Lmfa07050031

Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.

Cross Reference

Introduction

To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lmfa07050031

MeSH term MeSH ID Detail
Mercury Poisoning D008630 4 associated lipids
Placental Insufficiency D010927 6 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Cleft Lip D002971 8 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Hypoglycemia D007003 13 associated lipids
Ketosis D007662 13 associated lipids
Cachexia D002100 21 associated lipids
Medulloblastoma D008527 22 associated lipids
Hyperinsulinism D006946 27 associated lipids
Alcoholism D000437 27 associated lipids
Hypothyroidism D007037 32 associated lipids
Heart Failure D006333 36 associated lipids
Starvation D013217 47 associated lipids
Fatty Liver D005234 48 associated lipids
Weight Loss D015431 56 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Per page 10 20 50 | Total 27

PubChem Associated disorders and diseases

What pathways are associated with Lmfa07050031

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

What functions are associated with Lmfa07050031?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lmfa07050031?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lmfa07050031

Download all related citations
Per page 10 20 50 100 | Total 787
Authors Title Published Journal PubMed Link
Klimov AN et al. [Formation of mevalonic acid, sterols and bile acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in the liver of rabbits with experimental hypercholesterolemia]. 1987 Biokhimiia pmid:2882784
Wakil SJ The relationship between structure and function for and the regulation of the enzymes of fatty acid synthesis. 1986 Ann. N. Y. Acad. Sci. pmid:2879500
De Spiegeleer B et al. Direct assay for phosphotransacetylase and acetyl-coenzyme A carboxylase by high-performance liquid chromatography. 1986 Anal. Biochem. pmid:2879484
Gonzalez-Rios MC et al. Lipid metabolism in biotin-responsive multiple carboxylase deficiency. 1985 J. Inherit. Metab. Dis. pmid:2878112
Wölfle K et al. On the mechanism of action of methylmalonyl-CoA mutase. Change of the steric course on isotope substitution. 1986 Eur. J. Biochem. pmid:2870921
Scholte HR et al. The source of malonyl-CoA in rat heart. The calcium paradox releases acetyl-CoA carboxylase and not propionyl-CoA carboxylase. 1986 FEBS Lett. pmid:2869975
Malewiak MI et al. Relationship between lipogenesis, ketogenesis, and malonyl-CoA content in isolated hepatocytes from the obese Zucker rat adapted to a high-fat diet. 1985 Metab. Clin. Exp. pmid:2861554
De Spiegeleer BM et al. High performance liquid chromatography stability study of malonyl-coenzyme A, using statistical experimental designs. 1989 Biomed. Chromatogr. pmid:2804428
Horie S et al. Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity. 1989 Arch. Biochem. Biophys. pmid:2774583
Rous S Possible contribution of [2-3H]malate and [2, 3-3h]succinate tritium to the same tritiated NADPH pool for participation in fatty acid synthesis. 1978 Biochimie pmid:27240
Guzmán M and Castro J Ethanol increases the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in short-term hepatocyte incubations. 1989 Biochim. Biophys. Acta pmid:2713390
Corkey BE et al. A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells. 1989 J. Biol. Chem. pmid:2689441
Jackowski S et al. Acetoacetyl-acyl carrier protein synthase. A target for the antibiotic thiolactomycin. 1989 J. Biol. Chem. pmid:2651445
Zammit VA et al. Target size analysis by radiation inactivation of carnitine palmitoyltransferase activity and malonyl-CoA binding in outer membranes from rat liver mitochondria. 1989 Biochem. J. pmid:2604707
Derrick JP and Ramsay RR L-carnitine acyltransferase in intact peroxisomes is inhibited by malonyl-CoA. 1989 Biochem. J. pmid:2590167
Thampy KG Formation of malonyl coenzyme A in rat heart. Identification and purification of an isozyme of A carboxylase from rat heart. 1989 J. Biol. Chem. pmid:2572585
Koyama Y et al. Effect of histamine H1-receptor antagonist on the regulation of carbohydrate and lipid metabolism in rat liver. 1989 Biochem. Int. pmid:2569872
Marsh EN et al. Subunit interactions in Propionibacterium shermanii methylmalonyl-CoA mutase studied by analytical ultracentrifugation. 1989 Biochem. J. pmid:2569862
Winder WW et al. Muscle malonyl-CoA decreases during exercise. 1989 J. Appl. Physiol. pmid:2558099
Takeyama N et al. Altered hepatic fatty acid metabolism in endotoxicosis: effect of L-carnitine on survival. 1989 Am. J. Physiol. pmid:2521428
Xu P et al. Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25049420
Dunn BJ et al. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases. 2014 Biochemistry pmid:24871074
Xu Y et al. Lipid accumulation is ahead of epithelial-to-mesenchymal transition and therapeutic intervention by acetyl-CoA carboxylase 2 silence in diabetic nephropathy. 2014 Metab. Clin. Exp. pmid:24650564
Bhatia H et al. miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. 2014 Biochim. Biophys. Acta pmid:24560669
Rock CO et al. Coupling of the biosynthesis of fatty acids and fatty alcohols. 1978 Arch. Biochem. Biophys. pmid:24423
Xu P et al. Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli. 2014 ACS Chem. Biol. pmid:24191643
Zabala D et al. Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus. 2013 Metab. Eng. pmid:24148183
Zhang M et al. The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylation. 2013 Mol. Cell. Biol. pmid:24081331
Liu C et al. Dissection of malonyl-coenzyme A reductase of Chloroflexus aurantiacus results in enzyme activity improvement. 2013 PLoS ONE pmid:24073271
Ghadiminejad I and Saggerson ED Carnitine palmitoyltransferase (CPT2) from liver mitochondrial inner membrane becomes inhibitable by malonyl-CoA if reconstituted with outer membrane malonyl-CoA binding protein. 1990 FEBS Lett. pmid:2401367
Bertoni G A key step in phlorotannin biosynthesis revealed. 2013 Plant Cell pmid:23995082
Gao S et al. Hypothalamic malonyl-CoA and the control of food intake. 2013 Physiol. Behav. pmid:23988346
Valsangkar D and Downs SM A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. 2013 Biol. Reprod. pmid:23863407
Musiol EM et al. The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. 2013 Chembiochem pmid:23828654
Vandhana S et al. Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors. 2013 Biochim. Biophys. Acta pmid:23816424
Kage H et al. An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. 2013 Chem. Biol. pmid:23790487
Guzmán M and Castro J Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal. 1990 Alcohol. Clin. Exp. Res. pmid:2378434
Gao S et al. Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23736540
Koyuncu E et al. Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. 2013 PLoS Pathog. pmid:23696731
Miura S et al. Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23695215
Gao S et al. Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei. 2013 Physiol. Behav. pmid:23680429
Bradbury I and Zammit VA An improved method for the analysis of data from radiation-inactivation studies. 1990 Anal. Biochem. pmid:2363496
Gokulan K et al. Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. 2013 J. Biol. Chem. pmid:23615910
Awakawa T et al. 4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. 2013 Chembiochem pmid:23609937
Lilly K et al. The medium-chain carnitine acyltransferase activity associated with rat liver microsomes is malonyl-CoA sensitive. 1990 Arch. Biochem. Biophys. pmid:2353818
Kimber NE et al. Skeletal muscle fat metabolism after exercise in humans: influence of fat availability. 2013 J. Appl. Physiol. pmid:23519231
Kerner J and Bieber L Isolation of a malonyl-CoA-sensitive CPT/beta-oxidation enzyme complex from heart mitochondria. 1990 Biochemistry pmid:2350540
Mercier R et al. Excess membrane synthesis drives a primitive mode of cell proliferation. 2013 Cell pmid:23452849
Pande SV et al. Freeze-thawing causes masking of membrane-bound outer carnitine palmitoyltransferase activity: implications for studies on carnitine palmitoyltransferases deficiency. 1990 Biochim. Biophys. Acta pmid:2344445
Rao G et al. Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production. 2013 Appl. Microbiol. Biotechnol. pmid:23358999
Tang X et al. Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae. 2013 Metab. Eng. pmid:23353549
Albanesi D et al. Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus. 2013 PLoS Pathog. pmid:23300457
Brass EP et al. Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat. 1990 Biochem. J. pmid:2327967
Zhabyeyev P et al. Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. 2013 Cardiovasc. Res. pmid:23257023
Derdak Z et al. Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. 2013 J. Hepatol. pmid:23211317
Fritz V et al. Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. 2013 Oncogene pmid:23208508
Knobloch M et al. Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. 2013 Nature pmid:23201681
Ellis JM and Wolfgang MJ A genetically encoded metabolite sensor for malonyl-CoA. 2012 Chem. Biol. pmid:23102226
Jeya M et al. A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency. 2012 Mol Biosyst pmid:23059854
Lewandowski ED et al. Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. 2013 Circ. Res. pmid:22982985
Foster DW Malonyl-CoA: the regulator of fatty acid synthesis and oxidation. 2012 J. Clin. Invest. pmid:22833869
Jung SY et al. Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells. 2012 J. Cell. Biochem. pmid:22786746
Kolwicz SC et al. Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. 2012 Circ. Res. pmid:22730442
Tokutake Y et al. Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. 2012 Biochem. Biophys. Res. Commun. pmid:22713453
Kolodziej MP and Zammit VA Sensitivity of inhibition of rat liver mitochondrial outer-membrane carnitine palmitoyltransferase by malonyl-CoA to chemical- and temperature-induced changes in membrane fluidity. 1990 Biochem. J. pmid:2268270
Glund S et al. Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db mice. 2012 Diabetologia pmid:22532389
Moore RG et al. Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. 2012 PLoS ONE pmid:22509304
Iio W et al. Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. 2012 Biochem. Biophys. Res. Commun. pmid:22503976
Jensen K et al. Polyketide proofreading by an acyltransferase-like enzyme. 2012 Chem. Biol. pmid:22444588
Ussher JR et al. Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. 2012 Cardiovasc. Res. pmid:22436846
Ghadiminejad I and Saggerson ED The relationship of rat liver overt carnitine palmitoyltransferase to the mitochondrial malonyl-CoA binding entity and to the latent palmitoyltransferase. 1990 Biochem. J. pmid:2241911
Chen Q et al. Fatty acid synthase inhibitors separated from oiltea camellia by high-speed counter-current chromatography. 2011 Jun-Jul J. Food Sci. pmid:22417422
Guo H et al. Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells. 2012 Lipids Health Dis pmid:22243683
Cherbuy C et al. Oleate metabolism in pig enterocytes is characterized by an increased oxidation rate in the presence of a high esterification rate within two days after birth. 2012 J. Nutr. pmid:22223579
Natarajan S et al. Crystal structure of malonyl CoA-Acyl carrier protein transacylase from Xanthomanous oryzae pv. oryzae and its proposed binding with ACP. 2012 Mol. Cells pmid:22134719
Wolkowicz PE and Wood JM Effect of malonyl-CoA on calcium uptake and pyridine nucleotide redox state in rat liver mitochondria. 1979 FEBS Lett. pmid:221253
Zhang X et al. Improving fatty acid production in Escherichia coli through the overexpression of malonyl coA-acyl carrier protein transacylase. 2012 Jan-Feb Biotechnol. Prog. pmid:22038854
Smith AC and Cronan JE Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo. 2012 J. Bacteriol. pmid:22037404
Morash AJ and McClelland GB Regulation of carnitine palmitoyltransferase (CPT) I during fasting in rainbow trout (Oncorhynchus mykiss) promotes increased mitochondrial fatty acid oxidation. 2011 Nov-Dec Physiol. Biochem. Zool. pmid:22030855
Gnoni GV et al. [Effect of nutritional changes on fatty acid synthesis in rat liver microsomes. Role of cyclic AMP]. 1978 Boll. Soc. Ital. Biol. Sper. pmid:219874
Naganuma T et al. Biochemical characterization of the very long-chain fatty acid elongase ELOVL7. 2011 FEBS Lett. pmid:21959040
Jenei ZA et al. Packing of transmembrane domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and malonyl-CoA sensitivity of the mitochondrial outer membrane protein. 2011 FASEB J. pmid:21917985
Keung W et al. Chronic central leptin decreases food intake and improves glucose tolerance in diet-induced obese mice independent of hypothalamic malonyl CoA levels and skeletal muscle insulin sensitivity. 2011 Endocrinology pmid:21914780
Wheeler PR et al. Enzymes for biosynthesis de novo and elongation of fatty acids in mycobacteria grown in host cells: is Mycobacterium leprae competent in fatty acid biosynthesis? 1990 J. Gen. Microbiol. pmid:2191079
Serviddio G et al. Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet. 2011 PLoS ONE pmid:21909411
Jia Y and Zhong JJ Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosum. 2011 Bioresour. Technol. pmid:21907573
Hammerbacher A et al. Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection. 2011 Plant Physiol. pmid:21865488
Kudej RK et al. Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. 2011 Cardiovasc. Res. pmid:21835931
McGarry JD et al. Carnitine palmitoyltransferase--structure/function/regulatory relationships. 1990 Prog. Clin. Biol. Res. pmid:2183232
Xu P et al. Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA. 2011 Metab. Eng. pmid:21763447
Rathnasingh C et al. Production of 3-hydroxypropionic acid via malonyl-CoA pathway using recombinant Escherichia coli strains. 2012 J. Biotechnol. pmid:21723339
Alves J et al. Cloning, expression, and enzymatic activity of Acinetobacter baumannii and Klebsiella pneumoniae acetyl-coenzyme A carboxylases. 2011 Anal. Biochem. pmid:21704013
Prip-Buus C et al. Evidence that the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA is an important site of regulation of hepatic fatty acid oxidation in the fetal and newborn rabbit. Perinatal development and effects of pancreatic hormones in cultured rabbit hepatocytes. 1990 Biochem. J. pmid:2167069
Winder WW et al. Time course of exercise-induced decline in malonyl-CoA in different muscle types. 1990 Am. J. Physiol. pmid:2166437
Gao S et al. Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21593415
Reamy AA and Wolfgang MJ Carnitine palmitoyltransferase-1c gain-of-function in the brain results in postnatal microencephaly. 2011 J. Neurochem. pmid:21592121
Bengtsson C et al. Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats. 2011 Bioorg. Med. Chem. pmid:21515056
Lauzier B et al. Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart. 2011 J. Mol. Cell. Cardiol. pmid:21510957
Gao S et al. Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21508288
Gilibili RR et al. Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of acetyl-CoA and malonyl-CoA in animal tissues. 2011 Biomed. Chromatogr. pmid:21381064