Arachidonic acid

Arachidonic acid is a lipid of Fatty Acyls (FA) class. Arachidonic acid is associated with abnormalities such as Atherosclerosis, Ischemia, Hypertensive disease, Hypertension induced by pregnancy and Vascular ring of aorta. The involved functions are known as Platelet aggregation, Anabolism, Ion Transport, Signal Transduction Pathways and Signal. Arachidonic acid often locates in Extracellular, Body tissue, Protoplasm, Tissue membrane and soluble. The associated genes with Arachidonic acid are CYP2J2 gene, CYP2E1 gene, Recombinant Proteins, POR gene and P4HTM gene. The related lipids are Fatty Acids, Glycerophospholipids, Steroids, octadecadienoic acid and 9-hydroxy-10,12-octadecadienoic acid. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of Arachidonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Arachidonic acid?

Arachidonic acid is suspected in Ischemia, Hypertensive disease, Atherosclerosis, Hypertension induced by pregnancy, Vascular ring of aorta, Idiopathic pulmonary hypertension and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Arachidonic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Per page 10 20 50 100 | Total 411

PubChem Associated disorders and diseases

What pathways are associated with Arachidonic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Arachidonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Arachidonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Arachidonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Arachidonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Arachidonic acid?

Mouse Model

Mouse Model are used in the study 'Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein.' (Sun D and Funk CD, 1996).

Knock-out

Knock-out are used in the study 'Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia.' (Ho YS et al., 1997).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Arachidonic acid

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Per page 10 20 50 100 | Total 17105
Authors Title Published Journal PubMed Link
Fourie R et al. Pseudomonas aeruginosa produces aspirin insensitive eicosanoids and contributes to the eicosanoid profile of polymicrobial biofilms with Candida albicans. 2017 Prostaglandins Leukot. Essent. Fatty Acids pmid:28237086
Neuman JC et al. Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-Cell Function. 2017 Diabetes pmid:28193789
Lee Y et al. Analysis of endogenous lipids during intestinal wound healing. 2017 PLoS ONE pmid:28800645
Nakamura K et al. Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice. 2017 PLoS ONE pmid:28771600
Moschos MM et al. Anti-platelet effects of anti-glaucomatous eye drops: an in vitro study on human platelets. 2017 Drug Des Devel Ther pmid:28458520
Ruhanen H et al. Depletion of TM6SF2 disturbs membrane lipid composition and dynamics in HuH7 hepatoma cells. 2017 Biochim. Biophys. Acta pmid:28434889
Krzeszinski JY et al. Lipid Osteoclastokines Regulate Breast Cancer Bone Metastasis. 2017 Endocrinology pmid:27967239
Liao YR et al. Bioactive chemical constituents from the root bark of Morus australis. 2017 Bioorg. Med. Chem. Lett. pmid:27908762
Leroy C et al. Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. 2017 Prostaglandins Leukot. Essent. Fatty Acids pmid:28515017
Bijak M and Saluk-Bijak J Flavonolignans inhibit the arachidonic acid pathway in blood platelets. 2017 BMC Complement Altern Med pmid:28797264