Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ono K et al. | cDNA cloning of the chicken branched-chain alpha-keto acid dehydrogenase complex. Chicken-specific residues of the acyltransferase affect the overall activity and the interaction with the dehydrogenase. | 2001 | Eur. J. Biochem. | pmid:11168412 |
| pmid:11170645 | ||||
| Obayashi M et al. | Regulation of the activity of branched-chain 2-oxo acid dehydrogenase (BCODH) complex by binding BCODH kinase. | 2001 | FEBS Lett. | pmid:11226417 |
| Xia L et al. | Reduction of ubiquinone by lipoamide dehydrogenase. An antioxidant regenerating pathway. | 2001 | Eur. J. Biochem. | pmid:11231302 |
| Guo Q et al. | Inhibitory effect of alpha-lipoic acid and its positively charged amide analogue on nitric oxide production in RAW 264.7 macrophages. | 2001 | Biochem. Pharmacol. | pmid:11239497 |
| pmid:11243735 | ||||
| Wang X et al. | Acidification and glucocorticoids independently regulate branched-chain alpha-ketoacid dehydrogenase subunit genes. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11287331 |
| Holecek M | Effect of starvation on branched-chain alpha-keto acid dehydrogenase activity in rat heart and skeletal muscle. | 2001 | Physiol Res | pmid:11300223 |
| Korotchkina LG et al. | Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal. | 2001 | Free Radic. Biol. Med. | pmid:11316579 |
| Liu S et al. | Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates. | 2001 | Arch. Biochem. Biophys. | pmid:11368334 |