Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:20029514 | ||||
| pmid:15211516 | ||||
| pmid:20005141 | ||||
| pmid:11527545 | ||||
| pmid:11495999 | ||||
| pmid:22385680 | ||||
| pmid:17033778 | ||||
| pmid:12227466 | ||||
| pmid:11560483 | ||||
| pmid:15384102 | ||||
| pmid: | ||||
| Berthold CL et al. | Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction. | 2007 | Acta Crystallogr. D Biol. Crystallogr. | pmid:18084069 |
| Knorre DG et al. | Chemical and functional aspects of posttranslational modification of proteins. | 2009 | Acta Naturae | pmid:22649613 |
| Fang F and Liu GT | Protective effects of compound FLZ, a novel synthetic analogue of squamosamide, on beta-amyloid-induced rat brain mitochondrial dysfunction in vitro. | 2009 | Acta Pharmacol. Sin. | pmid:19417731 |
| Adams SH | Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. | 2011 | Adv Nutr | pmid:22332087 |
| Edelmann L et al. | Maple syrup urine disease: identification and carrier-frequency determination of a novel founder mutation in the Ashkenazi Jewish population. | 2001 | Am. J. Hum. Genet. | pmid:11509994 |
| Nellis MM and Danner DJ | Gene preference in maple syrup urine disease. | 2001 | Am. J. Hum. Genet. | pmid:11112664 |
| Mayr JA et al. | Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation. | 2011 | Am. J. Hum. Genet. | pmid:22152680 |
| Raj DS et al. | Markers of inflammation, proteolysis, and apoptosis in ESRD. | 2003 | Am. J. Kidney Dis. | pmid:14655193 |
| Sweatt AJ et al. | Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nerves. | 2004 | Am. J. Physiol. Endocrinol. Metab. | pmid:12965870 |