| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Ketosis | D007662 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
Lmfa07050031
Lmfa07050031 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Pigment and Polymerization. The related lipids are Propionate.
Cross Reference
Introduction
To understand associated biological information of Lmfa07050031, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lmfa07050031
PubChem Associated disorders and diseases
What pathways are associated with Lmfa07050031
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
What functions are associated with Lmfa07050031?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Lmfa07050031?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Lmfa07050031?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lmfa07050031
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Guertl B et al. | Metabolic cardiomyopathies. | 2000 | Int J Exp Pathol | pmid:11298185 |
| Jez JM et al. | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. | 2000 | Biochemistry | pmid:10653632 |
| Kennedy JA et al. | Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11117381 |
| Odland LM et al. | Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise. | 2000 | J. Appl. Physiol. | pmid:11090589 |
| Winder WW and Holmes BF | Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated. | 2000 | J. Appl. Physiol. | pmid:11090599 |
| McGarry JD | Malonyl-CoA and satiety? Food for thought. | 2000 | Trends Endocrinol. Metab. | pmid:11091115 |
| Suo Z et al. | Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11106385 |
| Roduit R et al. | Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell. | 2000 | J. Biol. Chem. | pmid:10967113 |
| Jackson VN et al. | Identification of positive and negative determinants of malonyl-CoA sensitivity and carnitine affinity within the amino termini of rat liver- and muscle-type carnitine palmitoyltransferase I. | 2000 | J. Biol. Chem. | pmid:10969089 |
| Goodwin GW and Taegtmeyer H | Improved energy homeostasis of the heart in the metabolic state of exercise. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11009433 |
| Suh DY et al. | Evidence for catalytic cysteine-histidine dyad in chalcone synthase. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10973790 |
| Domergue F et al. | Purification of the acyl-CoA elongase complex from developing rapeseed and characterization of the 3-ketoacyl-CoA synthase and the 3-hydroxyacyl-CoA dehydratase. | 2000 | Lipids | pmid:10907783 |
| BÃ¥venholm PN et al. | Fatty acid oxidation and the regulation of malonyl-CoA in human muscle. | 2000 | Diabetes | pmid:10909961 |
| McGarry JD and Brown NF | Reconstitution of purified, active and malonyl-CoA-sensitive rat liver carnitine palmitoyltransferase I: relationship between membrane environment and malonyl-CoA sensitivity. | 2000 | Biochem. J. | pmid:10861226 |
| Dean D et al. | Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. | 2000 | Diabetes | pmid:10923628 |
| Hamilton C and Saggerson ED | Malonyl-CoA metabolism in cardiac myocytes. | 2000 | Biochem. J. | pmid:10926826 |
| Loftus TM et al. | Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. | 2000 | Science | pmid:10875926 |
| Kerner J and Hoppel C | Fatty acid import into mitochondria. | 2000 | Biochim. Biophys. Acta | pmid:10856709 |
| Chien D et al. | Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913024 |
| Fujii I et al. | Enzymatic synthesis of 1,3,6,8-tetrahydroxynaphthalene solely from malonyl coenzyme A by a fungal iterative type I polyketide synthase PKS1. | 2000 | Biochemistry | pmid:10913297 |
| Gura T | Obesity. Enzyme blocker prompts mice to shed weight. | 2000 | Science | pmid:10917820 |
| Corkey BE et al. | The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction. | 2000 | J. Nutr. | pmid:10721892 |
| Hickson-Bick DL et al. | Palmitate-mediated alterations in the fatty acid metabolism of rat neonatal cardiac myocytes. | 2000 | J. Mol. Cell. Cardiol. | pmid:10731449 |
| Wang YF et al. | Crystallization and preliminary X-ray analysis of the 12S central subunit of transcarboxylase from Propionibacterium shermanii. | 2001 | Acta Crystallogr. D Biol. Crystallogr. | pmid:11173475 |
| Suo Z et al. | Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11134531 |
| Li JN et al. | Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. | 2001 | Cancer Res. | pmid:11245456 |
| Wen J and Kerr RG | Purification and characterization of the fatty acid synthase from Bugula neritina. | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11250539 |
| Reszko AE et al. | Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. | 2001 | Anal. Biochem. | pmid:11673897 |
| RodrÃguez E et al. | Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). | 2001 | Appl. Environ. Microbiol. | pmid:11526020 |
| Rangan VS et al. | Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro. | 2001 | Biochemistry | pmid:11535054 |
| Surendran S et al. | Malonyl CoA decarboxylase deficiency: C to T transition in intron 2 of the MCD gene. | 2001 | J. Neurosci. Res. | pmid:11550227 |
| Morillas M et al. | Structural model of the catalytic core of carnitine palmitoyltransferase I and carnitine octanoyltransferase (COT): mutation of CPT I histidine 473 and alanine 381 and COT alanine 238 impairs the catalytic activity. | 2001 | J. Biol. Chem. | pmid:11553629 |
| Doenst T et al. | Load-induced changes in vivo alter substrate fluxes and insulin responsiveness of rat heart in vitro. | 2001 | Metab. Clin. Exp. | pmid:11555843 |
| Longnus SL et al. | Regulation of myocardial fatty acid oxidation by substrate supply. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11557544 |
| Hamdan M et al. | Inhibition of mitochondrial carnitine palmitoyltransferase-1 by a trimetazidine derivative, S-15176. | 2001 | Pharmacol. Res. | pmid:11516258 |
| Lopaschuk GD | Malonyl CoA control of fatty acid oxidation in the diabetic rat heart. | 2001 | Adv. Exp. Med. Biol. | pmid:11900364 |
| Reeves CD et al. | Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations. | 2001 | Biochemistry | pmid:11747421 |
| Nogalska A and Swierczyński J | [Malonyl-coenzyme A as a signaling molecule in appetite regulation]. | 2001 | Postepy Biochem. | pmid:11757318 |
| McGarry JD | Travels with carnitine palmitoyltransferase I: from liver to germ cell with stops in between. | 2001 | Biochem. Soc. Trans. | pmid:11356162 |
| Eaton S et al. | Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux. | 2001 | Biochem. Soc. Trans. | pmid:11356163 |
| Broadway NM et al. | Microsomal malonyl-CoA-sensitive carnitine acyltransferase. | 2001 | Biochem. Soc. Trans. | pmid:11356165 |
| Zammit VA et al. | Structure-function relationships of the liver and muscle isoforms of carnitine palmitoyltransferase I. | 2001 | Biochem. Soc. Trans. | pmid:11356169 |
| Hegardt FG et al. | Post-transcriptional regulation of rat carnitine octanoyltransferase. | 2001 | Biochem. Soc. Trans. | pmid:11356174 |
| Ruderman N and Flier JS | Cell biology. Chewing the fat--ACC and energy balance. | 2001 | Science | pmid:11286278 |
| Nicot C et al. | Pig liver carnitine palmitoyltransferase I, with low Km for carnitine and high sensitivity to malonyl-CoA inhibition, is a natural chimera of rat liver and muscle enzymes. | 2001 | Biochemistry | pmid:11329295 |
| Brown NF et al. | Molecular characterization of L-CPT I deficiency in six patients: insights into function of the native enzyme. | 2001 | J. Lipid Res. | pmid:11441142 |
| Thupari JN et al. | Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11444828 |
| Eaton S et al. | Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11444876 |
| Morita H et al. | Novel polyketides synthesized with a higher plant stilbene synthase. | 2001 | Eur. J. Biochem. | pmid:11432743 |
| Mulder H et al. | Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells. | 2001 | J. Biol. Chem. | pmid:11113153 |
| Lane RH et al. | Uteroplacental insufficiency alters hepatic fatty acid-metabolizing enzymes in juvenile and adult rats. | 2001 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11124150 |
| Qiu X et al. | Refined structures of beta-ketoacyl-acyl carrier protein synthase III. | 2001 | J. Mol. Biol. | pmid:11243824 |
| Martini WZ et al. | Alteration of hepatic fatty acid metabolism after burn injury in pigs. | 2001 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:11688934 |
| Campbell FM et al. | A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase. | 2002 | J. Biol. Chem. | pmid:11734553 |
| Ido Y et al. | Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. | 2002 | Diabetes | pmid:11756336 |
| Richards JG et al. | Lipid oxidation fuels recovery from exhaustive exercise in white muscle of rainbow trout. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11742827 |
| Nicot C et al. | Pig liver carnitine palmitoyltransferase. Chimera studies show that both the N- and C-terminal regions of the enzyme are important for the unusual high malonyl-CoA sensitivity. | 2002 | J. Biol. Chem. | pmid:11790778 |
| Morillas M et al. | Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domain. | 2002 | J. Biol. Chem. | pmid:11790793 |
| Florova G et al. | Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity. | 2002 | Biochemistry | pmid:12173933 |
| Zheng X et al. | Substrate binding induces a cooperative conformational change in the 12S subunit of transcarboxylase: Raman crystallographic evidence. | 2002 | Biochemistry | pmid:12196011 |
| Witkowski A et al. | Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase. | 2002 | Biochemistry | pmid:12196027 |
| Ghanevati M and Jaworski JG | Engineering and mechanistic studies of the Arabidopsis FAE1 beta-ketoacyl-CoA synthase, FAE1 KCS. | 2002 | Eur. J. Biochem. | pmid:12135493 |
| Hügler M et al. | Malonyl-coenzyme A reductase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO(2) fixation. | 2002 | J. Bacteriol. | pmid:11948153 |
| Kim JY et al. | Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11934665 |
| Yorifuji S | [Mitochondrial carnitine palmitoyltransferase]. | 2002 | Nippon Rinsho | pmid:12014003 |
| Salles J et al. | Fatty acid synthase expression during peripheral nervous system myelination. | 2002 | Brain Res. Mol. Brain Res. | pmid:12007831 |
| Jez JM et al. | Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11959984 |
| Ukropec J et al. | An increase in peroxisomal fatty acid oxidation is not sufficient to prevent tissue lipid accumulation in hHTg rats. | 2002 | Ann. N. Y. Acad. Sci. | pmid:12079837 |
| Yee AJ and Turcotte LP | Insulin fails to alter plasma LCFA metabolism in muscle perfused at similar glucose uptake. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:12067845 |
| Atkinson LL et al. | Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis. | 2002 | J. Biol. Chem. | pmid:12058043 |
| Thupari JN et al. | C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12060712 |
| Richards JG et al. | Substrate utilization during graded aerobic exercise in rainbow trout. | 2002 | J. Exp. Biol. | pmid:12089210 |
| Hirsch J | The search for new ways to treat obesity. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12093927 |
| Verhoeyen ME et al. | Increasing antioxidant levels in tomatoes through modification of the flavonoid biosynthetic pathway. | 2002 | J. Exp. Bot. | pmid:12324533 |
| Pan Y et al. | The extreme C terminus of rat liver carnitine palmitoyltransferase I is not involved in malonyl-CoA sensitivity but in initial protein folding. | 2002 | J. Biol. Chem. | pmid:12351641 |
| Schwarzer D et al. | Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12384573 |
| Laviano A et al. | Energy expenditure and treating obesity. | 2002 | Science | pmid:12387285 |
| Ishihara H and Oka Y | [Mitochondria as the signal generator in the metabolism-secretion coupling in pancreatic beta cells]. | 2002 | Nippon Rinsho | pmid:12430299 |
| Poirier M et al. | Probing the link between citrate and malonyl-CoA in perfused rat hearts. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12234788 |
| Noda M | [Mechanism of glucose-induced insulin secretion]. | 2002 | Nippon Rinsho | pmid:12238044 |
| Dyck JR and Lopaschuk GD | Malonyl CoA control of fatty acid oxidation in the ischemic heart. | 2002 | J. Mol. Cell. Cardiol. | pmid:12392882 |
| Sorensen A et al. | Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain. | 2002 | Brain Res. Gene Expr. Patterns | pmid:12638127 |
| Jensen MD | Fatty acid oxidation in human skeletal muscle. | 2002 | J. Clin. Invest. | pmid:12464664 |
| Rasmussen BB et al. | Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle. | 2002 | J. Clin. Invest. | pmid:12464674 |
| Tomas E et al. | Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12456889 |
| Prentki M et al. | Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. | 2002 | Diabetes | pmid:12475783 |
| Park SH et al. | Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle. | 2002 | J. Appl. Physiol. | pmid:12433937 |
| Takahashi H et al. | Inhibition of very-long-chain fatty acid formation by indanofan, 2-[2-(3-chlorophenyl)oxiran-2-ylmethyl]-2-ethylindan-1,3-dione, and its relatives. | 2002 Jan-Feb | Z. Naturforsch., C, J. Biosci. | pmid:11926546 |
| Shafrir E et al. | Regulation of muscle malonyl-CoA levels in the nutritionally insulin-resistant desert gerbil, Psammomys obesus. | 2002 May-Jun | Diabetes Metab. Res. Rev. | pmid:12112940 |
| Gutières S et al. | Cloning and tissue distribution of a carnitine palmitoyltransferase I gene in rainbow trout (Oncorhynchus mykiss). | 2003 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:12781981 |
| Focke M et al. | Fatty acid biosynthesis in mitochondria of grasses: malonyl-coenzyme A is generated by a mitochondrial-localized acetyl-coenzyme A carboxylase. | 2003 | Plant Physiol. | pmid:12972648 |
| Boren J et al. | The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation. | 2003 | J. Biol. Chem. | pmid:12750369 |
| Nicholson TP et al. | First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination. | 2003 | Chem. Commun. (Camb.) | pmid:12703773 |
| Zhu H et al. | Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding. | 2003 | Arch. Biochem. Biophys. | pmid:12706342 |
| Kajikawa M et al. | Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12723610 |
| Wortman MD et al. | C75 inhibits food intake by increasing CNS glucose metabolism. | 2003 | Nat. Med. | pmid:12724740 |
| Lehtihet M et al. | Glibenclamide inhibits islet carnitine palmitoyltransferase 1 activity, leading to PKC-dependent insulin exocytosis. | 2003 | Am. J. Physiol. Endocrinol. Metab. | pmid:12684219 |
| Molnos J et al. | A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD). | 2003 | Anal. Biochem. | pmid:12842120 |
| Harwood HJ et al. | Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. | 2003 | J. Biol. Chem. | pmid:12842871 |
| Weiss DR and Glickman JF | Characterization of fatty acid synthase activity using scintillation proximity. | 2003 | Assay Drug Dev Technol | pmid:15090142 |