emerging roles of anacardic acid and its derivatives: a pharmacological overview. 2012 Basic Clin. Pharmacol. Toxicol. pmid:22103711
Rajendran P et al. Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. 2011 Clin Epigenetics pmid:22247744
Devipriya B and Kumaradhas P Probing the effect of intermolecular interaction and understanding the electrostatic moments of anacardic acid in the active site of p300 enzyme via DFT and charge density analysis. 2012 J. Mol. Graph. Model. pmid:22306413
Jain S et al. Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival. 2012 Breast Cancer Res. Treat. pmid:22562121
Omanakuttan A et al. Anacardic acid inhibits the catalytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9. 2012 Mol. Pharmacol. pmid:22745359
Wisastra R et al. Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases. 2012 Bioorg. Med. Chem. pmid:22789707
Park WJ and Ma E Inhibition of PCAF histone acetyltransferase and cytotoxic effect of N-acylanthranilic acids. 2012 Arch. Pharm. Res. pmid:22941480
Kusio-Kobialka M et al. Inhibition of PCAF by anacardic acid derivative leads to apoptosis and breaks resistance to DNA damage in BCR-ABL-expressing cells. 2013 Anticancer Agents Med Chem pmid:23157591
Kim MK et al. Topical application of anacardic acid (6-nonadecyl salicylic acid) reduces UV-induced histone modification, MMP-13, MMP-9, COX-2 and TNF-α expressions in hairless mice skin. 2013 J. Dermatol. Sci. pmid:23228850
Kuno A et al. Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein. 2013 J. Biol. Chem. pmid:23297412
Seong YA et al. Anacardic acid induces mitochondrial-mediated apoptosis in the A549 human lung adenocarcinoma cells. 2013 Int. J. Oncol. pmid:23314312
Mamidyala SK et al. Efficient synthesis of anacardic acid analogues and their antibacterial activities. 2013 Bioorg. Med. Chem. Lett. pmid:23416004
Sun Y et al. Epigenetic regulation of spinal CXCR2 signaling in incisional hypersensitivity in mice. 2013 Anesthesiology pmid:23756451
Azad MA et al. Electrolysed reduced water decreases reactive oxygen species-induced oxidative damage to skeletal muscle and improves performance in broiler chickens exposed to medium-term chronic heat stress. 2013 Br. Poult. Sci. pmid:23815735
Seong YA et al. Induction of the endoplasmic reticulum stress and autophagy in human lung carcinoma A549 cells by anacardic acid. 2014 Cell Biochem. Biophys. pmid:23955513
Hung CH et al. Environmental alkylphenols modulate cytokine expression in plasmacytoid dendritic cells. 2013 PLoS ONE pmid:24039973
Ravnskjaer K et al. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. 2013 J. Clin. Invest. pmid:24051374
Liu Z et al. Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene. 2013 Acta Biochim. Biophys. Sin. (Shanghai) pmid:24096006
Wisastra R et al. Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection. 2013 Bioorg. Med. Chem. pmid:24231650
Legut M et al. Anacardic acid enhances the anticancer activity of liposomal mitoxantrone towards melanoma cell lines - in vitro studies. 2014 Int J Nanomedicine pmid:24489469
Zhou Q et al. Small ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor α. 2014 FEBS J. pmid:24819975
Huang H et al. Anacardic acid induces cell apoptosis associated with induction of ATF4-dependent endoplasmic reticulum stress. 2014 Toxicol. Lett. pmid:24853302
Horibe T et al. Discovery of protein disulfide isomerase P5 inhibitors that reduce the secretion of MICA from cancer cells. 2014 Chembiochem pmid:24920482
Xiu YL et al. Anacardic acid enhances the proliferation of human ovarian cancer cells. 2014 PLoS ONE pmid:24921663
Silveira C et al. Anacardic acid from brazilian cashew nut trees reduces dentine erosion. 2014 Caries Res. pmid:24993776
Peng C et al. Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy. 2014 PLoS ONE pmid:25101666
Hoellein A et al. Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma. 2014 Blood pmid:25143484
Mariño G et al. Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers. 2014 Autophagy pmid:25484097
Hundt J et al. The inhibitory effects of anacardic acid on hepatitis C virus life cycle. 2015 PLoS ONE pmid:25658101
Shilpa P et al. Anti-metastatic action of anacardic acid targets VEGF-induced signalling pathways in epithelial to mesenchymal transition. 2015 Drug Discov Ther pmid:25788052
Peng C et al. Alcohol-induced histone H3K9 hyperacetylation and cardiac hypertrophy are reversed by a histone acetylases inhibitor anacardic acid in developing murine hearts. 2015 Biochimie pmid:25797917
Leite Ade S et al. Evaluation of toxic, cytotoxic, mutagenic, and antimutagenic activities of natural and technical cashew nut shell liquids using the Allium cepa and Artemia salina bioassays. 2015 Biomed Res Int pmid:25861638
Tsai YJ et al. Histone acetyltransferase p300 is induced by p38MAPK after photodynamic therapy: the therapeutic response is increased by the p300HAT inhibitor anacardic acid. 2015 Free Radic. Biol. Med. pmid:26001729
Tan CS et al. Epigenetic Regulation of Cytosolic Phospholipase A2 in SH-SY5Y Human Neuroblastoma Cells. 2016 Mol. Neurobiol. pmid:26162318
Meraviglia V et al. Acetylation mediates Cx43 reduction caused by electrical stimulation. 2015 J. Mol. Cell. Cardiol. pmid:26264759
Gnanaprakasam JNR et al. The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-κB. 2015 Int. Immunopharmacol. pmid:26371858
Muzaffar S et al. Anacardic acid induces apoptosis-like cell death in the rice blast fungus Magnaporthe oryzae. 2016 Appl. Microbiol. Biotechnol. pmid:26381667
Wapenaar H et al. Enzyme kinetics and inhibition of histone acetyltransferase KAT8. 2015 Eur J Med Chem pmid:26505788
Re A et al. Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways. 2016 Endocrine pmid:26547215
Wu TC et al. The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase. 2016 Toxicol. Appl. Pharmacol. pmid:26768552
Yao K et al. Anacardic acid sensitizes prostate cancer cells to radiation therapy by regulating H2AX expression. 2015 Int J Clin Exp Pathol pmid:26884865
Al-Bataineh MM et al. Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells. 2016 Am. J. Physiol. Renal Physiol. pmid:26911844
Harsha Raj M et al. Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer cells by the regulation of p53, MAPK and NFκβ pathways. 2016 Apoptosis pmid:26921178

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