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AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment. |
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Am. J. Physiol. Endocrinol. Metab. |
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Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition. |
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Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases. |
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Biochemistry |
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Identification by mutagenesis of conserved arginine and glutamate residues in the C-terminal domain of rat liver carnitine palmitoyltransferase I that are important for catalytic activity and malonyl-CoA sensitivity. |
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The initiating steps of a type II fatty acid synthase in Plasmodium falciparum are catalyzed by pfACP, pfMCAT, and pfKASIII. |
2003 |
Biochemistry |
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Leucine-764 near the extreme C-terminal end of carnitine palmitoyltransferase I is important for activity. |
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Biochem. Biophys. Res. Commun. |
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Proposed mechanism and functional amino acid residues of malonyl-CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase from flowers of Salvia splendens, a member of the versatile plant acyltransferase family. |
2003 |
Biochemistry |
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Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation. |
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Eur. J. Biochem. |
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2003 |
Proc. Natl. Acad. Sci. U.S.A. |
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Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain. |
2002 |
Brain Res. Gene Expr. Patterns |
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Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis. |
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Am. J. Physiol. Endocrinol. Metab. |
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First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination. |
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Chem. Commun. (Camb.) |
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Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding. |
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Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L. |
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Biosci. Biotechnol. Biochem. |
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Dev. Cell |
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Cloning and tissue distribution of a carnitine palmitoyltransferase I gene in rainbow trout (Oncorhynchus mykiss). |
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Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
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Characterization and inhibition of fatty acid synthase in pediatric tumor cell lines. |
2003 Mar-Apr |
Anticancer Res. |
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A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD). |
2003 |
Anal. Biochem. |
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Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. |
2003 |
J. Biol. Chem. |
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Utilization of long-chain fatty acids in human skeletal muscle during exercise. |
2003 |
Acta Physiol. Scand. |
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AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise. |
2003 |
Acta Physiol. Scand. |
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A template search reveals mechanistic similarities and differences in beta-ketoacyl synthases (KAS) and related enzymes. |
2003 |
Proteins |
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Cloning, expression, characterization, and interaction of two components of a human mitochondrial fatty acid synthase. Malonyltransferase and acyl carrier protein. |
2003 |
J. Biol. Chem. |
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Regulation of CPT I activity in intermyofibrillar and subsarcolemmal mitochondria from human and rat skeletal muscle. |
2004 |
Am. J. Physiol. Endocrinol. Metab. |
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Fatty acid biosynthesis in mitochondria of grasses: malonyl-coenzyme A is generated by a mitochondrial-localized acetyl-coenzyme A carboxylase. |
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Plant Physiol. |
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