Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.
To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Lmfa07050031
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zierz S et al. | Biochemical evidence for heterozygosity in muscular carnitine palmitoyltransferase deficiency. | 1993 | Clin Investig | pmid:8136624 |
Lewandowski ED et al. | Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. | 2013 | Circ. Res. | pmid:22982985 |
Kolwicz SC et al. | Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. | 2012 | Circ. Res. | pmid:22730442 |
Dyck JR et al. | Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. | 2004 | Circ. Res. | pmid:15105298 |
Foster DW and McGarry JD | The regulation of ketogenesis. | 1982 | Ciba Found. Symp. | pmid:6122545 |
Tosin M et al. | Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. | 2009 | Chembiochem | pmid:19507202 |
Musiol EM et al. | The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. | 2013 | Chembiochem | pmid:23828654 |
Awakawa T et al. | 4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. | 2013 | Chembiochem | pmid:23609937 |
Hamed RB et al. | Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles. | 2010 | Chem. Commun. (Camb.) | pmid:20162132 |
Nicholson TP et al. | First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination. | 2003 | Chem. Commun. (Camb.) | pmid:12703773 |
Awakawa T et al. | Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. | 2009 | Chem. Biol. | pmid:19549600 |
Zhou P et al. | Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. | 1999 | Chem. Biol. | pmid:10421763 |
Jensen K et al. | Polyketide proofreading by an acyltransferase-like enzyme. | 2012 | Chem. Biol. | pmid:22444588 |
Kage H et al. | An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. | 2013 | Chem. Biol. | pmid:23790487 |
Ellis JM and Wolfgang MJ | A genetically encoded metabolite sensor for malonyl-CoA. | 2012 | Chem. Biol. | pmid:23102226 |
Hitchman TS et al. | Catalytic self-acylation of type II polyketide synthase acyl carrier proteins. | 1998 | Chem. Biol. | pmid:9479478 |
Zhang S and Kim KH | Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. | 1998 | Cell. Signal. | pmid:9502115 |
Dean JT et al. | Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. | 2009 | Cell Metab. | pmid:19490907 |
Kelley DE | Pulling in more fat. | 2005 | Cell Metab. | pmid:16271525 |
Neschen S et al. | Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. | 2005 | Cell Metab. | pmid:16054099 |
López M et al. | Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. | 2008 | Cell Metab. | pmid:18460330 |
Zammit VA and Arduini A | The AMPK-malonyl-CoA-CPT1 axis in the control of hypothalamic neuronal function. | 2008 | Cell Metab. | pmid:18762014 |
Giordano A et al. | tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. | 2005 | Cell Death Differ. | pmid:15846373 |
Mercier R et al. | Excess membrane synthesis drives a primitive mode of cell proliferation. | 2013 | Cell | pmid:23452849 |
Unger RH | The hyperleptinemia of obesity-regulator of caloric surpluses. | 2004 | Cell | pmid:15084251 |
Kudej RK et al. | Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. | 2011 | Cardiovasc. Res. | pmid:21835931 |
Folmes CD and Lopaschuk GD | Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. | 2007 | Cardiovasc. Res. | pmid:17126822 |
Ussher JR and Lopaschuk GD | The malonyl CoA axis as a potential target for treating ischaemic heart disease. | 2008 | Cardiovasc. Res. | pmid:18499682 |
Ussher JR et al. | Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. | 2012 | Cardiovasc. Res. | pmid:22436846 |
Zhabyeyev P et al. | Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. | 2013 | Cardiovasc. Res. | pmid:23257023 |
Hall JL et al. | Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels. | 1996 | Cardiovasc. Res. | pmid:8944819 |
Wakil SJ et al. | The fatty acid synthetase-structure-function relationship and mechanism of palmitate synthesis. | 1981 Jul-Sep | Cardiovasc Res Cent Bull | pmid:7340934 |
Maurer I and Zierz S | Carnitine palmitoyltransferase in patients with cardiac ischemia due to atherosclerotic coronary artery disease and in patients with idiopathic dilated cardiomyopathy. | 1997 May-Jun | Cardiology | pmid:9129847 |
Li JN et al. | Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. | 2001 | Cancer Res. | pmid:11245456 |
Brusselmans K et al. | RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. | 2005 | Cancer Res. | pmid:16061653 |
Pizer ES et al. | Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. | 2000 | Cancer Res. | pmid:10667561 |
Lopaschuk GD and Gamble J | The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart. | 1994 | Can. J. Physiol. Pharmacol. | pmid:7882173 |
Onay-Besikci A and Sambandam N | Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply. | 2006 | Can. J. Physiol. Pharmacol. | pmid:17218986 |
Akamatsu T et al. | Genetic mapping of bfmA mutation causing fatty acid deficiency in Bacillus subtilis. | 1993 | Can. J. Microbiol. | pmid:8358672 |
Lam KS et al. | In vitro stabilization of 6-methylsalicylic acid synthetase from Penicillium urticae. | 1988 | Can. J. Microbiol. | pmid:3288315 |
Dekleva ML and Strohl WR | Biosynthesis of epsilon-rhodomycinone from glucose by Streptomyces C5 and comparison with intermediary metabolism of other polyketide-producing streptomycetes. | 1988 | Can. J. Microbiol. | pmid:3208200 |
Kaneda T et al. | Fatty acid composition and primer specificity of de novo fatty acid synthetase in Bacillus globispores, Bacillus insolitus, and Bacillus psychrophilus. | 1983 | Can. J. Microbiol. | pmid:6673817 |
Salles J et al. | Fatty acid synthase expression during peripheral nervous system myelination. | 2002 | Brain Res. Mol. Brain Res. | pmid:12007831 |
Sorensen A et al. | Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain. | 2002 | Brain Res. Gene Expr. Patterns | pmid:12638127 |
Gnoni GV et al. | [Effect of nutritional changes on fatty acid synthesis in rat liver microsomes. Role of cyclic AMP]. | 1978 | Boll. Soc. Ital. Biol. Sper. | pmid:219874 |
Zhang X et al. | Improving fatty acid production in Escherichia coli through the overexpression of malonyl coA-acyl carrier protein transacylase. | 2012 Jan-Feb | Biotechnol. Prog. | pmid:22038854 |
Maharjan S et al. | Metabolic engineering of Streptomyces venezuelae for malonyl-CoA biosynthesis to enhance heterologous production of polyketides. | 2010 | Biotechnol. Lett. | pmid:19838628 |
Sugden MC et al. | Lipogenesis in response to an oral glucose load in fed and starved rats. | 1981 | Biosci. Rep. | pmid:7295901 |
Hayashi O and Satoh K | Differences in concentrations of acetyl-CoA and malonyl-CoA in shoots and roots of Zea mays. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18323644 |
Kajikawa M et al. | Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12723610 |