Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.
To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Lmfa07050031
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Brown NF et al. | Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes. | 1997 | Biochem. J. | pmid:9355756 |
Roughan PG | Stromal concentrations of coenzyme A and its esters are insufficient to account for rates of chloroplast fatty acid synthesis: evidence for substrate channelling within the chloroplast fatty acid synthase. | 1997 | Biochem. J. | pmid:9355762 |
Alam N and Saggerson ED | Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle. | 1998 | Biochem. J. | pmid:9693125 |
A'Bháird NN and Ramsay RR | Malonyl-CoA inhibition of peroxisomal carnitine octanoyltransferase. | 1992 | Biochem. J. | pmid:1530596 |
Ghadiminejad I and Saggerson ED | The relationship of rat liver overt carnitine palmitoyltransferase to the mitochondrial malonyl-CoA binding entity and to the latent palmitoyltransferase. | 1990 | Biochem. J. | pmid:2241911 |
Moir AM and Zammit VA | Monitoring of changes in hepatic fatty acid and glycerolipid metabolism during the starved-to-fed transition in vivo. Studies on awake, unrestrained rats. | 1993 | Biochem. J. | pmid:8424771 |
Mills SE et al. | Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I. | 1984 | Biochem. J. | pmid:6743235 |
Rendina AR and Cheng D | Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates. | 2005 | Biochem. J. | pmid:15715522 |
Jones AV et al. | Inhibition of plant fatty acid synthesis by nitroimidazoles. | 1981 | Biochem. J. | pmid:7325993 |
Cook GA | Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA. | 1984 | Biochem. J. | pmid:6525169 |
Bird MI et al. | Carnitine acyltransferase activities in rat brain mitochondria. Bimodal distribution, kinetic constants, regulation by malonyl-CoA and developmental pattern. | 1985 | Biochem. J. | pmid:3977877 |
Mills SE et al. | Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I. | 1983 | Biochem. J. | pmid:6615474 |
Zammit VA | Reversible sensitization and desensitization of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in isolated rat liver mitochondria. Significance for the mechanism of malonyl-CoA-induced sensitization. | 1983 | Biochem. J. | pmid:6626153 |
McCormick K et al. | Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidation. | 1983 | Biochem. J. | pmid:6661211 |
Lee GY et al. | Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. | 2004 | Biochem. J. | pmid:14641110 |
Zammit VA and Corstorphine CG | Altered release of carnitine palmitoyltransferase activity by digitonin from liver mitochondria of rats in different physiological states. | 1985 | Biochem. J. | pmid:4052052 |
Zammit VA | Increased sensitivity of carnitine palmitoyltransferase I activity to malonyl-CoA inhibition after preincubation of intact rat liver mitochondria with micromolar concentrations of malonyl-CoA in vitro. | 1983 | Biochem. J. | pmid:6870813 |
Zammit VA and Corstorphine CG | Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria. | 1985 | Biochem. J. | pmid:4062901 |
Stephens TW et al. | Effect of pH on malonyl-CoA inhibition of carnitine palmitoyltransferase I. | 1983 | Biochem. J. | pmid:6882380 |
Brady LJ et al. | Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation. | 1985 | Biochem. J. | pmid:4091801 |
Skelly RH et al. | A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. | 1998 | Biochem. J. | pmid:9531497 |
Child CJ and Shoolingin-Jordan PM | Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. | 1998 | Biochem. J. | pmid:9480912 |
Koyama Y et al. | Effect of histamine H1-receptor antagonist on the regulation of carbohydrate and lipid metabolism in rat liver. | 1989 | Biochem. Int. | pmid:2569872 |
Lane MD and Cha SH | Effect of glucose and fructose on food intake via malonyl-CoA signaling in the brain. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19265677 |
Rutkoski A and Jaworski JG | Fatty acid synthetase from chloroplasts of soybean cotyledons: ACP activation and CoA inhibition. | 1978 | Biochem. Biophys. Res. Commun. | pmid:718691 |
Cha SH and Lane MD | Central lactate metabolism suppresses food intake via the hypothalamic AMP kinase/malonyl-CoA signaling pathway. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19523445 |
White JS | Significance of differential effects of glucose and fructose on brain food signaling is uncertain. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19785993 |
Kashfi K et al. | Effects of cholesterol loading of mouse macrophages on carnitine palmitoyltransferase activity and sensitivity to inhibition by malonyl-CoA. | 1991 | Biochem. Biophys. Res. Commun. | pmid:2059202 |
Thupari JN et al. | Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11444828 |
Eaton S et al. | Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11444876 |
Kashfi K and Cook GA | Malonyl-CoA inhibits proteolysis of carnitine palmitoyltransferase. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1859420 |
Oguro S et al. | Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15530429 |
Nicot C et al. | C75 activates malonyl-CoA sensitive and insensitive components of the CPT system. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15541339 |
Saito K et al. | Differential hydrogen exchange during the fatty acid synthetase reaction: deuterium distribution of fatty acids synthesized from [2-2H2]malonyl-CoA. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6758778 |
Dai J et al. | Leucine-764 near the extreme C-terminal end of carnitine palmitoyltransferase I is important for activity. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12565845 |
Saha AK et al. | AMPK regulation of the growth of cultured human keratinocytes. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16949049 |
Srinivasan KR and Kumar S | Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7247949 |
Guzmán M and Geelen MJ | Short-term inhibition of carnitine palmitoyltransferase I activity in rat hepatocytes incubated with ethanol. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3401227 |
Knudsen J and Grunnet I | Primer specificity of mammalian mammary gland fatty acid synthetases. | 1980 | Biochem. Biophys. Res. Commun. | pmid:7417345 |
Cook GA et al. | Feeding of lovastatin to rats increases the activity of the hepatic mitochondrial outer carnitine palmitoyltransferase. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3342059 |
Guzmán M et al. | Ethanol feeding to rats reversibly decreases hepatic carnitine palmitoyltransferase activity and increases enzyme sensitivity to malonyl-CoA. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3426584 |
Suh DY et al. | Evidence for catalytic cysteine-histidine dyad in chalcone synthase. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10973790 |
Abo-Hashema KA et al. | Liver mitochondria, confirmed as intact by complete suppression of succinate uptake and oxidation, possess a carnitine palmitoyltransferase I that is totally inhibited by malonyl CoA. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10329463 |
Tokutake Y et al. | Effect of diet composition on coenzyme A and its thioester pools in various rat tissues. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22713453 |
Iio W et al. | Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22503976 |
Peñas M and Benito M | Regulation of carnitine palmitoyltransferase activity in the liver and brown adipose tissue in the newborn rat: effect of starvation and hypothermia. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3964261 |
Saha AK et al. | Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo. | 2004 | Biochem. Biophys. Res. Commun. | pmid:14733947 |
Tokutake Y et al. | Coenzyme A and its thioester pools in fasted and fed rat tissues. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20933504 |
Kariya T and Wille LJ | Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid). | 1978 | Biochem. Biophys. Res. Commun. | pmid:637858 |
Ussher JR and Lopaschuk GD | Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion. | 2009 | Basic Res. Cardiol. | pmid:19242641 |
Liu Y et al. | Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening. | 2007 | Assay Drug Dev Technol | pmid:17477831 |
Weiss DR and Glickman JF | Characterization of fatty acid synthase activity using scintillation proximity. | 2003 | Assay Drug Dev Technol | pmid:15090142 |
Kerner J et al. | Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: effect of starvation. | 2008 | Arch. Physiol. Biochem. | pmid:18629681 |
VorÃsek J and Rehácek Z | Fine structural localization of alkaloid synthesis in endoplasmic reticulum of submerged Claviceps purpurea. | 1978 | Arch. Microbiol. | pmid:29585 |
Morita N et al. | Synthesis in vitro of very long chain fatty acids in Vibrio sp. strain ABE-1. | 1992 | Arch. Microbiol. | pmid:1510554 |
Murad S and Kishimoto Y | Chain elongation of fatty acid in brain: a comparison of mitochondrial and microsomal enzyme activities. | 1978 | Arch. Biochem. Biophys. | pmid:626498 |
Buckner JS et al. | Synthesis of multimethyl-branched fatty acids by avian and mammalian fatty acid synthetase and its regulation by malonyl-CoA decarboxylase in the uropygial gland. | 1978 | Arch. Biochem. Biophys. | pmid:629531 |
Ludwig SA and Sprecher H | Substrate specificity studies on the malonyl-CoA-dependent chain elongation of all-cis polyunsaturated fatty acids by rat liver microsomes. | 1979 | Arch. Biochem. Biophys. | pmid:543721 |
Cassagne C and Lessire R | Biosynthesis of saturated very long chain fatty acids by purified membrane fractions from leek epidermal cells. | 1978 | Arch. Biochem. Biophys. | pmid:736558 |
Rock CO et al. | Coupling of the biosynthesis of fatty acids and fatty alcohols. | 1978 | Arch. Biochem. Biophys. | pmid:24423 |
Hunter SC and Ohlrogge JB | Regulation of spinach chloroplast acetyl-CoA carboxylase. | 1998 | Arch. Biochem. Biophys. | pmid:9808758 |
Kim YS et al. | Malonyl-CoA decarboxylase from Mycobacterium tuberculosis and Pseudomonas fluorescens. | 1979 | Arch. Biochem. Biophys. | pmid:114118 |
Kim YS and Kolattukudy PE | Purification and properties of malonyl-CoA decarboxylase from rat liver mitochondria and its immunological comparison with the enzymes from rat brain, heart, and mammary gland. | 1978 | Arch. Biochem. Biophys. | pmid:101148 |
Kim YS and Kolattukudy PE | Malonyl-CoA decarboxylase from the uropygial gland of waterfowl: purification, properties, immunological comparison, and role in regulating the synthesis of multimethyl-branched fatty acids. | 1978 | Arch. Biochem. Biophys. | pmid:102255 |
Ahmad PM and Ahmad F | Effect of citrate on the different reactions catalyzed by rat mammary gland acetyl CoA carboxylase. | 1983 | Arch. Biochem. Biophys. | pmid:6130749 |
Willard HF and Rosenberg LE | Interactions of methylmalonyl CoA mutase from normal human fibroblasts with adenosylcobalamin and methylmalonyl CoA: evidence for non-equivalent active sites. | 1980 | Arch. Biochem. Biophys. | pmid:6102452 |
McMillin JB et al. | Kinetic properties of carnitine palmitoyltransferase I in cultured neonatal rat cardiac myocytes. | 1994 | Arch. Biochem. Biophys. | pmid:7913595 |
Guzmán M et al. | Effects of proglycosyn (LY177507) on fatty acid metabolism in rat hepatocytes. | 1993 | Arch. Biochem. Biophys. | pmid:8102045 |
Kikuchi S et al. | Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG. | 1992 | Arch. Biochem. Biophys. | pmid:1586161 |
Woldegiorgis G et al. | Restoration of malonyl-CoA sensitivity of soluble rat liver mitochondria carnitine palmitoyltransferase by reconstitution with a partially purified malonyl-CoA binding protein. | 1992 | Arch. Biochem. Biophys. | pmid:1586164 |
Falk KL and Guerra DJ | Coenzyme A biosynthesis in plants: partial purification and characterization of pantothenate kinase from spinach. | 1993 | Arch. Biochem. Biophys. | pmid:8384834 |
Lilly K et al. | The medium-chain carnitine acyltransferase activity associated with rat liver microsomes is malonyl-CoA sensitive. | 1990 | Arch. Biochem. Biophys. | pmid:2353818 |
Kurosaki F | Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot. | 1996 | Arch. Biochem. Biophys. | pmid:8638933 |
Juárez P et al. | A microsomal fatty acid synthetase from the integument of Blattella germanica synthesizes methyl-branched fatty acids, precursors to hydrocarbon and contact sex pheromone. | 1992 | Arch. Biochem. Biophys. | pmid:1536569 |
Horie S et al. | Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of clofibrate and di-(2-ethylhexyl)phthalate on the activity. | 1989 | Arch. Biochem. Biophys. | pmid:2774583 |
Wang D et al. | Acetyl coenzyme A carboxylase activity in neonatal rat cardiac myocytes in culture: citrate dependence and effects of hypoxia. | 1996 | Arch. Biochem. Biophys. | pmid:8561504 |
Hinderer W and Seitz HU | In vitro inhibition of carrot chalcone synthase by 3'-nucleotidase: the role of the 3'-phosphate group of malonyl-coenzyme A in flavonoid biosynthesis. | 1986 | Arch. Biochem. Biophys. | pmid:3008651 |
Zhu H et al. | Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding. | 2003 | Arch. Biochem. Biophys. | pmid:12706342 |
Cook HW | Chain elongation in the formation of polyunsaturated fatty acids by brain: some properties of the microsomal system. | 1982 | Arch. Biochem. Biophys. | pmid:7092216 |
Yoshida S and Takeshita M | Analysis of the condensation step in elongation of very-long-chain saturated and tetraenoic fatty acyl-CoAs in swine cerebral microsomes. | 1987 | Arch. Biochem. Biophys. | pmid:3579295 |
Matern U et al. | Two flavonoid-specific malonyltransferases from cell suspension cultures of Petroselinum hortense: partial purification and some properties of malonyl-coenzyme A: flavone/flavonol-7-O-glycoside malonyltransferase and malonyl-coenzyme A: flavonol-3-O-glucoside malonyltransferase. | 1981 | Arch. Biochem. Biophys. | pmid:7259181 |
Kolattukudy PE et al. | Synthesis of methyl-branched fatty acids from methylmalonyl-CoA by fatty acid synthase from both the liver and the harderian gland of the guinea pig. | 1987 | Arch. Biochem. Biophys. | pmid:3592662 |
Blomquist GJ et al. | Incorporation of [2,3-13C]succinate into methyl-branched alkanes in a termite. | 1980 | Arch. Biochem. Biophys. | pmid:7447468 |
Anderson GJ and Kolattukudy PE | Fatty acid chain elongation by microsomal enzymes from the bovine meibomian gland. | 1985 | Arch. Biochem. Biophys. | pmid:3918501 |
Kurosaki F | Dissociation of dimeric 6-hydroxymellein synthase, a polyketide biosynthetic enzyme in carrot cell extracts, with loss of keto-reducing activity. | 1995 | Arch. Biochem. Biophys. | pmid:7639527 |
Bedord CJ et al. | alpha-linolenic acid biosynthesis in Cyanidium caldarium. | 1978 | Arch. Biochem. Biophys. | pmid:414660 |
Velasco G et al. | Control of hepatic fatty acid oxidation by 5'-AMP-activated protein kinase involves a malonyl-CoA-dependent and a malonyl-CoA-independent mechanism. | 1997 | Arch. Biochem. Biophys. | pmid:9016810 |
Coniglio JG et al. | Effect of hypophysectomy and hormone replacement on fatty elongation in isolated microsomes of rat testes. | 1988 | Arch. Androl. | pmid:3142378 |
Miyahisa I et al. | Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15770480 |
Rodriguez E et al. | Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae. | 2004 | Appl. Microbiol. Biotechnol. | pmid:15179529 |
Rao G et al. | Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23358999 |
Fowler ZL et al. | Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. | 2009 | Appl. Environ. Microbiol. | pmid:19633125 |
RodrÃguez E et al. | Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). | 2001 | Appl. Environ. Microbiol. | pmid:11526020 |
Leonard E et al. | Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. | 2007 | Appl. Environ. Microbiol. | pmid:17468269 |
Chohnan S et al. | Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. | 1997 | Appl. Environ. Microbiol. | pmid:9023936 |
Hunaiti AA and Kolattukudy PE | Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus. | 1984 | Antimicrob. Agents Chemother. | pmid:6143534 |
Slade RF et al. | Characterization and inhibition of fatty acid synthase in pediatric tumor cell lines. | 2003 Mar-Apr | Anticancer Res. | pmid:12820377 |
Wolfgang MJ and Lane MD | Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system. | 2006 | Annu. Rev. Nutr. | pmid:16704352 |
Saggerson D | Malonyl-CoA, a key signaling molecule in mammalian cells. | 2008 | Annu. Rev. Nutr. | pmid:18598135 |
McGarry JD and Foster DW | Regulation of hepatic fatty acid oxidation and ketone body production. | 1980 | Annu. Rev. Biochem. | pmid:6157353 |