Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Persson HL et al. | Alpha-lipoic acid and alpha-lipoamide prevent oxidant-induced lysosomal rupture and apoptosis. | 2001 | Redox Rep. | pmid:11778851 |
| Owen KQ et al. | Dietary L-carnitine suppresses mitochondrial branched-chain keto acid dehydrogenase activity and enhances protein accretion and carcass characteristics of swine. | 2001 | J. Anim. Sci. | pmid:11811466 |
| Edelmann L et al. | Maple syrup urine disease: identification and carrier-frequency determination of a novel founder mutation in the Ashkenazi Jewish population. | 2001 | Am. J. Hum. Genet. | pmid:11509994 |
| Song JL and Chuang DT | Natural osmolyte trimethylamine N-oxide corrects assembly defects of mutant branched-chain alpha-ketoacid decarboxylase in maple syrup urine disease. | 2001 | J. Biol. Chem. | pmid:11507102 |
| Nishio A et al. | Primary biliary cirrhosis: lessons learned from an organ-specific disease. | 2001 | Clin. Exp. Med. | pmid:11918275 |
| Domingo GJ et al. | Multiple display of peptides and proteins on a macromolecular scaffold derived from a multienzyme complex. | 2001 | J. Mol. Biol. | pmid:11124904 |
| Korotchkina LG et al. | Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal. | 2001 | Free Radic. Biol. Med. | pmid:11316579 |
| Guo Q et al. | Inhibitory effect of alpha-lipoic acid and its positively charged amide analogue on nitric oxide production in RAW 264.7 macrophages. | 2001 | Biochem. Pharmacol. | pmid:11239497 |
| Patel MS and Korotchkina LG | Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases. | 2001 | Exp. Mol. Med. | pmid:11795479 |
| Lutziger I and Oliver DJ | Characterization of two cDNAs encoding mitochondrial lipoamide dehydrogenase from Arabidopsis. | 2001 | Plant Physiol. | pmid:11598235 |