Dunn BJ et al. |
Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases. |
2014 |
Biochemistry |
pmid:24871074
|
Xu P et al. |
Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. |
2014 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25049420
|
Xu P et al. |
Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli. |
2014 |
ACS Chem. Biol. |
pmid:24191643
|
Xu Y et al. |
Lipid accumulation is ahead of epithelial-to-mesenchymal transition and therapeutic intervention by acetyl-CoA carboxylase 2 silence in diabetic nephropathy. |
2014 |
Metab. Clin. Exp. |
pmid:24650564
|
Bhatia H et al. |
miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. |
2014 |
Biochim. Biophys. Acta |
pmid:24560669
|
Lewandowski ED et al. |
Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. |
2013 |
Circ. Res. |
pmid:22982985
|
Mercier R et al. |
Excess membrane synthesis drives a primitive mode of cell proliferation. |
2013 |
Cell |
pmid:23452849
|
Kage H et al. |
An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. |
2013 |
Chem. Biol. |
pmid:23790487
|
Vandhana S et al. |
Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors. |
2013 |
Biochim. Biophys. Acta |
pmid:23816424
|
Musiol EM et al. |
The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. |
2013 |
Chembiochem |
pmid:23828654
|
Awakawa T et al. |
4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. |
2013 |
Chembiochem |
pmid:23609937
|
Gokulan K et al. |
Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. |
2013 |
J. Biol. Chem. |
pmid:23615910
|
Miura S et al. |
Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. |
2013 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:23695215
|
Koyuncu E et al. |
Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. |
2013 |
PLoS Pathog. |
pmid:23696731
|
Gao S et al. |
Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei. |
2013 |
Physiol. Behav. |
pmid:23680429
|
Albanesi D et al. |
Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus. |
2013 |
PLoS Pathog. |
pmid:23300457
|
Zhabyeyev P et al. |
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. |
2013 |
Cardiovasc. Res. |
pmid:23257023
|
Knobloch M et al. |
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis. |
2013 |
Nature |
pmid:23201681
|
Fritz V et al. |
Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. |
2013 |
Oncogene |
pmid:23208508
|
Derdak Z et al. |
Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. |
2013 |
J. Hepatol. |
pmid:23211317
|
Tang X et al. |
Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae. |
2013 |
Metab. Eng. |
pmid:23353549
|
Rao G et al. |
Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production. |
2013 |
Appl. Microbiol. Biotechnol. |
pmid:23358999
|
Kimber NE et al. |
Skeletal muscle fat metabolism after exercise in humans: influence of fat availability. |
2013 |
J. Appl. Physiol. |
pmid:23519231
|
Gao S et al. |
Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake. |
2013 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:23736540
|
Liu C et al. |
Dissection of malonyl-coenzyme A reductase of Chloroflexus aurantiacus results in enzyme activity improvement. |
2013 |
PLoS ONE |
pmid:24073271
|
Zhang M et al. |
The yeast AMPK homolog SNF1 regulates acetyl coenzyme A homeostasis and histone acetylation. |
2013 |
Mol. Cell. Biol. |
pmid:24081331
|
Gao S et al. |
Hypothalamic malonyl-CoA and the control of food intake. |
2013 |
Physiol. Behav. |
pmid:23988346
|
Bertoni G |
A key step in phlorotannin biosynthesis revealed. |
2013 |
Plant Cell |
pmid:23995082
|
Valsangkar D and Downs SM |
A requirement for fatty acid oxidation in the hormone-induced meiotic maturation of mouse oocytes. |
2013 |
Biol. Reprod. |
pmid:23863407
|
Zabala D et al. |
Engineering precursor metabolite pools for increasing production of antitumor mithramycins in Streptomyces argillaceus. |
2013 |
Metab. Eng. |
pmid:24148183
|
Zhang X et al. |
Improving fatty acid production in Escherichia coli through the overexpression of malonyl coA-acyl carrier protein transacylase. |
2012 Jan-Feb |
Biotechnol. Prog. |
pmid:22038854
|
Albaugh VL et al. |
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents. |
2012 |
Schizophr Bull |
pmid:20494946
|
Natarajan S et al. |
Crystal structure of malonyl CoA-Acyl carrier protein transacylase from Xanthomanous oryzae pv. oryzae and its proposed binding with ACP. |
2012 |
Mol. Cells |
pmid:22134719
|
Smith AC and Cronan JE |
Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity in vivo. |
2012 |
J. Bacteriol. |
pmid:22037404
|
Rathnasingh C et al. |
Production of 3-hydroxypropionic acid via malonyl-CoA pathway using recombinant Escherichia coli strains. |
2012 |
J. Biotechnol. |
pmid:21723339
|
Glund S et al. |
Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db mice. |
2012 |
Diabetologia |
pmid:22532389
|
Guo H et al. |
Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells. |
2012 |
Lipids Health Dis |
pmid:22243683
|
Cherbuy C et al. |
Oleate metabolism in pig enterocytes is characterized by an increased oxidation rate in the presence of a high esterification rate within two days after birth. |
2012 |
J. Nutr. |
pmid:22223579
|
Tokutake Y et al. |
Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22713453
|
Jung SY et al. |
Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells. |
2012 |
J. Cell. Biochem. |
pmid:22786746
|
Kolwicz SC et al. |
Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. |
2012 |
Circ. Res. |
pmid:22730442
|
Iio W et al. |
Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. |
2012 |
Biochem. Biophys. Res. Commun. |
pmid:22503976
|
Jensen K et al. |
Polyketide proofreading by an acyltransferase-like enzyme. |
2012 |
Chem. Biol. |
pmid:22444588
|
Ussher JR et al. |
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. |
2012 |
Cardiovasc. Res. |
pmid:22436846
|
Foster DW |
Malonyl-CoA: the regulator of fatty acid synthesis and oxidation. |
2012 |
J. Clin. Invest. |
pmid:22833869
|
Ellis JM and Wolfgang MJ |
A genetically encoded metabolite sensor for malonyl-CoA. |
2012 |
Chem. Biol. |
pmid:23102226
|
Jeya M et al. |
A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency. |
2012 |
Mol Biosyst |
pmid:23059854
|
Moore RG et al. |
Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. |
2012 |
PLoS ONE |
pmid:22509304
|
Morash AJ and McClelland GB |
Regulation of carnitine palmitoyltransferase (CPT) I during fasting in rainbow trout (Oncorhynchus mykiss) promotes increased mitochondrial fatty acid oxidation. |
2011 Nov-Dec |
Physiol. Biochem. Zool. |
pmid:22030855
|
Chen Q et al. |
Fatty acid synthase inhibitors separated from oiltea camellia by high-speed counter-current chromatography. |
2011 Jun-Jul |
J. Food Sci. |
pmid:22417422
|