Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.
To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Lmfa07050031
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Revill WP et al. | Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant. | 1995 | J. Bacteriol. | pmid:7608065 |
Prentki M and Corkey BE | Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? | 1996 | Diabetes | pmid:8593930 |
Odland LM et al. | Human skeletal muscle malonyl-CoA at rest and during prolonged submaximal exercise. | 1996 | Am. J. Physiol. | pmid:8638703 |
Kurosaki F | Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot. | 1996 | Arch. Biochem. Biophys. | pmid:8638933 |
Kurowski TG et al. | Malonyl coenzyme A and adiposity in the Dahl salt-sensitive rat: effects of pioglitazone. | 1996 | Metab. Clin. Exp. | pmid:8609842 |
Kurosaki F | Transacylase-like structure and its role in substrate channeling of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cell extracts. | 1996 | FEBS Lett. | pmid:8566239 |
Heath RJ and Rock CO | Regulation of fatty acid elongation and initiation by acyl-acyl carrier protein in Escherichia coli. | 1996 | J. Biol. Chem. | pmid:8567624 |
Helariutta Y et al. | Duplication and functional divergence in the chalcone synthase gene family of Asteraceae: evolution with substrate change and catalytic simplification. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8799149 |
Winder WW and Hardie DG | Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. | 1996 | Am. J. Physiol. | pmid:8779952 |
Child CJ et al. | Structural similarities between 6-methylsalicylic acid synthase from Penicillium patulum and vertebrate type I fatty acid synthase: evidence from thiol modification studies. | 1996 | Biochemistry | pmid:8823160 |
Civelek VN et al. | Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP. | 1996 | Biochem. J. | pmid:8809055 |
Moré MI et al. | Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. | 1996 | Science | pmid:8658141 |
Fraser F et al. | Evidence that both the acyl-CoA- and malonyl-CoA binding sites of mitochondrial overt carnitine palmitoyltransferase (CPT I) are exposed on the cytosolic face of the outer membrane. | 1996 | Biochem. Soc. Trans. | pmid:8736842 |
Wang D et al. | Acetyl coenzyme A carboxylase activity in neonatal rat cardiac myocytes in culture: citrate dependence and effects of hypoxia. | 1996 | Arch. Biochem. Biophys. | pmid:8561504 |
Brun T et al. | Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling. | 1996 | Diabetes | pmid:8549864 |
Matschinsky FM | Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. | 1996 | Diabetes | pmid:8549869 |
Drynan L et al. | The role of changes in the sensitivity of hepatic mitochondrial overt carnitine palmitoyltransferase in determining the onset of the ketosis of starvation in the rat. | 1996 | Biochem. J. | pmid:8836117 |
Rangan VS and Smith S | Expression in Escherichia coli and refolding of the malonyl-/acetyltransferase domain of the multifunctional animal fatty acid synthase. | 1996 | J. Biol. Chem. | pmid:8940200 |
Hall JL et al. | Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels. | 1996 | Cardiovasc. Res. | pmid:8944819 |
McCormack JG et al. | Effects of ranolazine on oxidative substrate preference in epitrochlearis muscle. | 1996 | J. Appl. Physiol. | pmid:8872662 |
Kuhstoss S et al. | Production of a novel polyketide through the construction of a hybrid polyketide synthase. | 1996 | Gene | pmid:8996112 |
Brown NF et al. | Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. | 1997 | Biochem. J. | pmid:9355756 |
Roughan PG | Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase. | 1997 | Biochem. J. | pmid:9355762 |
Prentki M et al. | Signal transduction mechanisms in nutrient-induced insulin secretion. | 1997 | Diabetologia | pmid:9248699 |
Ruderman NB et al. | Lipid abnormalities in muscle of insulin-resistant rodents. The malonyl CoA hypothesis. | 1997 | Ann. N. Y. Acad. Sci. | pmid:9329757 |
Oakes ND et al. | Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. | 1997 | Diabetes | pmid:9392490 |
Rasmussen BB and Winder WW | Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase. | 1997 | J. Appl. Physiol. | pmid:9338417 |
Power GW and Newsholme EA | Dietary fatty acids influence the activity and metabolic control of mitochondrial carnitine palmitoyltransferase I in rat heart and skeletal muscle. | 1997 | J. Nutr. | pmid:9349840 |
Zammit VA et al. | Regulation of mitochondrial outer-membrane carnitine palmitoyltransferase (CPT I): role of membrane-topology. | 1997 | Adv. Enzyme Regul. | pmid:9381976 |
Hutber CA et al. | Endurance training attenuates the decrease in skeletal muscle malonyl-CoA with exercise. | 1997 | J. Appl. Physiol. | pmid:9390963 |
Merrill GF et al. | AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. | 1997 | Am. J. Physiol. | pmid:9435525 |
Fraser F et al. | Topology of carnitine palmitoyltransferase I in the mitochondrial outer membrane. | 1997 | Biochem. J. | pmid:9169604 |
Preisig-Müller R et al. | Plant polyketide synthases leading to stilbenoids have a domain catalyzing malonyl-CoA:CO2 exchange, malonyl-CoA decarboxylation, and covalent enzyme modification and a site for chain lengthening. | 1997 | Biochemistry | pmid:9204882 |
de Vries Y et al. | Functional characterization of mitochondrial carnitine palmitoyltransferases I and II expressed in the yeast Pichia pastoris. | 1997 | Biochemistry | pmid:9136891 |
Rangan VS and Smith S | Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue. | 1997 | J. Biol. Chem. | pmid:9115261 |
Hutber CA et al. | Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase. | 1997 | Am. J. Physiol. | pmid:9124333 |
Chohnan S et al. | Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. | 1997 | Appl. Environ. Microbiol. | pmid:9023936 |
Velasco G et al. | Control of hepatic fatty acid oxidation by 5'-AMP-activated protein kinase involves a malonyl-CoA-dependent and a malonyl-CoA-independent mechanism. | 1997 | Arch. Biochem. Biophys. | pmid:9016810 |
Maurer I and Zierz S | Carnitine palmitoyltransferase in patients with cardiac ischemia due to atherosclerotic coronary artery disease and in patients with idiopathic dilated cardiomyopathy. | 1997 May-Jun | Cardiology | pmid:9129847 |
Carreras CW and Khosla C | Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase. | 1998 | Biochemistry | pmid:9518007 |
Blázquez C et al. | Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes. | 1998 | J. Neurochem. | pmid:9751193 |
Goodwin GW et al. | Regulation of energy metabolism of the heart during acute increase in heart work. | 1998 | J. Biol. Chem. | pmid:9792661 |
Cohen I et al. | The N-terminal domain of rat liver carnitine palmitoyltransferase 1 mediates import into the outer mitochondrial membrane and is essential for activity and malonyl-CoA sensitivity. | 1998 | J. Biol. Chem. | pmid:9792707 |
Swanson ST et al. | Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues. | 1998 | Biochem. J. | pmid:9794789 |
Hunter SC and Ohlrogge JB | Regulation of spinach chloroplast acetyl-CoA carboxylase. | 1998 | Arch. Biochem. Biophys. | pmid:9808758 |
Rangan VS et al. | Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits. | 1998 | J. Biol. Chem. | pmid:9857025 |
Ruderman NB and Dean D | Malonyl CoA, long chain fatty acyl CoA and insulin resistance in skeletal muscle. | 1998 | J Basic Clin Physiol Pharmacol | pmid:10212840 |
Chohnan S et al. | Changes in size of intracellular pools of coenzyme A and its thioesters in Escherichia coli K-12 cells to various carbon sources and stresses. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9692193 |
Shi J et al. | Deletion of the conserved first 18 N-terminal amino acid residues in rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA sensitivity and binding. | 1998 | Biochemistry | pmid:9692998 |
Alam N and Saggerson ED | Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. | 1998 | Biochem. J. | pmid:9693125 |
Odland LM et al. | Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans. | 1998 | Am. J. Physiol. | pmid:9611159 |
Zammit VA et al. | Lipid molecular order in liver mitochondrial outer membranes, and sensitivity of carnitine palmitoyltransferase I to malonyl-CoA. | 1998 | Lipids | pmid:9590624 |
Mukherjee S and Katiyar SS | Inactivation of enoyl-CoA reductase in pigeon liver fatty acid synthetase by pyridoxal 5'-phosphate: evidence for the presence of one lysine residue at the active site. | 1998 | J. Enzym. Inhib. | pmid:9629539 |
Antinozzi PA et al. | Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. | 1998 | J. Biol. Chem. | pmid:9632669 |
Velasco G et al. | Malonyl-CoA-independent acute control of hepatic carnitine palmitoyltransferase I activity. Role of Ca2+/calmodulin-dependent protein kinase II and cytoskeletal components. | 1998 | J. Biol. Chem. | pmid:9705278 |
Holness MJ et al. | Impact of protein restriction on the regulation of cardiac carnitine palmitoyltransferase by malonyl-CoA. | 1998 | J. Mol. Cell. Cardiol. | pmid:9710806 |
Roche E et al. | Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression. | 1998 | Diabetes | pmid:9648832 |
Maurer I et al. | Carnitine acyltransferases are not changed in Alzheimer disease. | 1998 | Alzheimer Dis Assoc Disord | pmid:9651134 |
Hoppel CL et al. | The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria. | 1998 | J. Biol. Chem. | pmid:9722587 |
Winder WW | Malonyl-CoA--regulator of fatty acid oxidation in muscle during exercise. | 1998 | Exerc Sport Sci Rev | pmid:9696987 |
Anderson RC | Carnitine palmitoyltransferase: a viable target for the treatment of NIDDM? | 1998 | Curr. Pharm. Des. | pmid:10197030 |
Velasco G et al. | Evidence that the AMP-activated protein kinase stimulates rat liver carnitine palmitoyltransferase I by phosphorylating cytoskeletal components. | 1998 | FEBS Lett. | pmid:9845345 |
Rasmussen BB et al. | Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase. | 1998 | J. Appl. Physiol. | pmid:9804562 |
Merrill GF et al. | Influence of malonyl-CoA and palmitate concentration on rate of palmitate oxidation in rat muscle. | 1998 | J. Appl. Physiol. | pmid:9804598 |
Ruderman NB et al. | Malonyl CoA as a metabolic switch and a regulator of insulin sensitivity. | 1998 | Adv. Exp. Med. Biol. | pmid:9781332 |
Zhang S and Kim KH | Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. | 1998 | Cell. Signal. | pmid:9502115 |
Adams SH et al. | Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat. | 1998 | Biol. Reprod. | pmid:9828184 |
Fernandes ND and Kolattukudy PE | A newly identified methyl-branched chain fatty acid synthesizing enzyme from Mycobacterium tuberculosis var. bovis BCG. | 1998 | J. Biol. Chem. | pmid:9446591 |
Wang D et al. | The liver isoform of carnitine palmitoyltransferase I is activated in neonatal rat cardiac myocytes by hypoxia. | 1998 | Mol. Cell. Biochem. | pmid:9546643 |
Skelly RH et al. | A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. | 1998 | Biochem. J. | pmid:9531497 |
McGarry JD | Glucose-fatty acid interactions in health and disease. | 1998 | Am. J. Clin. Nutr. | pmid:9497160 |
Hitchman TS et al. | Catalytic self-acylation of type II polyketide synthase acyl carrier proteins. | 1998 | Chem. Biol. | pmid:9479478 |
Child CJ and Shoolingin-Jordan PM | Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. | 1998 | Biochem. J. | pmid:9480912 |
Jackson VN et al. | Sequencing and functional expression of the malonyl-CoA-sensitive carnitine palmitoyltransferase from Drosophila melanogaster. | 1999 | Biochem. J. | pmid:10417309 |
Bao W et al. | The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide. | 1999 | J. Bacteriol. | pmid:10419974 |
Zhou P et al. | Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. | 1999 | Chem. Biol. | pmid:10421763 |
Sugden MC et al. | Hyperthyroidism facilitates cardiac fatty acid oxidation through altered regulation of cardiac carnitine palmitoyltransferase: studies in vivo and with cardiac myocytes. | 1999 | Horm. Metab. Res. | pmid:10422724 |
Kozaki A and Sasaki Y | Light-dependent changes in redox status of the plastidic acetyl-CoA carboxylase and its regulatory component. | 1999 | Biochem. J. | pmid:10215591 |
Saha AK et al. | Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. | 1999 | Am. J. Physiol. | pmid:10362615 |
Kantor PF et al. | Fatty acid oxidation in the reperfused ischemic heart. | 1999 | Am. J. Med. Sci. | pmid:10408755 |
Shi J et al. | A single amino acid change (substitution of glutamate 3 with alanine) in the N-terminal region of rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA inhibition and high affinity binding. | 1999 | J. Biol. Chem. | pmid:10092622 |
Blázquez C et al. | The stimulation of ketogenesis by cannabinoids in cultured astrocytes defines carnitine palmitoyltransferase I as a new ceramide-activated enzyme. | 1999 | J. Neurochem. | pmid:10098887 |
Goodwin GW and Taegtmeyer H | Regulation of fatty acid oxidation of the heart by MCD and ACC during contractile stimulation. | 1999 | Am. J. Physiol. | pmid:10516138 |
Funa N et al. | A new pathway for polyketide synthesis in microorganisms. | 1999 | Nature | pmid:10476972 |
Sargueil F et al. | High metabolism and subsequent elongation of 3-hydroxyeicosanoyl-CoA in very-long-chain fatty acid deficient PNS of Trembler mice. | 1999 | Neurosci. Lett. | pmid:10505644 |
Zammit VA | The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function. | 1999 | Biochem. J. | pmid:10527927 |
Dreier J et al. | Kinetic analysis of the actinorhodin aromatic polyketide synthase. | 1999 | J. Biol. Chem. | pmid:10455191 |
Sleboda J et al. | Short-term regulation of carnitine palmitoyltransferase I in cultured rat hepatocytes: spontaneous inactivation and reactivation by fatty acids. | 1999 | Biochim. Biophys. Acta | pmid:9989283 |
Ruderman NB et al. | Malonyl-CoA, fuel sensing, and insulin resistance. | 1999 | Am. J. Physiol. | pmid:9886945 |
Menendez C et al. | Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation. | 1999 | J. Bacteriol. | pmid:9973333 |
Laybutt DR et al. | Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat. | 1999 | Am. J. Physiol. | pmid:10600797 |
Richardson MT et al. | Tolerance and specificity of recombinant 6-methylsalicyclic acid synthase. | 1999 | Metab. Eng. | pmid:10935930 |
Abo-Hashema KA et al. | Liver mitochondria, confirmed as intact by complete suppression of succinate uptake and oxidation, possess a carnitine palmitoyltransferase I that is totally inhibited by malonyl CoA. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10329463 |
Hertel K et al. | Kinetic investigation of carnitine palmitoyltransferases in homogenates of human skeletal muscle using L-amino-carnitine and malonyl-CoA. | 1999 | Adv. Exp. Med. Biol. | pmid:10709631 |
Guertl B et al. | Metabolic cardiomyopathies. | 2000 | Int J Exp Pathol | pmid:11298185 |
Suh DY et al. | Evidence for catalytic cysteine-histidine dyad in chalcone synthase. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10973790 |
Domergue F et al. | Purification of the acyl-CoA elongase complex from developing rapeseed and characterization of the 3-ketoacyl-CoA synthase and the 3-hydroxyacyl-CoA dehydratase. | 2000 | Lipids | pmid:10907783 |
BÃ¥venholm PN et al. | Fatty acid oxidation and the regulation of malonyl-CoA in human muscle. | 2000 | Diabetes | pmid:10909961 |
McGarry JD and Brown NF | Reconstitution of purified, active and malonyl-CoA-sensitive rat liver carnitine palmitoyltransferase I: relationship between membrane environment and malonyl-CoA sensitivity. | 2000 | Biochem. J. | pmid:10861226 |
Dean D et al. | Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. | 2000 | Diabetes | pmid:10923628 |