Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen Z et al. | Myocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouse. | 2009 | PLoS ONE | pmid:19440339 |
| Zheng H et al. | Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv. | 2008 | PLoS ONE | pmid:18584054 |
| Günther S et al. | Knockout studies reveal an important role of Plasmodium lipoic acid protein ligase A1 for asexual blood stage parasite survival. | 2009 | PLoS ONE | pmid:19434237 |
| Buchholz K et al. | Depletion of Plasmodium berghei plasmoredoxin reveals a non-essential role for life cycle progression of the malaria parasite. | 2008 | PLoS ONE | pmid:18575607 |
| da Silva Neto JF et al. | Analysis of the organic hydroperoxide response of Chromobacterium violaceum reveals that OhrR is a cys-based redox sensor regulated by thioredoxin. | 2012 | PLoS ONE | pmid:23071722 |
| Pinheiro A et al. | Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues. | 2012 | PLoS ONE | pmid:22675509 |
| Vazquez A et al. | Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation. | 2011 | PLoS ONE | pmid:22073143 |
| Ahidjo BA et al. | VapC toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate VapB antitoxins. | 2011 | PLoS ONE | pmid:21738782 |
| Castro H et al. | Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity. | 2010 | PLoS ONE | pmid:20838623 |
| Burnside K et al. | Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphatase. | 2010 | PLoS ONE | pmid:20552019 |