Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Song JL et al. | Encapsulation of an 86-kDa assembly intermediate inside the cavities of GroEL and its single-ring variant SR1 by GroES. | 2003 | J. Biol. Chem. | pmid:12431983 |
| Wynn RM et al. | Roles of active site and novel K+ ion-binding site residues in human mitochondrial branched-chain alpha-ketoacid decarboxylase/dehydrogenase. | 2001 | J. Biol. Chem. | pmid:11069910 |
| Nemeria N et al. | Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity. | 2005 | J. Biol. Chem. | pmid:15802265 |
| Cabiscol E et al. | Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae. | 2000 | J. Biol. Chem. | pmid:10852912 |
| Wynn RM et al. | Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site. | 2003 | J. Biol. Chem. | pmid:12902323 |
| Kale S et al. | A dynamic loop at the active center of the Escherichia coli pyruvate dehydrogenase complex E1 component modulates substrate utilization and chemical communication with the E2 component. | 2007 | J. Biol. Chem. | pmid:17635929 |
| Gazaryan IG et al. | Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition. | 2007 | J. Biol. Chem. | pmid:17565998 |
| Klyachko NL et al. | pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification. | 2005 | J. Biol. Chem. | pmid:15710613 |
| Argyrou A et al. | Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis. | 2004 | J. Biol. Chem. | pmid:15456792 |
| Li J et al. | The two active sites in human branched-chain alpha-keto acid dehydrogenase operate independently without an obligatory alternating-site mechanism. | 2007 | J. Biol. Chem. | pmid:17329260 |