L-octanoylcarnitine

L-octanoylcarnitine is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 311 references associated with L-octanoylcarnitine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for L-octanoylcarnitine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with L-octanoylcarnitine

MeSH term MeSH ID Detail
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Metabolic Diseases D008659 12 associated lipids
Starvation D013217 47 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Insulin Resistance D007333 99 associated lipids
Thinness D013851 11 associated lipids
Heart Failure, Systolic D054143 3 associated lipids
Total 7

PubChem Associated disorders and diseases

All references with L-octanoylcarnitine

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Authors Title Published Journal PubMed Link
pmid:
Mroczkowska JE et al. Blood-brain barrier controls carnitine level in the brain: a study on a model system with RBE4 cells. 2000 Biochem. Biophys. Res. Commun. pmid:10623637
Trumbeckaite S et al. Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. 2001 Eur. J. Biochem. pmid:11231295
Chace DH et al. Errors caused by the use of D,L-octanoylcarnitine for blood-spot calibrators. 2001 Clin. Chem. pmid:11274033
Kameoka J et al. A polymeric microfluidic chip for CE/MS determination of small molecules. 2001 Anal. Chem. pmid:11354473
Carpenter K et al. Evaluation of newborn screening for medium chain acyl-CoA dehydrogenase deficiency in 275 000 babies. 2001 Arch. Dis. Child. Fetal Neonatal Ed. pmid:11517203
Pourfarzam M et al. Neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency. 2001 Lancet pmid:11589939
Toleikis A et al. Relevance of fatty acid oxidation in regulation of the outer mitochondrial membrane permeability for ADP. 2001 FEBS Lett. pmid:11741597
Lehotay DC et al. Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype? 2004 J. Inherit. Metab. Dis. pmid:14970748
Jogl G et al. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. 2005 J. Biol. Chem. pmid:15492013
Farquharson J et al. Direct gas chromatographic assay of urinary medium-chain fatty acylcarnitines by their thermal decomposition. 1992 Clin. Chim. Acta pmid:1576748
Ensenauer R et al. Genotypic differences of MCAD deficiency in the Asian population: novel genotype and clinical symptoms preceding newborn screening notification. 2005 May-Jun Genet. Med. pmid:15915086
de Assis DR et al. Na+, K+ ATPase activity is markedly reduced by cis-4-decenoic acid in synaptic plasma membranes from cerebral cortex of rats. 2006 Exp. Neurol. pmid:16203000
Baumgartner C and Baumgartner D Biomarker discovery, disease classification, and similarity query processing on high-throughput MS/MS data of inborn errors of metabolism. 2006 J Biomol Screen pmid:16314408
Schmidt-Sommerfeld E et al. Urinary medium-chain acylcarnitines in medium-chain acyl-CoA dehydrogenase deficiency, medium-chain triglyceride feeding and valproic acid therapy: sensitivity and specificity of the radioisotopic exchange/high performance liquid chromatography method. 1992 Pediatr. Res. pmid:1635814
Rhead WJ Newborn screening for medium-chain acyl-CoA dehydrogenase deficiency: a global perspective. 2006 Apr-Jun J. Inherit. Metab. Dis. pmid:16763904
Muci MR and Gnoni GV Short-term effects of triiodothyronine on exogenous and de novo synthesized fatty acids in rat hepatocytes. 1991 Biochem. Int. pmid:1804101
Marzo A et al. Protein binding of L-carnitine family components. 1991 Eur J Drug Metab Pharmacokinet pmid:1820909
Hsu HW et al. Spectrum of medium-chain acyl-CoA dehydrogenase deficiency detected by newborn screening. 2008 Pediatrics pmid:18450854
Bhuiyan AK and Pande SV One-step facile synthesis of radioactive acyl-CoA and acylcarnitines using rat liver outer mitochondrial membrane as the enzyme source. 1991 Biochem. Soc. Trans. pmid:1889559
Squire RS Synthesis and purification of radioactive fatty acylcarnitines of high specific activity. 1991 Anal. Biochem. pmid:1952050
Maier EM et al. Dissection of biochemical borderline phenotypes in carriers and genetic variants of medium-chain acyl-CoA dehyrogenase deficiency: implications for newborn screening [corrected]. 2009 Clin. Genet. pmid:19780764
Arnold GL et al. Lack of genotype-phenotype correlations and outcome in MCAD deficiency diagnosed by newborn screening in New York State. 2010 Mol. Genet. Metab. pmid:20036593
Schönfeld P et al. Mitochondrial fatty acid oxidation and oxidative stress: lack of reverse electron transfer-associated production of reactive oxygen species. 2010 Jun-Jul Biochim. Biophys. Acta pmid:20085746
De Jesús VR et al. Comparison of amino acids and acylcarnitines assay methods used in newborn screening assays by tandem mass spectrometry. 2010 Clin. Chim. Acta pmid:20122909
Khalid JM et al. Relationship of octanoylcarnitine concentrations to age at sampling in unaffected newborns screened for medium-chain acyl-CoA dehydrogenase deficiency. 2010 Clin. Chem. pmid:20413428
Kraunsøe R et al. Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity. 2010 J. Physiol. (Lond.) pmid:20421291
Smith EH et al. Allelic diversity in MCAD deficiency: the biochemical classification of 54 variants identified during 5 years of ACADM sequencing. 2010 Mol. Genet. Metab. pmid:20434380
Larsen S et al. Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes. 2011 Diabetologia pmid:21424396
Tonin AM et al. Disruption of redox homeostasis in cerebral cortex of developing rats by acylcarnitines accumulating in medium-chain acyl-CoA dehydrogenase deficiency. 2012 Int. J. Dev. Neurosci. pmid:22472139
Stride N et al. Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction. 2013 Eur. J. Heart Fail. pmid:23115323
Meadows JA and Wargo MJ Characterization of Pseudomonas aeruginosa growth on O-acylcarnitines and identification of a short-chain acylcarnitine hydrolase. 2013 Appl. Environ. Microbiol. pmid:23524670
Alexandre-Gouabau MC et al. Maternal and cord blood LC-HRMS metabolomics reveal alterations in energy and polyamine metabolism, and oxidative stress in very-low birth weight infants. 2013 J. Proteome Res. pmid:23527880
Naccarato A et al. Identification and assay of underivatized urinary acylcarnitines by paper spray tandem mass spectrometry. 2013 Anal Bioanal Chem pmid:23907684
Morand R et al. Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. 2013 Anal Bioanal Chem pmid:23995505
pmid:24845952
pmid:24892382
Donato AJ et al. The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction. 2014 J. Physiol. (Lond.) pmid:25038241
pmid:25454677
Kim M et al. Association between arterial stiffness and serum L-octanoylcarnitine and lactosylceramide in overweight middle-aged subjects: 3-year follow-up study. 2015 PLoS ONE pmid:25781947
pmid:26113437
Horscroft JA et al. Altered Oxygen Utilisation in Rat Left Ventricle and Soleus after 14 Days, but Not 2 Days, of Environmental Hypoxia. 2015 PLoS ONE pmid:26390043
Ojuka E et al. Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:26908505
pmid:26913383
pmid:27055779
Millington DS and Roe CR Medium-chain acyl-CoA dehydrogenase deficiency. 1989 N. Engl. J. Med. pmid:2710197
Brass EP Metabolism of octanoyl- and palmitoylcarnitine by intact rat hepatocytes. 1989 Biochim. Biophys. Acta pmid:2730893
pmid:28190699
Roe CR et al. Post-mortem recognition of inherited metabolic disorders from specific acylcarnitines in tissue in cases of sudden infant death. 1987 Lancet pmid:2881073
DeMaison L et al. Effects of (+)-octanoylcarnitine in intact myocardium. 1988 Jan-Feb Basic Res. Cardiol. pmid:3377743

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