MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Catalepsy | D002375 | 30 associated lipids |
Hypothermia | D007035 | 19 associated lipids |
Amnesia | D000647 | 12 associated lipids |
Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.
To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Elaidamide
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Catalepsy | D002375 | 30 associated lipids |
Hypothermia | D007035 | 19 associated lipids |
Amnesia | D000647 | 12 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Méndez-DÃaz M et al. | The endocannabinoid system modulates the valence of the emotion associated to food ingestion. | 2012 | Addict Biol | pmid:21182571 |
Walentiny DM et al. | The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. | 2011 | Eur. J. Pharmacol. | pmid:21300050 |
Liu B et al. | Berberine potentizes apoptosis induced by X-rays irradiation probably through modulation of gap junctions. | 2011 | Chin. Med. J. | pmid:21543001 |
Adriano E et al. | A novel hypothesis about mechanisms affecting conduction velocity of central myelinated fibers. | 2011 | Neurochem. Res. | pmid:21553257 |
Munigunti R et al. | Identification of oleamide in Guatteria recurvisepala by LC/MS-based Plasmodium falciparum thioredoxin reductase ligand binding method. | 2011 | Planta Med. | pmid:21567357 |
Yoshitani K et al. | Low concentrations of alendronate increase the local invasive potential of osteoblastic sarcoma cell lines via connexin 43 activation. | 2011 | Pathol. Res. Pract. | pmid:21665377 |
Desforges B et al. | Gap junctions favor normal rat kidney epithelial cell adaptation to chronic hypertonicity. | 2011 | Am. J. Physiol., Cell Physiol. | pmid:21677260 |
Yang J et al. | Connexin 32 and its derived homotypic gap junctional intercellular communication inhibit the migration and invasion of transfected HeLa cells via enhancement of intercellular adhesion. | 2011 Sep-Oct | Mol Med Rep | pmid:21687945 |
Kim SJ et al. | Therapeutic effects of connexin inhibitors on detrusor overactivity induced by bladder outlet obstruction in rats. | 2011 | Urology | pmid:21820587 |
Farrell EK et al. | Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells. | 2012 | J. Lipid Res. | pmid:22095832 |
Hopps JJ et al. | Enhanced vasorelaxant effects of the endocannabinoid-like mediator, oleamide, in hypertension. | 2012 | Eur. J. Pharmacol. | pmid:22465182 |
Dionisi M et al. | Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro. | 2012 | Lipids Health Dis | pmid:22584002 |
Hei Z et al. | Lipopolysaccharide effects on the proliferation of NRK52E cells via alternations in gap-junction function. | 2012 | J Trauma Acute Care Surg | pmid:22743374 |
Reyes Prieto NM et al. | Oleamide restores sleep in adult rats that were subjected to maternal separation. | 2012 | Pharmacol. Biochem. Behav. | pmid:22975223 |
Zhang L et al. | Fabrication of microspheres via solvent volatization induced aggregation of self-assembled nanomicellar structures and their use as a pH-dependent drug release system. | 2013 | Langmuir | pmid:23215353 |
Riquelme MA et al. | The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels. | 2013 | Neuropharmacology | pmid:23583931 |
Yang Y et al. | Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition. | 2014 | Oncol. Rep. | pmid:24317203 |
pmid:25171777 | ||||
pmid:25641667 | ||||
pmid:25652184 | ||||
pmid:25660201 | ||||
Ano Y et al. | Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity. | 2015 | PLoS ONE | pmid:25760987 |
Togashi K et al. | Dysfunction in gap junction intercellular communication induces aberrant behavior of the inner cell mass and frequent collapses of expanded blastocysts in mouse embryos. | 2015 | J. Assist. Reprod. Genet. | pmid:25917498 |
pmid:26408695 | ||||
pmid:26547872 | ||||
Yamada A et al. | Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. | 2016 | J. Biol. Chem. | pmid:26565022 |
pmid:26711911 | ||||
pmid:27049283 | ||||
pmid:27087645 | ||||
pmid:27152459 | ||||
Kruk-Slomka M et al. | The Influence of the CB1 Receptor Ligands on the Schizophrenia-Like Effects in Mice Induced by MK-801. | 2016 | Neurotox Res | pmid:27577742 |
pmid:27595606 | ||||
Roy A et al. | Identification and characterization of PPARα ligands in the hippocampus. | 2016 | Nat. Chem. Biol. | pmid:27748752 |
Chen J et al. | Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca/Mn-transport ATPase (SPCA1a). | 2017 | J. Biol. Chem. | pmid:28264934 |
pmid:28340410 | ||||
Osmundsen PE | Contact urticaria from nickel and plastic additives (butylhydroxytoluene, oleylamide). | 1980 | Contact Derm. | pmid:7214887 |
Cravatt BF et al. | Chemical characterization of a family of brain lipids that induce sleep. | 1995 | Science | pmid:7770779 |
Huidobro-Toro JP and Harris RA | Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine receptors. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8755606 |
Langstein J et al. | cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation. | 1996 Jul-Aug | Res. Immunol. | pmid:8903105 |
Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
Bisogno T et al. | The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9344854 |
Lerner RA | A hypothesis about the endogenous analogue of general anesthesia. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9391028 |
Thomas EA et al. | Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9391162 |
Guan X et al. | The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. | 1997 | J. Cell Biol. | pmid:9412472 |
Thomas EA et al. | Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. | 1997 | J. Neurosci. Res. | pmid:9452020 |
Boger DL et al. | Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9539697 |
Boger DL et al. | Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9560184 |
Jenkins TC | Fatty acid composition of milk from Holstein cows fed oleamide or canola oil. | 1998 | J. Dairy Sci. | pmid:9565883 |
Yost CS et al. | Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration. | 1998 | Anesth. Analg. | pmid:9620523 |
Bisogno T et al. | Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. | 1998 | Eur. J. Biochem. | pmid:9688276 |
Lees G et al. | Modulation of GABA(A) receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis-9,10-octadecenoamide (cOA). | 1998 | Br. J. Pharmacol. | pmid:9692771 |
Huang GY et al. | Gap junction-mediated cell-cell communication modulates mouse neural crest migration. | 1998 | J. Cell Biol. | pmid:9852163 |
Thomas EA et al. | Oleamide-induced modulation of 5-hydroxytryptamine receptor-mediated signaling. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9928256 |