MeSH term | MeSH ID | Detail |
---|---|---|
Hypothermia | D007035 | 19 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Edema | D004487 | 152 associated lipids |
Catalepsy | D002375 | 30 associated lipids |
Amnesia | D000647 | 12 associated lipids |
Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.
To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Elaidamide
MeSH term | MeSH ID | Detail |
---|---|---|
Hypothermia | D007035 | 19 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Edema | D004487 | 152 associated lipids |
Catalepsy | D002375 | 30 associated lipids |
Amnesia | D000647 | 12 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
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Fedorova I et al. | Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11561096 |
Lichtman AH et al. | Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12065702 |
Varvel SA et al. | Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16352706 |
Zhang R et al. | One-step formation of straight nanostripes from a mammal lipid-oleamide directly on highly oriented pyrolytic graphite. | 2009 | Langmuir | pmid:19125608 |
Zhang L et al. | Fabrication of microspheres via solvent volatization induced aggregation of self-assembled nanomicellar structures and their use as a pH-dependent drug release system. | 2013 | Langmuir | pmid:23215353 |
Huang JK and Jan CR | Linoleamide, a brain lipid that induces sleep, increases cytosolic Ca2+ levels in MDCK renal tubular cells. | 2001 | Life Sci. | pmid:11212875 |
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Yang J et al. | Connexin 32 and its derived homotypic gap junctional intercellular communication inhibit the migration and invasion of transfected HeLa cells via enhancement of intercellular adhesion. | 2011 Sep-Oct | Mol Med Rep | pmid:21687945 |
SiuYi Leung D et al. | Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. | 2001 | Mol. Cell. Neurosci. | pmid:11461152 |
Alberts GL et al. | Allosteric modulation of the human 5-HT(7A) receptor by lipidic amphipathic compounds. | 2001 | Mol. Pharmacol. | pmid:11723242 |
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Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
Yang JY et al. | The serotonergic system may be involved in the sleep-inducing action of oleamide in rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14615880 |
Adriano E et al. | A novel hypothesis about mechanisms affecting conduction velocity of central myelinated fibers. | 2011 | Neurochem. Res. | pmid:21553257 |
Cheer JF et al. | Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors. | 1999 | Neuropharmacology | pmid:10221757 |
Dougalis A et al. | The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro. | 2004 | Neuropharmacology | pmid:14654098 |
Wise LE et al. | Evaluation of fatty acid amides in the carrageenan-induced paw edema model. | 2008 | Neuropharmacology | pmid:17675189 |
Dougalis A et al. | The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model. | 2004 | Neuropharmacology | pmid:14975678 |
Riquelme MA et al. | The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels. | 2013 | Neuropharmacology | pmid:23583931 |
Mendelson WB and Basile AS | The hypnotic actions of the fatty acid amide, oleamide. | 2001 | Neuropsychopharmacology | pmid:11682271 |
Basile AS et al. | Characterization of the hypnotic properties of oleamide. | 1999 | Neuroreport | pmid:10321465 |
Laposky AD et al. | Deletion of the GABA(A) receptor beta 3 subunit eliminates the hypnotic actions of oleamide in mice. | 2001 | Neuroreport | pmid:11742254 |
Mendelson WB and Basile AS | The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist. | 1999 | Neuroreport | pmid:10574567 |
Murillo-RodrÃguez E et al. | Oleamide modulates memory in rats. | 2001 | Neurosci. Lett. | pmid:11684340 |
Yang JY et al. | Oleamide attenuates apoptotic death in cultured rat cerebellar granule neurons. | 2002 | Neurosci. Lett. | pmid:12133580 |
Egertová M et al. | Fatty acid amide hydrolase expression in rat choroid plexus: possible role in regulation of the sleep-inducing action of oleamide. | 2000 | Neurosci. Lett. | pmid:10713385 |
MartÃnez-González D et al. | Oleamide and anandamide effects on food intake and sexual behavior of rats. | 2004 | Neurosci. Lett. | pmid:15193744 |
Oh YT et al. | Oleamide suppresses lipopolysaccharide-induced expression of iNOS and COX-2 through inhibition of NF-kappaB activation in BV2 murine microglial cells. | 2010 | Neurosci. Lett. | pmid:20298753 |
Kruk-Slomka M et al. | The Influence of the CB1 Receptor Ligands on the Schizophrenia-Like Effects in Mice Induced by MK-801. | 2016 | Neurotox Res | pmid:27577742 |
Krutovskikh VA et al. | Gap junction intercellular communication propagates cell death in cancerous cells. | 2002 | Oncogene | pmid:11960371 |
Yang Y et al. | Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition. | 2014 | Oncol. Rep. | pmid:24317203 |
Yoshitani K et al. | Low concentrations of alendronate increase the local invasive potential of osteoblastic sarcoma cell lines via connexin 43 activation. | 2011 | Pathol. Res. Pract. | pmid:21665377 |
Herrera-SolÃs A et al. | Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20056119 |
Reyes Prieto NM et al. | Oleamide restores sleep in adult rats that were subjected to maternal separation. | 2012 | Pharmacol. Biochem. Behav. | pmid:22975223 |
Munigunti R et al. | Identification of oleamide in Guatteria recurvisepala by LC/MS-based Plasmodium falciparum thioredoxin reductase ligand binding method. | 2011 | Planta Med. | pmid:21567357 |
Au K and Ehrlich HP | Does rat granulation tissue maturation involve gap junction communications? | 2007 | Plast. Reconstr. Surg. | pmid:17572550 |
Ano Y et al. | Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity. | 2015 | PLoS ONE | pmid:25760987 |
Lerner RA | A hypothesis about the endogenous analogue of general anesthesia. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9391028 |
Thomas EA et al. | Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9391162 |
Boger DL et al. | Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9539697 |
Boger DL et al. | Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9560184 |
Hedlund PB et al. | No hypothermic response to serotonin in 5-HT7 receptor knockout mice. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12529502 |
Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
Huidobro-Toro JP and Harris RA | Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine receptors. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8755606 |
Wei XY et al. | Anxiolytic-like effects of oleamide in group-housed and socially isolated mice. | 2007 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:17521793 |
Chaturvedi S et al. | In vivo evidence that N-oleoylglycine acts independently of its conversion to oleamide. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:17085322 |
Langstein J et al. | cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation. | 1996 Jul-Aug | Res. Immunol. | pmid:8903105 |
Cravatt BF et al. | Chemical characterization of a family of brain lipids that induce sleep. | 1995 | Science | pmid:7770779 |
McDonald GR et al. | Bioactive contaminants leach from disposable laboratory plasticware. | 2008 | Science | pmid:18988846 |