Gamma-butyrolactone

Gamma-butyrolactone is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 14993 references associated with Gamma-butyrolactone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Gamma-butyrolactone

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Gamma-butyrolactone

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Ataxia D001259 20 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Weight Loss D015431 56 associated lipids
Total 9

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Gamma-butyrolactone

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Authors Title Published Journal PubMed Link
Salehi-Najafabadi Z et al. The gamma-butyrolactone receptors BulR1 and BulR2 of Streptomyces tsukubaensis: tacrolimus (FK506) and butyrolactone synthetases production control. 2014 Appl. Microbiol. Biotechnol. pmid:24562179
Kolomytseva M et al. Structural basis for the substrate specificity and the absence of dehalogenation activity in 2-chloromuconate cycloisomerase from Rhodococcus opacus 1CP. 2014 Biochim. Biophys. Acta pmid:24768773
Taguchi R et al. Mucin 3 is involved in intestinal epithelial cell apoptosis via N-(3-oxododecanoyl)-L-homoserine lactone-induced suppression of Akt phosphorylation. 2014 Am. J. Physiol., Cell Physiol. pmid:24848113
Chen L et al. Comparative safety of the antifouling compound butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) to the marine medaka (Oryzias melastigma). 2014 Aquat. Toxicol. pmid:24583292
Holban AM et al. Role of Pseudomonas aeruginosa quorum sensing (QS) molecules on the viability and cytokine profile of human mesenchymal stem cells. 2014 Virulence pmid:24398422
Volova T et al. A glucose-utilizing strain, Cupriavidus euthrophus B-10646: growth kinetics, characterization and synthesis of multicomponent PHAs. 2014 PLoS ONE pmid:24586280
Chen C et al. 4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial function. 2014 J. Biol. Chem. pmid:24784139
Mascal M et al. Hydrodeoxygenation of the angelica lactone dimer, a cellulose-based feedstock: simple, high-yield synthesis of branched C7 -C10 gasoline-like hydrocarbons. 2014 Angew. Chem. Int. Ed. Engl. pmid:24474249
McFadden JW et al. Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation. 2014 PLoS ONE pmid:25541737
Chang CY et al. Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target. 2014 Sci Rep pmid:25430794
Carbonell-Ballestero M et al. A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology. 2014 Nucleic Acids Res. pmid:25404136
McCann MJ et al. The anti-proliferative effects of enterolactone in prostate cancer cells: evidence for the role of DNA licencing genes, mi-R106b cluster expression, and PTEN dosage. 2014 Nutrients pmid:25372501
Yang B et al. Sinulolides A-H, new cyclopentenone and butenolide derivatives from soft coral Sinularia sp. 2014 Mar Drugs pmid:25342460
Zhang Y et al. Efficient synthesis of kinsenoside and goodyeroside a by a chemo-enzymatic approach. 2014 Molecules pmid:25340300
Sadowski MC et al. The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer. 2014 Oncotarget pmid:25313139
Marcotullio MC et al. Hinokinin, an emerging bioactive lignan. 2014 Molecules pmid:25232707
Nodwell JR Are you talking to me? A possible role for γ-butyrolactones in interspecies signalling. 2014 Mol. Microbiol. pmid:25200025
Tan WS et al. Pantoea sp. isolated from tropical fresh water exhibiting N-acyl homoserine lactone production. 2014 ScientificWorldJournal pmid:25197715
Zeller MA et al. Butyrolactone synthesis via polar radical crossover cycloaddition reactions: diastereoselective syntheses of methylenolactocin and protolichesterinic acid. 2014 Org. Lett. pmid:25190259
Kumar AS et al. Bacterial quorum sensing molecule N-3-oxo-dodecanoyl-L-homoserine lactone causes direct cytotoxicity and reduced cell motility in human pancreatic carcinoma cells. 2014 PLoS ONE pmid:25188245
Bazire A and Dufour A The Pseudomonas aeruginosa rhlG and rhlAB genes are inversely regulated and RhlG is not required for rhamnolipid synthesis. 2014 BMC Microbiol. pmid:24943492
O'Sullivan D et al. Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development. 2014 Immunity pmid:25001241
Grabiner MA et al. Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2α. 2014 J. Immunol. pmid:24990083
Peng N et al. An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E⁻/⁻ mice. 2014 Sci Rep pmid:24980430
Frankenfeld CL Cardiometabolic risk factors are associated with high urinary enterolactone concentration, independent of urinary enterodiol concentration and dietary fiber intake in adults. 2014 J. Nutr. pmid:24966407
Chu W et al. Quorum quenching bacteria Bacillus sp. QSI-1 protect zebrafish (Danio rerio) from Aeromonas hydrophila infection. 2014 Sci Rep pmid:24962441
Sun Y et al. Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2. 2014 Cancer Biol. Ther. pmid:24918434
Ge D et al. Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells. 2014 Autophagy pmid:24879147
Yunos NY et al. Discovery of Pantoea rodasii strain ND03 that produces N-(3-Oxo-hexanoyl)-L-homoserine lactone. 2014 Sensors (Basel) pmid:24859023
Gardères J et al. Cellular effects of bacterial N-3-Oxo-dodecanoyl-L-Homoserine lactone on the sponge Suberites domuncula (Olivi, 1792): insights into an intimate inter-kingdom dialogue. 2014 PLoS ONE pmid:24858701
Goh SY et al. Unusual multiple production of N-acylhomoserine lactones a by Burkholderia sp. strain C10B isolated from dentine caries. 2014 Sensors (Basel) pmid:24854358
Elkhateeb A et al. New terpenes from the Egyptian soft coral Sarcophyton ehrenbergi. 2014 Mar Drugs pmid:24699113
Jayachandran R et al. Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling. 2014 PLoS Biol. pmid:24667537
Schwarzer C et al. Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia. 2014 Am. J. Physiol., Cell Physiol. pmid:24598360
De S et al. Phosphorylation of α-tubulin by protein kinase C stimulates microtubule dynamics in human breast cells. 2014 Cytoskeleton (Hoboken) pmid:24574051
Miguel V et al. Role of ABCG2 in transport of the mammalian lignan enterolactone and its secretion into milk in Abcg2 knockout mice. 2014 Drug Metab. Dispos. pmid:24568887
Sun Q et al. Gut microbiota metabolites of dietary lignans and risk of type 2 diabetes: a prospective investigation in two cohorts of U.S. women. 2014 Diabetes Care pmid:24550220
Mumford SL et al. Higher urinary lignan concentrations in women but not men are positively associated with shorter time to pregnancy. 2014 J. Nutr. pmid:24401816
Swaminathan K et al. A Cdc42- and Rac-interactive binding (CRIB) domain mediates functions of coronin. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:24347642
Matsuo S et al. Fatty acid synthase inhibitor C75 ameliorates experimental colitis. 2014 Mol. Med. pmid:24306512
McInnis CE and Blackwell HE Non-native N-aroyl L-homoserine lactones are potent modulators of the quorum sensing receptor RpaR in Rhodopseudomonas palustris. 2014 Chembiochem pmid:24281952
Sun Q et al. Lappaol F, a novel anticancer agent isolated from plant arctium Lappa L. 2014 Mol. Cancer Ther. pmid:24222662
Studer SV et al. Non-native acylated homoserine lactones reveal that LuxIR quorum sensing promotes symbiont stability. 2014 Environ. Microbiol. pmid:24191970
Palliyil S et al. High-sensitivity monoclonal antibodies specific for homoserine lactones protect mice from lethal Pseudomonas aeruginosa infections. 2014 Appl. Environ. Microbiol. pmid:24185854
Vestby LK et al. Synthetic brominated furanone F202 prevents biofilm formation by potentially human pathogenic Escherichia coli O103:H2 and Salmonella ser. Agona on abiotic surfaces. 2014 J. Appl. Microbiol. pmid:24118802
Chandler KJ and Sutton DG The dilemmas of medicine selection for equine veterinarians. 2014 Equine Vet. J. pmid:24329584
Jongthawin J et al. PGE2 signaling and its biosynthesis-related enzymes in cholangiocarcinoma progression. 2014 Tumour Biol. pmid:24839005
Tsui HW et al. Effect of alcohol aggregation on the retention factors of chiral solutes with an amylose-based sorbent: modeling and implications for the adsorption mechanism. 2014 J Chromatogr A pmid:24444802
Tsuji W et al. Orally administered S-1 suppresses circulating endothelial cell counts in metastatic breast cancer patients. 2014 Int. J. Clin. Oncol. pmid:23739924
Barton MH et al. Efficacy of cyclo-oxygenase inhibition by two commercially available firocoxib products in horses. 2014 Equine Vet. J. pmid:23662599