| MeSH term | MeSH ID | Detail |
|---|---|---|
| Amnesia | D000647 | 12 associated lipids |
| Hypothermia | D007035 | 19 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Edema | D004487 | 152 associated lipids |
Total
5
Elaidamide
Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.
Cross Reference
Introduction
To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Elaidamide?
Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Elaidamide
PubChem Associated disorders and diseases
What pathways are associated with Elaidamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Elaidamide?
There are no associated biomedical information in the current reference collection.
What functions are associated with Elaidamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Elaidamide?
There are no associated biomedical information in the current reference collection.
What genes are associated with Elaidamide?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Elaidamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Elaidamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lichtman AH et al. | Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12065702 |
| Varvel SA et al. | Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16352706 |
| Wu CF et al. | Selective effect of oleamide, an endogenous sleep-inducing lipid amide, on pentylenetetrazole-induced seizures in mice. | 2003 | J. Pharm. Pharmacol. | pmid:12956907 |
| Thomas EA et al. | Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. | 1997 | J. Neurosci. Res. | pmid:9452020 |
| Bannerman P et al. | Early migratory rat neural crest cells express functional gap junctions: evidence that neural crest cell survival requires gap junction function. | 2000 | J. Neurosci. Res. | pmid:10972957 |
| Schweitzer JS et al. | pH Sensitivity of non-synaptic field bursts in the dentate gyrus. | 2000 | J. Neurophysiol. | pmid:10938317 |
| Thomas EA et al. | The endogenous lipid oleamide activates serotonin 5-HT7 neurons in mouse thalamus and hypothalamus. | 1999 | J. Neurochem. | pmid:10349846 |
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| Romero FA et al. | Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. | 2007 | J. Med. Chem. | pmid:17279740 |
| Farrell EK et al. | Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells. | 2012 | J. Lipid Res. | pmid:22095832 |
| Uyama N et al. | Carbenoxolone inhibits DNA synthesis and collagen gene expression in rat hepatic stellate cells in culture. | 2003 | J. Hepatol. | pmid:14568257 |
| Jenkins TC | Fatty acid composition of milk from Holstein cows fed oleamide or canola oil. | 1998 | J. Dairy Sci. | pmid:9565883 |
| Jenkins TC | Lactation performance and fatty acid composition of milk from Holstein cows fed 0 to 5% oleamide. | 1999 | J. Dairy Sci. | pmid:10416167 |
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| Jenkins TC | Feeding oleamide to lactating Jersey cows 1. Effects on lactation performance and milk fatty acid composition. | 2000 | J. Dairy Sci. | pmid:10714869 |
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| Nagasawa K et al. | Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells. | 2006 | J. Cell. Physiol. | pmid:16547974 |
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| Schiller PC et al. | Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro. | 2001 | J. Biol. Chem. | pmid:11278824 |
| Yamada A et al. | Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. | 2016 | J. Biol. Chem. | pmid:26565022 |
| Driscoll WJ et al. | Oleamide synthesizing activity from rat kidney: identification as cytochrome c. | 2007 | J. Biol. Chem. | pmid:17496328 |
| Chen J et al. | Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca/Mn-transport ATPase (SPCA1a). | 2017 | J. Biol. Chem. | pmid:28264934 |
| Togashi K et al. | Dysfunction in gap junction intercellular communication induces aberrant behavior of the inner cell mass and frequent collapses of expanded blastocysts in mouse embryos. | 2015 | J. Assist. Reprod. Genet. | pmid:25917498 |
| Jenkins TC et al. | Site of administration and duration of feeding oleamide to cattle on feed intake and ruminal fatty acid concentrations. | 2000 | J. Anim. Sci. | pmid:11048942 |
| Tubert-Brohman I et al. | Elucidation of hydrolysis mechanisms for fatty acid amide hydrolase and its Lys142Ala variant via QM/MM simulations. | 2006 | J. Am. Chem. Soc. | pmid:17177441 |
| Jenkins TC et al. | Direct methylation procedure for converting fatty amides to fatty acid methyl esters in feed and digesta samples. | 2001 | J. Agric. Food Chem. | pmid:11368568 |
| Cheng MC et al. | Chemical synthesis of 9(Z)-octadecenamide and its hypolipidemic effect: a bioactive agent found in the essential oil of mountain celery seeds. | 2010 | J. Agric. Food Chem. | pmid:20078072 |
| Hei Z et al. | Lipopolysaccharide effects on the proliferation of NRK52E cells via alternations in gap-junction function. | 2012 | J Trauma Acute Care Surg | pmid:22743374 |
| Shim G et al. | Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug. | 2011 | J Control Release | pmid:20971142 |
| Garrido-López A et al. | Comparison of three gas chromatography methods for the determination of slip agents in polyethylene films. | 2007 | J Chromatogr A | pmid:17161408 |
| Garrido-López A et al. | Determination of oleamide and erucamide in polyethylene films by pressurised fluid extraction and gas chromatography. | 2006 | J Chromatogr A | pmid:16716333 |
| Nichols KK et al. | Identification of fatty acids and fatty acid amides in human meibomian gland secretions. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17197513 |
| Lee YJ et al. | Enhanced radiosensitization of p53 mutant cells by oleamide. | 2006 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:16580498 |
| Soria-Gómez E et al. | Oleamide administered into the nucleus accumbens shell regulates feeding behaviour via CB1 and 5-HT2C receptors. | 2010 | Int. J. Neuropsychopharmacol. | pmid:20663269 |
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| Leaphart CL et al. | Interferon-gamma inhibits intestinal restitution by preventing gap junction communication between enterocytes. | 2007 | Gastroenterology | pmid:17570214 |
| Gobbi M et al. | Oleamide-mediated sleep induction does not depend on perturbation of membrane homeoviscosity. | 1999 | FEBS Lett. | pmid:10606738 |
| Huitrón-Reséndiz S et al. | Effect of oleamide on sleep and its relationship to blood pressure, body temperature, and locomotor activity in rats. | 2001 | Exp. Neurol. | pmid:11681856 |
| Rami A et al. | Effective reduction of neuronal death by inhibiting gap junctional intercellular communication in a rodent model of global transient cerebral ischemia. | 2001 | Exp. Neurol. | pmid:11476596 |
| Walentiny DM et al. | The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. | 2011 | Eur. J. Pharmacol. | pmid:21300050 |
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| Hopps JJ et al. | Enhanced vasorelaxant effects of the endocannabinoid-like mediator, oleamide, in hypertension. | 2012 | Eur. J. Pharmacol. | pmid:22465182 |
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| Hill MN and Gorzalka BB | Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test. | 2005 | Eur Neuropsychopharmacol | pmid:15916883 |
| Farrell EK and Merkler DJ | Biosynthesis, degradation and pharmacological importance of the fatty acid amides. | 2008 | Drug Discov. Today | pmid:18598910 |
| Bisogno T et al. | Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. | 2002 | Curr. Pharm. Des. | pmid:11945157 |