| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Ketosis | D007662 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
Lmfa07050031
Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.
Cross Reference
Introduction
To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lmfa07050031
PubChem Associated disorders and diseases
What pathways are associated with Lmfa07050031
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
What functions are associated with Lmfa07050031?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Lmfa07050031?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lmfa07050031
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xu P et al. | Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli. | 2014 | ACS Chem. Biol. | pmid:24191643 |
| Cardella F | Insulin therapy during diabetic ketoacidosis in children. | 2005 | Acta Biomed | pmid:16915797 |
| Wang YF et al. | Crystallization and preliminary X-ray analysis of the 12S central subunit of transcarboxylase from Propionibacterium shermanii. | 2001 | Acta Crystallogr. D Biol. Crystallogr. | pmid:11173475 |
| Oefner C et al. | Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography. | 2006 | Acta Crystallogr. D Biol. Crystallogr. | pmid:16699188 |
| Ghadbane H et al. | Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). | 2007 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:17909282 |
| Kiens B and Roepstorff C | Utilization of long-chain fatty acids in human skeletal muscle during exercise. | 2003 | Acta Physiol. Scand. | pmid:12864744 |
| Ruderman NB et al. | AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise. | 2003 | Acta Physiol. Scand. | pmid:12864749 |
| Zammit VA et al. | Regulation of mitochondrial outer-membrane carnitine palmitoyltransferase (CPT I): role of membrane-topology. | 1997 | Adv. Enzyme Regul. | pmid:9381976 |
| Saggerson D et al. | Regulation of mitochondrial carnitine palmitoyl transferases from liver and extrahepatic tissues. | 1992 | Adv. Enzyme Regul. | pmid:1496923 |
| Mead JF et al. | Transformations of the polyunsaturated fatty acids in the brain. | 1977 | Adv. Exp. Med. Biol. | pmid:920466 |
| Lopaschuk GD | Malonyl CoA control of fatty acid oxidation in the diabetic rat heart. | 2001 | Adv. Exp. Med. Biol. | pmid:11900364 |
| Hertel K et al. | Kinetic investigation of carnitine palmitoyltransferases in homogenates of human skeletal muscle using L-amino-carnitine and malonyl-CoA. | 1999 | Adv. Exp. Med. Biol. | pmid:10709631 |
| Ruderman NB et al. | Malonyl CoA as a metabolic switch and a regulator of insulin sensitivity. | 1998 | Adv. Exp. Med. Biol. | pmid:9781332 |
| Kikuchi S and Kolattukudy PE | Immobilization of fatty acid synthetase from Mycobacterium smegmatis by radiation-induced polymerization. | 1990 | Agric. Biol. Chem. | pmid:1368562 |
| Guzmán M and Castro J | Alterations in the regulatory properties of hepatic fatty acid oxidation and carnitine palmitoyltransferase I activity after ethanol feeding and withdrawal. | 1990 | Alcohol. Clin. Exp. Res. | pmid:2378434 |
| Maurer I et al. | Carnitine acyltransferases are not changed in Alzheimer disease. | 1998 | Alzheimer Dis Assoc Disord | pmid:9651134 |
| McGarry JD | Glucose-fatty acid interactions in health and disease. | 1998 | Am. J. Clin. Nutr. | pmid:9497160 |
| Kantor PF et al. | Fatty acid oxidation in the reperfused ischemic heart. | 1999 | Am. J. Med. Sci. | pmid:10408755 |
| Saha AK et al. | Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. | 1999 | Am. J. Physiol. | pmid:10362615 |
| Takeyama N et al. | Altered hepatic fatty acid metabolism in endotoxicosis: effect of L-carnitine on survival. | 1989 | Am. J. Physiol. | pmid:2521428 |
| Odland LM et al. | Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans. | 1998 | Am. J. Physiol. | pmid:9611159 |
| Goodwin GW and Taegtmeyer H | Regulation of fatty acid oxidation of the heart by MCD and ACC during contractile stimulation. | 1999 | Am. J. Physiol. | pmid:10516138 |
| Ruderman NB et al. | Malonyl-CoA, fuel sensing, and insulin resistance. | 1999 | Am. J. Physiol. | pmid:9886945 |
| Winder WW et al. | Time course of exercise-induced decline in malonyl-CoA in different muscle types. | 1990 | Am. J. Physiol. | pmid:2166437 |
| Rodnick KJ and Sidell BD | Cold acclimation increases carnitine palmitoyltransferase I activity in oxidative muscle of striped bass. | 1994 | Am. J. Physiol. | pmid:8141397 |
| Saha AK et al. | A malonyl-CoA fuel-sensing mechanism in muscle: effects of insulin, glucose, and denervation. | 1995 | Am. J. Physiol. | pmid:7653546 |
| Odland LM et al. | Human skeletal muscle malonyl-CoA at rest and during prolonged submaximal exercise. | 1996 | Am. J. Physiol. | pmid:8638703 |
| Winder WW and Hardie DG | Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. | 1996 | Am. J. Physiol. | pmid:8779952 |
| Winder WW et al. | Divergence of muscle and liver fructose 2,6-diphosphate in fasted exercising rats. | 1991 | Am. J. Physiol. | pmid:2035632 |
| Saha AK et al. | Lipid abnormalities in tissues of the KKAy mouse: effects of pioglitazone on malonyl-CoA and diacylglycerol. | 1994 | Am. J. Physiol. | pmid:8048519 |
| Laybutt DR et al. | Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat. | 1999 | Am. J. Physiol. | pmid:10600797 |
| Merrill GF et al. | AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. | 1997 | Am. J. Physiol. | pmid:9435525 |
| Hutber CA et al. | Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase. | 1997 | Am. J. Physiol. | pmid:9124333 |
| Thomson DM et al. | LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17925454 |
| Noland RC et al. | Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17638705 |
| Raney MA et al. | AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15547141 |
| Kim JY et al. | Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11934665 |
| Taylor EB et al. | Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15644453 |
| Beha A et al. | Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16380389 |
| Yee AJ and Turcotte LP | Insulin fails to alter plasma LCFA metabolism in muscle perfused at similar glucose uptake. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:12067845 |
| Kraegen EW et al. | Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16234268 |
| Bezaire V et al. | Regulation of CPT I activity in intermyofibrillar and subsarcolemmal mitochondria from human and rat skeletal muscle. | 2004 | Am. J. Physiol. Endocrinol. Metab. | pmid:12954596 |
| Lehtihet M et al. | Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis. | 2003 | Am. J. Physiol. Endocrinol. Metab. | pmid:12684219 |
| Assifi MM et al. | AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15956049 |
| Collier CA et al. | Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16478780 |
| Kuhl JE et al. | Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16434556 |
| Steinberg GR et al. | AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment. | 2003 | Am. J. Physiol. Endocrinol. Metab. | pmid:12441311 |
| Guo W et al. | Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17148751 |
| Sebastián D et al. | CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17062841 |
| Chien D et al. | Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913024 |
| Starritt EC et al. | Sensitivity of CPT I to malonyl-CoA in trained and untrained human skeletal muscle. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10710500 |
| Roepstorff C et al. | Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15383373 |
| Miura S et al. | Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23695215 |
| Gao S et al. | Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23736540 |
| Frøsig C et al. | Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19190265 |
| Longnus SL et al. | Regulation of myocardial fatty acid oxidation by substrate supply. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557544 |
| Zhou L et al. | Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18083904 |
| Sharma V et al. | Metoprolol improves cardiac function and modulates cardiac metabolism in the streptozotocin-diabetic rat. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18203848 |
| King KL et al. | Regulation of cardiac malonyl-CoA content and fatty acid oxidation during increased cardiac power. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15821035 |
| Onay-Besikci A et al. | Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12388233 |
| Poirier M et al. | Probing the link between citrate and malonyl-CoA in perfused rat hearts. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12234788 |
| Goodwin GW and Taegtmeyer H | Improved energy homeostasis of the heart in the metabolic state of exercise. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11009433 |
| Chandler MP et al. | Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15191896 |
| Morash AJ et al. | Genome duplication events have led to a diversification in the CPT I gene family in fish. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20519364 |
| Thyfault JP et al. | Metabolic profiling of muscle contraction in lean compared with obese rodents. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20504904 |
| Richards JG et al. | Lipid oxidation fuels recovery from exhaustive exercise in white muscle of rainbow trout. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11742827 |
| Murase T et al. | Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. | 2006 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:16410398 |
| Lane RH et al. | Uteroplacental insufficiency alters hepatic fatty acid-metabolizing enzymes in juvenile and adult rats. | 2001 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11124150 |
| Gao S et al. | Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21508288 |
| Koves TR et al. | Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism. | 2005 | Am. J. Physiol., Cell Physiol. | pmid:15647392 |
| Onorato JM et al. | Liquid-liquid extraction coupled with LC/MS/MS for monitoring of malonyl-CoA in rat brain tissue. | 2010 | Anal Bioanal Chem | pmid:20549491 |
| Reszko AE et al. | Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. | 2001 | Anal. Biochem. | pmid:11673897 |
| Wang X et al. | Assay of the activity of malonyl-coenzyme A decarboxylase by gas chromatography-mass spectrometry. | 2007 | Anal. Biochem. | pmid:17316539 |
| Bradbury I and Zammit VA | An improved method for the analysis of data from radiation-inactivation studies. | 1990 | Anal. Biochem. | pmid:2363496 |
| Singh B et al. | Determination of malonyl-coenzyme A in rat heart, kidney, and liver: a comparison between acetyl-coenzyme A and butyryl-coenzyme A as fatty acid synthase primers in the assay procedure. | 1984 | Anal. Biochem. | pmid:6731835 |
| De Spiegeleer B et al. | Direct assay for phosphotransacetylase and acetyl-coenzyme A carboxylase by high-performance liquid chromatography. | 1986 | Anal. Biochem. | pmid:2879484 |
| Molnos J et al. | A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD). | 2003 | Anal. Biochem. | pmid:12842120 |
| Minkler PE et al. | Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry. | 2006 | Anal. Biochem. | pmid:16545769 |
| Minkler PE et al. | Isolation and identification of two isomeric forms of malonyl-coenzyme A in commercial malonyl-coenzyme A. | 2004 | Anal. Biochem. | pmid:15113698 |
| Alves J et al. | Cloning, expression, and enzymatic activity of Acinetobacter baumannii and Klebsiella pneumoniae acetyl-coenzyme A carboxylases. | 2011 | Anal. Biochem. | pmid:21704013 |
| Zierz S and Schmitt U | Inhibition of carnitine palmitoyltransferase by malonyl-CoA in human muscle is influenced by anesthesia. | 1989 | Anesthesiology | pmid:2913880 |
| Spiteller D et al. | A method for trapping intermediates of polyketide biosynthesis with a nonhydrolyzable malonyl-coenzyme A analogue. | 2005 | Angew. Chem. Int. Ed. Engl. | pmid:16208728 |
| Ruderman NB et al. | Lipid abnormalities in muscle of insulin-resistant rodents. The malonyl CoA hypothesis. | 1997 | Ann. N. Y. Acad. Sci. | pmid:9329757 |
| Foster DW | The role of the carnitine system in human metabolism. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15590999 |
| Ukropec J et al. | An increase in peroxisomal fatty acid oxidation is not sufficient to prevent tissue lipid accumulation in hHTg rats. | 2002 | Ann. N. Y. Acad. Sci. | pmid:12079837 |
| Wakil SJ | The relationship between structure and function for and the regulation of the enzymes of fatty acid synthesis. | 1986 | Ann. N. Y. Acad. Sci. | pmid:2879500 |
| McGarry JD and Foster DW | Regulation of hepatic fatty acid oxidation and ketone body production. | 1980 | Annu. Rev. Biochem. | pmid:6157353 |
| Dowell P et al. | Monitoring energy balance: metabolites of fatty acid synthesis as hypothalamic sensors. | 2005 | Annu. Rev. Biochem. | pmid:15952896 |
| Wolfgang MJ and Lane MD | Control of energy homeostasis: role of enzymes and intermediates of fatty acid metabolism in the central nervous system. | 2006 | Annu. Rev. Nutr. | pmid:16704352 |
| Saggerson D | Malonyl-CoA, a key signaling molecule in mammalian cells. | 2008 | Annu. Rev. Nutr. | pmid:18598135 |
| Slade RF et al. | Characterization and inhibition of fatty acid synthase in pediatric tumor cell lines. | 2003 Mar-Apr | Anticancer Res. | pmid:12820377 |
| Hunaiti AA and Kolattukudy PE | Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus. | 1984 | Antimicrob. Agents Chemother. | pmid:6143534 |
| Fowler ZL et al. | Increased malonyl coenzyme A biosynthesis by tuning the Escherichia coli metabolic network and its application to flavanone production. | 2009 | Appl. Environ. Microbiol. | pmid:19633125 |
| RodrÃguez E et al. | Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). | 2001 | Appl. Environ. Microbiol. | pmid:11526020 |
| Leonard E et al. | Engineering central metabolic pathways for high-level flavonoid production in Escherichia coli. | 2007 | Appl. Environ. Microbiol. | pmid:17468269 |
| Chohnan S et al. | Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. | 1997 | Appl. Environ. Microbiol. | pmid:9023936 |
| Miyahisa I et al. | Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster. | 2005 | Appl. Microbiol. Biotechnol. | pmid:15770480 |
| Rodriguez E et al. | Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae. | 2004 | Appl. Microbiol. Biotechnol. | pmid:15179529 |
| Rao G et al. | Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23358999 |
| Coniglio JG et al. | Effect of hypophysectomy and hormone replacement on fatty elongation in isolated microsomes of rat testes. | 1988 | Arch. Androl. | pmid:3142378 |