Gamma-butyrolactone is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Gamma-butyrolactone
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pseudomonas Infections | D011552 | 25 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chikara S et al. | Enterolactone Induces G1-phase Cell Cycle Arrest in Nonsmall Cell Lung Cancer Cells by Downregulating Cyclins and Cyclin-dependent Kinases. | 2017 May-Jun | Nutr Cancer | pmid:28323486 |
| Lai BM et al. | Control of the pollution of antibiotic resistance genes in soils by quorum sensing inhibition. | 2017 | Environ Sci Pollut Res Int | pmid:28004368 |
| Chou KC et al. | Biosynthesis of Antroquinonol and 4-Acetylantroquinonol B via a Polyketide Pathway Using Orsellinic Acid as a Ring Precursor in Antrodia cinnamomea. | 2017 | J. Agric. Food Chem. | pmid:28001060 |
| Aquea F et al. | Chemical inhibition of the histone acetyltransferase activity in Arabidopsis thaliana. | 2017 | Biochem. Biophys. Res. Commun. | pmid:27993678 |
| Mattioli S et al. | Performance and egg quality of laying hens fed flaxseed: highlights on n-3 fatty acids, cholesterol, lignans and isoflavones. | 2017 | Animal | pmid:27819218 |
| Verbeurgt C et al. | The human bitter taste receptor T2R38 is broadly tuned for bacterial compounds. | 2017 | PLoS ONE | pmid:28902853 |
| Balhouse BN et al. | N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro. | 2017 | PLoS ONE | pmid:28692660 |
| Mao B et al. | Catalytic Asymmetric Synthesis of Butenolides and Butyrolactones. | 2017 | Chem. Rev. | pmid:28640622 |
| Tanui CK et al. | Influence of the ferric uptake regulator (Fur) protein on pathogenicity in Pectobacterium carotovorum subsp. brasiliense. | 2017 | PLoS ONE | pmid:28545065 |
| Tsujino Y | A New Agonist for Peroxisome Proliferation-activated Receptor γ (PPARγ), Fraglide-1 from Zhenjiang Fragrant Vinegar: Screening and Characterization Based on Cell Culture Experiments. | 2017 | J Oleo Sci | pmid:28515383 |
| Ziegler A et al. | Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses. | 2017 | J. Am. Vet. Med. Assoc. | pmid:28509650 |
| López M et al. | Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme. | 2017 | PLoS ONE | pmid:28328989 |
| Saurav K et al. | Quorum Sensing Inhibitors from the Sea Discovered Using Bacterial N-acyl-homoserine Lactone-Based Biosensors. | 2017 | Mar Drugs | pmid:28241461 |
| Zhu Y et al. | Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors. | 2017 | PLoS ONE | pmid:28152041 |
| Lima DF et al. | Seasonal change in main alkaloids of jaborandi (Pilocarpus microphyllus Stapf ex Wardleworth), an economically important species from the Brazilian flora. | 2017 | PLoS ONE | pmid:28151972 |
| Chikara S et al. | Enterolactone alters FAK-Src signaling and suppresses migration and invasion of lung cancer cell lines. | 2017 | BMC Complement Altern Med | pmid:28068967 |
| Sokolova OS et al. | Structural Basis of Arp2/3 Complex Inhibition by GMF, Coronin, and Arpin. | 2017 | J. Mol. Biol. | pmid:27939292 |
| Lima TC et al. | In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (-)-cubebin derivatives (-)-hinokinin and (-)-O-benzylcubebin. | 2017 | Bioorg. Med. Chem. Lett. | pmid:27955811 |
| Yatmaz AH et al. | Quantification of Fraglide-1, a New Functional Ingredient, in Vinegars. | 2017 | J Oleo Sci | pmid:29129902 |
| Sultan SP et al. | Characterization of AvaR1, a butenolide-autoregulator receptor for biosynthesis of a Streptomyces hormone in Streptomyces avermitilis. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27541747 |
| Liu X et al. | Screening of Bioactive Ingredients in Ligusticum Chuanxiong Hort for Protection against Myocardial Ischemia. | 2016 | Cell. Physiol. Biochem. | pmid:27915331 |
| Turrini NG et al. | Sequential Enzymatic Conversion of α-Angelica Lactone to γ-Valerolactone through Hydride-Independent C=C Bond Isomerization. | 2016 | ChemSusChem | pmid:27885835 |
| Patterson AG et al. | Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems. | 2016 | Mol. Cell | pmid:27867010 |
| Zhu J et al. | AvaR2, a pseudo γ-butyrolactone receptor homologue from Streptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth. | 2016 | Mol. Microbiol. | pmid:27502190 |
| Bauer JS et al. | The Systematic Investigation of the Quorum Sensing System of the Biocontrol Strain Pseudomonas chlororaphis subsp. aurantiaca PB-St2 Unveils aurI to Be a Biosynthetic Origin for 3-Oxo-Homoserine Lactones. | 2016 | PLoS ONE | pmid:27861617 |
| Chen CY et al. | Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage. | 2016 | Toxins (Basel) | pmid:27827950 |
| An X et al. | Three New Butenolides from the Fungus Aspergillus sp. CBS-P-2. | 2016 | Molecules | pmid:27754391 |
| Schröder L et al. | Effects of Phytoestrogen Extracts Isolated from Elder Flower on Hormone Production and Receptor Expression of Trophoblast Tumor Cells JEG-3 and BeWo, as well as MCF7 Breast Cancer Cells. | 2016 | Nutrients | pmid:27740591 |
| Tashiro Y et al. | Directed evolution of the autoinducer selectivity of Vibrio fischeri LuxR. | 2016 | J. Gen. Appl. Microbiol. | pmid:27725402 |
| Zhao LX et al. | Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages. | 2016 | PLoS ONE | pmid:27716839 |
| Liu DM et al. | Cytoproliferative and Cytoprotective Effects of Striatisporolide A Isolated from Rhizomes of Athyrium multidentatum (Doell.) Ching on Human Umbilical Vein Endothelial Cells. | 2016 | Molecules | pmid:27669209 |
| Priya R et al. | Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. | 2016 | Cell Cycle | pmid:27650961 |
| Brisdelli F et al. | Protolichesterinic acid enhances doxorubicin-induced apoptosis in HeLa cells in vitro. | 2016 | Life Sci. | pmid:27363900 |
| Guo Q et al. | Potential Use of Dimethyl Sulfoxide in Treatment of Infections Caused by Pseudomonas aeruginosa. | 2016 | Antimicrob. Agents Chemother. | pmid:27645245 |
| Han Q et al. | Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells. | 2016 | Cell Death Dis | pmid:27584788 |
| Rochford K et al. | Volatile Organic Compound Gamma-Butyrolactone Released upon Herpes Simplex Virus Type -1 Acute Infection Modulated Membrane Potential and Repressed Viral Infection in Human Neuron-Like Cells. | 2016 | PLoS ONE | pmid:27537375 |
| de Saint Germain A et al. | An histidine covalent receptor and butenolide complex mediates strigolactone perception. | 2016 | Nat. Chem. Biol. | pmid:27479744 |
| Rehman SU et al. | In Vitro Assessment of CYP-Mediated Drug Interactions for Kinsenoside, an Antihyperlipidemic Candidate. | 2016 | Molecules | pmid:27322236 |
| Valera MJ et al. | GqqA, a novel protein in Komagataeibacter europaeus involved in bacterial quorum quenching and cellulose formation. | 2016 | Microb. Cell Fact. | pmid:27221658 |
| Last D et al. | Fast, Continuous, and High-Throughput (Bio)Chemical Activity Assay for N-Acyl-l-Homoserine Lactone Quorum-Quenching Enzymes. | 2016 | Appl. Environ. Microbiol. | pmid:27208131 |
| Behrens J et al. | Coronin 1C-free primary mouse fibroblasts exhibit robust rearrangements in the orientation of actin filaments, microtubules and intermediate filaments. | 2016 | Eur. J. Cell Biol. | pmid:27178841 |
| Zhang C et al. | Characterization of N-acyl homoserine lactones (AHLs) producing bacteria isolated from vacuum-packaged refrigerated turbot (Scophthalmus maximus) and possible influence of exogenous AHLs on bacterial phenotype. | 2016 | J. Gen. Appl. Microbiol. | pmid:27118073 |
| Zeng J et al. | Mechanism of azithromycin inhibition of HSL synthesis in Pseudomonas aeruginosa. | 2016 | Sci Rep | pmid:27075730 |
| Cheema AK et al. | Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis. | 2016 | PLoS ONE | pmid:27073845 |
| Cunha NL et al. | (-)-Hinokinin Induces G2/M Arrest and Contributes to the Antiproliferative Effects of Doxorubicin in Breast Cancer Cells. | 2016 | Planta Med. | pmid:27002393 |
| Singh N et al. | Inhibition of fatty acid synthase is protective in pulmonary hypertension. | 2016 | Br. J. Pharmacol. | pmid:27061087 |
| Holm A et al. | Pseudomonas aeruginosa N-3-oxo-dodecanoyl-homoserine Lactone Elicits Changes in Cell Volume, Morphology, and AQP9 Characteristics in Macrophages. | 2016 | Front Cell Infect Microbiol | pmid:27047801 |
| Slebe F et al. | FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth. | 2016 | Nat Commun | pmid:27045898 |
| Hu PY et al. | Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood-Brain Barrier in Vitro Model. | 2016 | Molecules | pmid:26950101 |
| Hsiao HB et al. | Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses. | 2016 | BMC Complement Altern Med | pmid:26916550 |
| Johnson WM et al. | Evidence for quorum sensing and differential metabolite production by a marine bacterium in response to DMSP. | 2016 | ISME J | pmid:26882264 |
| Goh SY et al. | Quorum sensing activity of Citrobacter amalonaticus L8A, a bacterium isolated from dental plaque. | 2016 | Sci Rep | pmid:26860259 |
| Talactac MR et al. | Virucidal activity of Haemaphysalis longicornis longicin P4 peptide against tick-borne encephalitis virus surrogate Langat virus. | 2016 | Parasit Vectors | pmid:26830840 |
| Grant PK et al. | Orthogonal intercellular signaling for programmed spatial behavior. | 2016 | Mol. Syst. Biol. | pmid:26814193 |
| Wu Y et al. | New α-Methylene-γ-Butyrolactone Derivatives as Potential Fungicidal Agents: Design, Synthesis and Antifungal Activities. | 2016 | Molecules | pmid:26805804 |
| Lin L et al. | DqsIR quorum sensing-mediated gene regulation of the extremophilic bacterium Deinococcus radiodurans in response to oxidative stress. | 2016 | Mol. Microbiol. | pmid:26789904 |
| Gaida MM et al. | Sensing developing biofilms: the bitter receptor T2R38 on myeloid cells. | 2016 | Pathog Dis | pmid:26782143 |
| Arcaro J et al. | The hippocampus participates in a pharmacological rat model of absence seizures. | 2016 | Epilepsy Res. | pmid:26773250 |
| Zhao G et al. | N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins. | 2016 | Oncotarget | pmid:26758417 |
| Soper C et al. | Optogenetic activation of superior colliculus neurons suppresses seizures originating in diverse brain networks. | 2016 | Neurobiol. Dis. | pmid:26721319 |
| Boruta T and Bizukojc M | Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26603760 |
| Kuncewitch M et al. | Inhibition of fatty acid synthase with C75 decreases organ injury after hemorrhagic shock. | 2016 | Surgery | pmid:26372196 |
| Idrovo JP et al. | Inhibition of lipogenesis reduces inflammation and organ injury in sepsis. | 2016 | J. Surg. Res. | pmid:26216747 |
| Tamura M et al. | Effects of an equol-producing bacterium isolated from human faeces on isoflavone and lignan metabolism in mice. | 2016 | J. Sci. Food Agric. | pmid:26455424 |
| Rau MH et al. | Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals. | 2016 | Microb. Cell Fact. | pmid:27737709 |
| Reger MK et al. | Urinary phytoestrogens and cancer, cardiovascular, and all-cause mortality in the continuous National Health and Nutrition Examination Survey. | 2016 | Eur J Nutr | pmid:25943648 |
| Barton MH et al. | Effect of firocoxib on cyclooxygenase 2, microsomal prostaglandin E2 synthase 1, and cytosolic phospholipase A2 gene expression in equine mononuclear cells. | 2015 | Am. J. Vet. Res. | pmid:26618729 |
| Xiao W et al. | Ligustilide treatment promotes functional recovery in a rat model of spinal cord injury via preventing ROS production. | 2015 | Int J Clin Exp Pathol | pmid:26722386 |
| Bucio-Cano A et al. | Targeting quorum sensing by designing azoline derivatives to inhibit the N-hexanoyl homoserine lactone-receptor CviR: Synthesis as well as biological and theoretical evaluations. | 2015 | Bioorg. Med. Chem. | pmid:26654469 |
| Simon S et al. | Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway. | 2015 | PLoS Pathog. | pmid:26633832 |
| Truong TT et al. | A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone. | 2015 | J. Bacteriol. | pmid:26283771 |
| Shin HS et al. | Enhancing Effect of Trachelogenin from Trachelospermi caulis Extract on Intestinal Barrier Function. | 2015 | Biol. Pharm. Bull. | pmid:26268064 |
| Li C et al. | Diastereodivergent and Enantioselective [4+2] Annulations of γ-Butenolides with Cyclic 1-Azadienes. | 2015 | Molecules | pmid:26225947 |
| Reddyjarugu B et al. | Analgesic Efficacy of Firocoxib, a Selective Inhibitor of Cyclooxygenase 2, in a Mouse Model of Incisional Pain. | 2015 | J. Am. Assoc. Lab. Anim. Sci. | pmid:26224441 |
| Yu J et al. | Protective HSP70 Induction by Z-Ligustilide against Oxygen-Glucose Deprivation Injury via Activation of the MAPK Pathway but Not of HSF1. | 2015 | Biol. Pharm. Bull. | pmid:26212861 |
| Wang T and Hoye TR | Diels-Alderase-free, bis-pericyclic, [4+2] dimerization in the biosynthesis of (±)-paracaseolide A. | 2015 | Nat Chem | pmid:26201740 |
| Bortolotti D et al. | Pseudomonas aeruginosa Quorum Sensing Molecule N-(3-Oxododecanoyl)-L-Homoserine-Lactone Induces HLA-G Expression in Human Immune Cells. | 2015 | Infect. Immun. | pmid:26195547 |
| Biarnes-Carrera M et al. | Butyrolactone signalling circuits for synthetic biology. | 2015 | Curr Opin Chem Biol | pmid:26164547 |
| Patel AV et al. | Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors. | 2015 | Neuro-oncology | pmid:26116612 |
| Adgent MA and Rogan WJ | Triclosan and prescription antibiotic exposures and enterolactone production in adults. | 2015 | Environ. Res. | pmid:26114916 |
| Mellbye BL et al. | Nitrite-Oxidizing Bacterium Nitrobacter winogradskyi Produces N-Acyl-Homoserine Lactone Autoinducers. | 2015 | Appl. Environ. Microbiol. | pmid:26092466 |
| Liu Y et al. | Antiproliferative Compounds from Cleistanthus boivinianus from the Madagascar Dry Forest. | 2015 | J. Nat. Prod. | pmid:26091020 |
| Certner RH and Vollmer SV | Evidence for Autoinduction and Quorum Sensing in White Band Disease-Causing Microbes on Acropora cervicornis. | 2015 | Sci Rep | pmid:26047488 |
| Golpasha ID et al. | Immunization with 3-oxododecanoyl-L-homoserine lactone-r-PcrV conjugate enhances survival of mice against lethal burn infections caused by Pseudomonas aeruginosa. | 2015 | Bosn J Basic Med Sci | pmid:26042508 |
| DiGruccio MR et al. | Hyperexcitability of rat thalamocortical networks after exposure to general anesthesia during brain development. | 2015 | J. Neurosci. | pmid:25632125 |
| Schwarzer C et al. | Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone. | 2015 | J. Biol. Chem. | pmid:25627690 |
| Modarresi F et al. | Iron limitation enhances acyl homoserine lactone (AHL) production and biofilm formation in clinical isolates of Acinetobacter baumannii. | 2015 | Virulence | pmid:25622119 |
| Kowalewski MP et al. | Formation of the early canine CL and the role of prostaglandin E2 (PGE2) in regulation of its function: an in vivo approach. | 2015 | Theriogenology | pmid:25595355 |
| Kem MP et al. | Fatty acid hydrolysis of acyl marinobactin siderophores by Marinobacter acylases. | 2015 | Biochemistry | pmid:25588131 |
| Seviour T et al. | Functional amyloids keep quorum-sensing molecules in check. | 2015 | J. Biol. Chem. | pmid:25586180 |
| Hullar MA et al. | Enterolignan-producing phenotypes are associated with increased gut microbial diversity and altered composition in premenopausal women in the United States. | 2015 | Cancer Epidemiol. Biomarkers Prev. | pmid:25542830 |
| Goodman CG et al. | Enantioconvergent synthesis of functionalized γ-butyrolactones via (3 + 2)-annulation. | 2015 | J. Am. Chem. Soc. | pmid:25533016 |
| Weiland-Bräuer N et al. | Novel reporter for identification of interference with acyl homoserine lactone and autoinducer-2 quorum sensing. | 2015 | Appl. Environ. Microbiol. | pmid:25527543 |
| Cude WN et al. | Phaeobacter sp. strain Y4I utilizes two separate cell-to-cell communication systems to regulate production of the antimicrobial indigoidine. | 2015 | Appl. Environ. Microbiol. | pmid:25527537 |
| Vo TN et al. | In vitro and in vivo evaluation of self-mineralization and biocompatibility of injectable, dual-gelling hydrogels for bone tissue engineering. | 2015 | J Control Release | pmid:25483428 |
| Gerdt JP et al. | Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR. | 2015 | Org. Biomol. Chem. | pmid:25474181 |
| Lu W et al. | A 3'UTR-associated RNA, FLJ11812 maintains stemness of human embryonic stem cells by targeting miR-4459. | 2015 | Stem Cells Dev. | pmid:25437332 |
| Su S et al. | Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells. | 2015 | Phytomedicine | pmid:25765837 |
| Hallé C et al. | Effects of different n-6:n-3 fatty acid ratios and of enterolactone on gene expression and PG secretion in bovine endometrial cells. | 2015 | Br. J. Nutr. | pmid:25366386 |
| Castillo S et al. | 2(5H)-Furanone, epigallocatechin gallate, and a citric-based disinfectant disturb quorum-sensing activity and reduce motility and biofilm formation of Campylobacter jejuni. | 2015 | Folia Microbiol. (Praha) | pmid:25231135 |