Lmfa07050031

Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.

Cross Reference

Introduction

To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lmfa07050031

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Body Weight D001835 333 associated lipids
Heart Failure D006333 36 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Hypothyroidism D007037 32 associated lipids
Per page 10 20 50 | Total 27

PubChem Associated disorders and diseases

What pathways are associated with Lmfa07050031

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

What functions are associated with Lmfa07050031?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lmfa07050031?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Lmfa07050031?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lmfa07050031

Download all related citations
Per page 10 20 50 100 | Total 787
Authors Title Published Journal PubMed Link
Roche E et al. Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression. 1998 Diabetes pmid:9648832
Foster DW Banting lecture 1984. From glycogen to ketones--and back. 1984 Diabetes pmid:6094292
Ido Y et al. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. 2002 Diabetes pmid:11756336
Prentki M and Corkey BE Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? 1996 Diabetes pmid:8593930
Roduit R et al. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. 2004 Diabetes pmid:15047616
Brun T et al. Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling. 1996 Diabetes pmid:8549864
Matschinsky FM Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. 1996 Diabetes pmid:8549869
Prentki M et al. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. 2002 Diabetes pmid:12475783
Bandyopadhyay GK et al. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. 2006 Diabetes pmid:16873691
López M et al. Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA. 2006 Diabetes pmid:16644689
McGarry JD and Foster DW Effects of exogenous fatty acid concentration on glucagon-induced changes in hepatic fatty acid metabolism. 1980 Diabetes pmid:7380110
BÃ¥venholm PN et al. Fatty acid oxidation and the regulation of malonyl-CoA in human muscle. 2000 Diabetes pmid:10909961
Dean D et al. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. 2000 Diabetes pmid:10923628
Oakes ND et al. Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA. 1997 Diabetes pmid:9392490
Shafrir E et al. Regulation of muscle malonyl-CoA levels in the nutritionally insulin-resistant desert gerbil, Psammomys obesus. 2002 May-Jun Diabetes Metab. Res. Rev. pmid:12112940
Prentki M et al. Signal transduction mechanisms in nutrient-induced insulin secretion. 1997 Diabetologia pmid:9248699
Yu X et al. Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. 2004 Diabetologia pmid:15578153
Bell JA et al. Dysregulation of muscle fatty acid metabolism in type 2 diabetes is independent of malonyl-CoA. 2006 Diabetologia pmid:16868746
Glund S et al. Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db mice. 2012 Diabetologia pmid:22532389
Geisler JG Targeting energy expenditure via fuel switching and beyond. 2011 Diabetologia pmid:20953861
Coletta DK et al. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. 2009 Diabetologia pmid:19169664
Similä S et al. [Methylmalonic aciduria]. 1982 Duodecim pmid:7140596
Schujman GE et al. Structural basis of lipid biosynthesis regulation in Gram-positive bacteria. 2006 EMBO J. pmid:16932747
Guzmán-Ruiz R et al. Sensitivity of cardiac carnitine palmitoyltransferase to malonyl-CoA is regulated by leptin: similarities with a model of endogenous hyperleptinemia. 2010 Endocrinology pmid:20056820
Keung W et al. Chronic central leptin decreases food intake and improves glucose tolerance in diet-induced obese mice independent of hypothalamic malonyl CoA levels and skeletal muscle insulin sensitivity. 2011 Endocrinology pmid:21914780
Ruderman NB et al. Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity. 2003 Endocrinology pmid:14500570
Kreuzaler F et al. Flavanone synthase from Petroselinum hortense. Molecular weight, subunit composition, size of messenger RNA, and absence of pantetheinyl residue. 1979 Eur. J. Biochem. pmid:114396
Inui H et al. Fatty acid synthesis in mitochondria of Euglena gracilis. 1984 Eur. J. Biochem. pmid:6146525
Morita H et al. Novel polyketides synthesized with a higher plant stilbene synthase. 2001 Eur. J. Biochem. pmid:11432743
Ghanevati M and Jaworski JG Engineering and mechanistic studies of the Arabidopsis FAE1 beta-ketoacyl-CoA synthase, FAE1 KCS. 2002 Eur. J. Biochem. pmid:12135493
Wölfle K et al. On the mechanism of action of methylmalonyl-CoA mutase. Change of the steric course on isotope substitution. 1986 Eur. J. Biochem. pmid:2870921
Katiyar SS et al. Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A. 1983 Eur. J. Biochem. pmid:6825687
Hügler M et al. Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation. 2003 Eur. J. Biochem. pmid:12581213
McCarthy AD and Hardie DG The multifunctional polypeptide chains of rabbit-mammary fatty-acid synthase. Stoichiometry of active sites and active-site mapping using limited proteolysis. 1983 Eur. J. Biochem. pmid:6549986
Kresze GB et al. Reaction of yeast fatty acid synthetase with iodoacetamide. 3. Malonyl-coenzyme A decarboxylase as product of the reaction of fatty acid synthetase with iodoacetamide. 1977 Eur. J. Biochem. pmid:334544
Schönekess BO et al. Propionyl L-carnitine improvement of hypertrophied rat heart function is associated with an increase in cardiac efficiency. 1995 Eur. J. Pharmacol. pmid:8605952
Trevisan CP et al. Malonyl-CoA abnormal inhibition of residual enzyme activity in carnitine palmitoyltransferase deficiency. 1986 Eur. Neurol. pmid:3720808
Winder WW Malonyl-CoA--regulator of fatty acid oxidation in muscle during exercise. 1998 Exerc Sport Sci Rev pmid:9696987
Brady PS et al. Regulation of the long-chain carnitine acyltransferases. 1993 FASEB J. pmid:8370473
Jenei ZA et al. Packing of transmembrane domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and malonyl-CoA sensitivity of the mitochondrial outer membrane protein. 2011 FASEB J. pmid:21917985
Mingrone G et al. Leptin pulsatility in formerly obese women. 2005 FASEB J. pmid:15955844
Lelliott CJ et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. 2005 FASEB J. pmid:15985534
Lindén D et al. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. 2006 FASEB J. pmid:16507761
Relat J et al. A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme. 2009 FEBS J. pmid:19049515
Springob K et al. A polyketide synthase of Plumbago indica that catalyzes the formation of hexaketide pyrones. 2007 FEBS J. pmid:17229146
Wolfgang MJ and Lane MD Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity. 2011 FEBS J. pmid:21199367
Ghadiminejad I and Saggerson ED Carnitine palmitoyltransferase (CPT2) from liver mitochondrial inner membrane becomes inhibitable by malonyl-CoA if reconstituted with outer membrane malonyl-CoA binding protein. 1990 FEBS Lett. pmid:2401367
Kurosaki F Transacylase-like structure and its role in substrate channeling of 6-hydroxymellein synthase, a multifunctional polyketide biosynthetic enzyme in carrot cell extracts. 1996 FEBS Lett. pmid:8566239
Saggerson ED and Carpenter CA Malonyl CoA inhibition of carnitine acyltransferase activities: effects of thiol-group reagents. 1982 FEBS Lett. pmid:7067817
Naganuma T et al. Biochemical characterization of the very long-chain fatty acid elongase ELOVL7. 2011 FEBS Lett. pmid:21959040