Onay-Besikci A and Sambandam N |
Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply. |
2006 |
Can. J. Physiol. Pharmacol. |
pmid:17218986
|
Li JN et al. |
Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. |
2001 |
Cancer Res. |
pmid:11245456
|
Brusselmans K et al. |
RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. |
2005 |
Cancer Res. |
pmid:16061653
|
Pizer ES et al. |
Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. |
2000 |
Cancer Res. |
pmid:10667561
|
Maurer I and Zierz S |
Carnitine palmitoyltransferase in patients with cardiac ischemia due to atherosclerotic coronary artery disease and in patients with idiopathic dilated cardiomyopathy. |
1997 May-Jun |
Cardiology |
pmid:9129847
|
Wakil SJ et al. |
The fatty acid synthetase-structure-function relationship and mechanism of palmitate synthesis. |
1981 Jul-Sep |
Cardiovasc Res Cent Bull |
pmid:7340934
|
Kudej RK et al. |
Second window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia. |
2011 |
Cardiovasc. Res. |
pmid:21835931
|
Folmes CD and Lopaschuk GD |
Role of malonyl-CoA in heart disease and the hypothalamic control of obesity. |
2007 |
Cardiovasc. Res. |
pmid:17126822
|
Ussher JR and Lopaschuk GD |
The malonyl CoA axis as a potential target for treating ischaemic heart disease. |
2008 |
Cardiovasc. Res. |
pmid:18499682
|
Ussher JR et al. |
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. |
2012 |
Cardiovasc. Res. |
pmid:22436846
|
Zhabyeyev P et al. |
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. |
2013 |
Cardiovasc. Res. |
pmid:23257023
|
Hall JL et al. |
Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels. |
1996 |
Cardiovasc. Res. |
pmid:8944819
|
Mercier R et al. |
Excess membrane synthesis drives a primitive mode of cell proliferation. |
2013 |
Cell |
pmid:23452849
|
Unger RH |
The hyperleptinemia of obesity-regulator of caloric surpluses. |
2004 |
Cell |
pmid:15084251
|
Giordano A et al. |
tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1. |
2005 |
Cell Death Differ. |
pmid:15846373
|
Dean JT et al. |
Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. |
2009 |
Cell Metab. |
pmid:19490907
|
Kelley DE |
Pulling in more fat. |
2005 |
Cell Metab. |
pmid:16271525
|
Neschen S et al. |
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. |
2005 |
Cell Metab. |
pmid:16054099
|
López M et al. |
Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin. |
2008 |
Cell Metab. |
pmid:18460330
|
Zammit VA and Arduini A |
The AMPK-malonyl-CoA-CPT1 axis in the control of hypothalamic neuronal function. |
2008 |
Cell Metab. |
pmid:18762014
|
Zhang S and Kim KH |
Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. |
1998 |
Cell. Signal. |
pmid:9502115
|
Awakawa T et al. |
Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase. |
2009 |
Chem. Biol. |
pmid:19549600
|
Zhou P et al. |
Polyketide synthase acyl carrier protein (ACP) as a substrate and a catalyst for malonyl ACP biosynthesis. |
1999 |
Chem. Biol. |
pmid:10421763
|
Jensen K et al. |
Polyketide proofreading by an acyltransferase-like enzyme. |
2012 |
Chem. Biol. |
pmid:22444588
|
Kage H et al. |
An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. |
2013 |
Chem. Biol. |
pmid:23790487
|
Ellis JM and Wolfgang MJ |
A genetically encoded metabolite sensor for malonyl-CoA. |
2012 |
Chem. Biol. |
pmid:23102226
|
Hitchman TS et al. |
Catalytic self-acylation of type II polyketide synthase acyl carrier proteins. |
1998 |
Chem. Biol. |
pmid:9479478
|
Hamed RB et al. |
Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles. |
2010 |
Chem. Commun. (Camb.) |
pmid:20162132
|
Nicholson TP et al. |
First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination. |
2003 |
Chem. Commun. (Camb.) |
pmid:12703773
|
Tosin M et al. |
Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates. |
2009 |
Chembiochem |
pmid:19507202
|
Musiol EM et al. |
The ATâ‚‚ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. |
2013 |
Chembiochem |
pmid:23828654
|
Awakawa T et al. |
4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum. |
2013 |
Chembiochem |
pmid:23609937
|
Foster DW and McGarry JD |
The regulation of ketogenesis. |
1982 |
Ciba Found. Symp. |
pmid:6122545
|
Lewandowski ED et al. |
Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. |
2013 |
Circ. Res. |
pmid:22982985
|
Kolwicz SC et al. |
Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. |
2012 |
Circ. Res. |
pmid:22730442
|
Dyck JR et al. |
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. |
2004 |
Circ. Res. |
pmid:15105298
|
Zierz S et al. |
Biochemical evidence for heterozygosity in muscular carnitine palmitoyltransferase deficiency. |
1993 |
Clin Investig |
pmid:8136624
|
Zierz S |
Limited trypsin proteolysis renders carnitine palmitoyltransferase insensitive to inhibition by malonyl-CoA in patients with muscle carnitine palmitoyltransferase deficiency. |
1994 |
Clin Investig |
pmid:7711426
|
Escrivá F et al. |
Effect of feeding pattern on the sensitivity of hepatic carnitine palmitoyl-transferase to inhibition by malonyl-CoA in the rat. |
1987 |
Comp Biochem Physiol A Comp Physiol |
pmid:2887369
|
Wen J and Kerr RG |
Purification and characterization of the fatty acid synthase from Bugula neritina. |
2001 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:11250539
|
Gutières S et al. |
Cloning and tissue distribution of a carnitine palmitoyltransferase I gene in rainbow trout (Oncorhynchus mykiss). |
2003 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:12781981
|
LavarÃas S et al. |
Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae). |
2009 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
pmid:19171199
|
Svoronos S and Kumar S |
Decarboxylation of malonyl-CoA by lactating bovine mammary fatty acid synthase. |
1988 |
Comp. Biochem. Physiol., B |
pmid:3396325
|
Lynen F |
New experiments of biotin enzymes. |
1979 |
CRC Crit. Rev. Biochem. |
pmid:41682
|
McGrath RP |
Unusual case of metabolic acidosis. |
1989 |
Crit. Care Med. |
pmid:2909311
|
Harwood HJ |
Acetyl-CoA carboxylase inhibition for the treatment of metabolic syndrome. |
2004 |
Curr Opin Investig Drugs |
pmid:15083594
|
Anderson RC |
Carnitine palmitoyltransferase: a viable target for the treatment of NIDDM? |
1998 |
Curr. Pharm. Des. |
pmid:10197030
|
Schujman GE et al. |
FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis. |
2003 |
Dev. Cell |
pmid:12737802
|
Foster DW |
Banting lecture 1984. From glycogen to ketones--and back. |
1984 |
Diabetes |
pmid:6094292
|
Bandyopadhyay GK et al. |
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. |
2006 |
Diabetes |
pmid:16873691
|