Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nishio A et al. | Primary biliary cirrhosis: lessons learned from an organ-specific disease. | 2001 | Clin. Exp. Med. | pmid:11918275 |
| pmid:11935326 | ||||
| Hengeveld AF and de Kok A | Structural basis of the dysfunctioning of human 2-oxo acid dehydrogenase complexes. | 2002 | Curr. Med. Chem. | pmid:11945122 |
| Cronan JE | Interchangeable enzyme modules. Functional replacement of the essential linker of the biotinylated subunit of acetyl-CoA carboxylase with a linker from the lipoylated subunit of pyruvate dehydrogenase. | 2002 | J. Biol. Chem. | pmid:11956202 |
| Huang S et al. | Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein. | 2002 | Biophys. J. | pmid:11964266 |
| Gao H et al. | The E1beta and E2 subunits of the Bacillus subtilis pyruvate dehydrogenase complex are involved in regulation of sporulation. | 2002 | J. Bacteriol. | pmid:11976308 |
| Omelchenko MV et al. | Recurrent intragenomic recombination leading to sequence homogenization during the evolution of the lipoyl-binding domain. | 2002 | FEMS Microbiol. Lett. | pmid:12007814 |
| Sutton I and Neuberger J | Primary biliary cirrhosis: seeking the silent partner of autoimmunity. | 2002 | Gut | pmid:12010869 |
| Perham RN et al. | Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes. | 2002 | Biochem. Soc. Trans. | pmid:12023822 |
| Morton DH et al. | Diagnosis and treatment of maple syrup disease: a study of 36 patients. | 2002 | Pediatrics | pmid:12042535 |
| pmid:12070266 | ||||
| pmid:12075488 | ||||
| Dursun A et al. | Maple syrup urine disease: mutation analysis in Turkish patients. | 2002 | J. Inherit. Metab. Dis. | pmid:12118532 |
| Porras P et al. | Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12135599 |
| pmid:12163191 | ||||
| Lynch CJ et al. | Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:12217901 |
| Nellis MM et al. | Insulin increases branched-chain alpha-ketoacid dehydrogenase kinase expression in Clone 9 rat cells. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:12217904 |
| Mooney BP et al. | The complex fate of alpha-ketoacids. | 2002 | Annu Rev Plant Biol | pmid:12221980 |
| pmid:12227466 | ||||
| Owen R et al. | Gene therapy for pyruvate dehydrogenase E1alpha deficiency using recombinant adeno-associated virus 2 (rAAV2) vectors. | 2002 | Mol. Ther. | pmid:12231176 |