Gamma-butyrolactone

Gamma-butyrolactone is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 14993 references associated with Gamma-butyrolactone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Gamma-butyrolactone

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Gamma-butyrolactone

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Ataxia D001259 20 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Weight Loss D015431 56 associated lipids
Total 9

PubChem Biomolecular Interactions and Pathways

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All references with Gamma-butyrolactone

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Authors Title Published Journal PubMed Link
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Onaka H et al. Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis. 1998 Mol. Microbiol. pmid:9643542
Harris SJ et al. The hexA gene of Erwinia carotovora encodes a LysR homologue and regulates motility and the expression of multiple virulence determinants. 1998 Mol. Microbiol. pmid:9643539
Nakano H et al. Gene replacement analysis of the Streptomyces virginiae barA gene encoding the butyrolactone autoregulator receptor reveals that BarA acts as a repressor in virginiamycin biosynthesis. 1998 J. Bacteriol. pmid:9642182
von Bodman SB et al. A negative regulator mediates quorum-sensing control of exopolysaccharide production in Pantoea stewartii subsp. stewartii. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9636211
Sawa T et al. In vitro cellular toxicity predicts Pseudomonas aeruginosa virulence in lung infections. 1998 Infect. Immun. pmid:9632591
Flavier AB et al. An RpoS (sigmaS) homologue regulates acylhomoserine lactone-dependent autoinduction in Ralstonia solanacearum. 1998 Mol. Microbiol. pmid:9632252
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Jiang Y et al. In vitro biosynthesis of the Pseudomonas aeruginosa quorum-sensing signal molecule N-butanoyl-L-homoserine lactone. 1998 Mol. Microbiol. pmid:9593307
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Kolter R and Losick R One for all and all for one. 1998 Science pmid:9565532
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Davies DG et al. The involvement of cell-to-cell signals in the development of a bacterial biofilm. 1998 Science pmid:9535661
Harris BZ et al. The guanosine nucleotide (p)ppGpp initiates development and A-factor production in myxococcus xanthus. 1998 Genes Dev. pmid:9531539
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Kaji H et al. The endogenous feeding suppressant, 2-buten-4-olide, impairs the pulsatile secretion of luteinizing hormone through endogenous opioid peptides. 1998 Eur. J. Endocrinol. pmid:9506867
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Lu Y et al. Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells. 1998 Oncogene pmid:9488034
Liao CH et al. Bakkenolide G, a natural PAF-receptor antagonist. 1997 J. Pharm. Pharmacol. pmid:9466352
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Kanemitsu MY et al. Cdc2-mediated phosphorylation of the gap junction protein, connexin43, during mitosis. 1998 Cell Growth Differ. pmid:9438384
Telford G et al. The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. 1998 Infect. Immun. pmid:9423836
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Ando N et al. Involvement of afsA in A-factor biosynthesis as a key enzyme. 1997 J. Antibiot. pmid:9402990
Wood DW et al. N-acyl-homoserine lactone-mediated regulation of phenazine gene expression by Pseudomonas aureofaciens 30-84 in the wheat rhizosphere. 1997 J. Bacteriol. pmid:9401023
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Puskas A et al. A quorum-sensing system in the free-living photosynthetic bacterium Rhodobacter sphaeroides. 1997 J. Bacteriol. pmid:9393720
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Flavier AB et al. Hierarchical autoinduction in Ralstonia solanacearum: control of acyl-homoserine lactone production by a novel autoregulatory system responsive to 3-hydroxypalmitic acid methyl ester. 1997 J. Bacteriol. pmid:9371457
Kinoshita H et al. Butyrolactone autoregulator receptor protein (BarA) as a transcriptional regulator in Streptomyces virginiae. 1997 J. Bacteriol. pmid:9371444
Gamard P et al. Novel butyrolactones with antifungal activity produced by Pseudomonas aureofaciens strain 63-28. 1997 J. Antibiot. pmid:9360619
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Ingram D et al. Case-control study of phyto-oestrogens and breast cancer. 1997 Lancet pmid:9329514
McLean RJ et al. Evidence of autoinducer activity in naturally occurring biofilms. 1997 FEMS Microbiol. Lett. pmid:9311122
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Swift S et al. Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules. 1997 J. Bacteriol. pmid:9286976
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Hein S et al. Biosynthesis of poly(4-hydroxybutyric acid) by recombinant strains of Escherichia coli. 1997 FEMS Microbiol. Lett. pmid:9271870
Waki M et al. Cloning and characterization of the gene (farA) encoding the receptor for an extracellular regulatory factor (IM-2) from Streptomyces sp. strain FRI-5. 1997 J. Bacteriol. pmid:9260956
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Williams KL et al. Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site. 1997 Mol. Pharmacol. pmid:9224820
Morton MS et al. Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom. 1997 Prostate pmid:9215400
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Rodríguez AM et al. Structure-cytoprotective activity relationship of simple molecules containing an alpha,beta-unsaturated carbonyl system. 1997 J. Med. Chem. pmid:9191959
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Shaw PD et al. Detecting and characterizing N-acyl-homoserine lactone signal molecules by thin-layer chromatography. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9177164
Badawey el-S T and Kappe Synthesis and in vitro anti-HIV activity of certain 2-(1H-benzimidazol-2-ylamino)pyrimidin-4(3H)-ones and related derivatives. 1997 Arch. Pharm. (Weinheim) pmid:9167448
Reimmann C et al. The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase. 1997 Mol. Microbiol. pmid:9159518
Mukherjee A et al. Molecular characterization and expression of the Erwinia carotovora hrpNEcc gene, which encodes an elicitor of the hypersensitive reaction. 1997 Mol. Plant Microbe Interact. pmid:9150595
Pesci EC et al. Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. 1997 J. Bacteriol. pmid:9150205
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Onaka H et al. A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability. 1997 J. Bacteriol. pmid:9098075
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Totsukawa G et al. Mitosis-specific phosphorylation of smooth muscle regulatory light chain of myosin II at Ser-1 and/or -2 and Thr-9 in sea urchin egg extract. 1996 Cell Struct. Funct. pmid:9078405
Gross RA et al. Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones. 1997 J. Pharmacol. Exp. Ther. pmid:9023280