Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.
To understand associated biological information of lipoamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
lipoamide is suspected in and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with lipoamide
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Hyperglycinemia, Nonketotic | D020158 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bisby RH and Parker AW | Antioxidant reactions of dihydrolipoic acid and lipoamide with triplet duroquinone. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9514912 |
| Sen CK et al. | Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. | 1997 | Free Radic. Biol. Med. | pmid:9098099 |
| Bustamante J et al. | Early redox changes during rat thymocyte apoptosis. | 1997 | Arch. Biochem. Biophys. | pmid:8990276 |
| Pañak KC et al. | Direct determination of glutathione in human blood by micellar electrokinetic chromatography: simultaneous determination of lipoamide and lipoic acid. | 1996 | Electrophoresis | pmid:8957191 |
| Arnér ES et al. | Efficient reduction of lipoamide and lipoic acid by mammalian thioredoxin reductase. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8769129 |
| Mattevi A et al. | Three-dimensional structure of lipoamide dehydrogenase from Pseudomonas fluorescens at 2.8 A resolution. Analysis of redox and thermostability properties. | 1993 | J. Mol. Biol. | pmid:8487301 |
| Thijssen HH et al. | Microsomal lipoamide reductase provides vitamin K epoxide reductase with reducing equivalents. | 1994 | Biochem. J. | pmid:8297331 |
| Sumegi B et al. | Lipoamide influences substrate selection in post-ischaemic perfused rat hearts. | 1994 | Biochem. J. | pmid:7904156 |
| Goldstein BN et al. | Principles of symmetrical organization for the pyruvate dehydrogenase complex. | 1995 | FEBS Lett. | pmid:7589478 |
| Jocelyn PC and Cronshaw AD | The reduction of disulphides by rat liver mitochondria. | 1984 | Biochim. Biophys. Acta | pmid:6421329 |