Elaidamide

Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Elaidamide?

Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Elaidamide

PubChem Associated disorders and diseases

What pathways are associated with Elaidamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What functions are associated with Elaidamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Elaidamide

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Authors Title Published Journal PubMed Link
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Reyes Prieto NM et al. Oleamide restores sleep in adult rats that were subjected to maternal separation. 2012 Pharmacol. Biochem. Behav. pmid:22975223
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Yang J et al. Connexin 32 and its derived homotypic gap junctional intercellular communication inhibit the migration and invasion of transfected HeLa cells via enhancement of intercellular adhesion. 2011 Sep-Oct Mol Med Rep pmid:21687945
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Walentiny DM et al. The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. 2011 Eur. J. Pharmacol. pmid:21300050
Munigunti R et al. Identification of oleamide in Guatteria recurvisepala by LC/MS-based Plasmodium falciparum thioredoxin reductase ligand binding method. 2011 Planta Med. pmid:21567357
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Kim SJ et al. Therapeutic effects of connexin inhibitors on detrusor overactivity induced by bladder outlet obstruction in rats. 2011 Urology pmid:21820587
Oh YT et al. Oleamide suppresses lipopolysaccharide-induced expression of iNOS and COX-2 through inhibition of NF-kappaB activation in BV2 murine microglial cells. 2010 Neurosci. Lett. pmid:20298753
Soria-Gómez E et al. Oleamide administered into the nucleus accumbens shell regulates feeding behaviour via CB1 and 5-HT2C receptors. 2010 Int. J. Neuropsychopharmacol. pmid:20663269
Herrera-Solís A et al. Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. 2010 Pharmacol. Biochem. Behav. pmid:20056119
Cheng MC et al. Chemical synthesis of 9(Z)-octadecenamide and its hypolipidemic effect: a bioactive agent found in the essential oil of mountain celery seeds. 2010 J. Agric. Food Chem. pmid:20078072
Ciovacco WA et al. The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. 2009 Bone pmid:18848655
Sudhahar V et al. Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries. 2009 Eur. J. Pharmacol. pmid:19326479
Lodola A et al. Insights into the mechanism and inhibition of fatty acid amide hydrolase from quantum mechanics/molecular mechanics (QM/MM) modelling. 2009 Biochem. Soc. Trans. pmid:19290863
Zhang R et al. One-step formation of straight nanostripes from a mammal lipid-oleamide directly on highly oriented pyrolytic graphite. 2009 Langmuir pmid:19125608
Mueller GP and Driscoll WJ Biosynthesis of oleamide. 2009 Vitam. Horm. pmid:19647108
Casford MT and Davies PB The structure of oleamide films at the aluminum/oil interface and aluminum/air interface studied by Sum Frequency Generation (SFG) vibrational spectroscopy and Reflection Absorption Infrared Spectroscopy (RAIRS). 2009 ACS Appl Mater Interfaces pmid:20355782
McDonald GR et al. Bioactive contaminants leach from disposable laboratory plasticware. 2008 Science pmid:18988846
Solomonia R et al. Effect of oleamide on pentylenetetrazole-induced seizures in rats. 2008 Bull. Exp. Biol. Med. pmid:19023975
Wise LE et al. Evaluation of fatty acid amides in the carrageenan-induced paw edema model. 2008 Neuropharmacology pmid:17675189
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Wei XY et al. Anxiolytic-like effects of oleamide in group-housed and socially isolated mice. 2007 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:17521793
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Akanmu MA et al. Neuropharmacological effects of oleamide in male and female mice. 2007 Behav. Brain Res. pmid:17588682
Hiley CR and Hoi PM Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? 2007 Cardiovasc Drug Rev pmid:17445087
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Au K and Ehrlich HP Does rat granulation tissue maturation involve gap junction communications? 2007 Plast. Reconstr. Surg. pmid:17572550
Varvel SA et al. Fatty acid amide hydrolase (-/-) mice exhibit an increased sensitivity to the disruptive effects of anandamide or oleamide in a working memory water maze task. 2006 J. Pharmacol. Exp. Ther. pmid:16352706
Grijalvo S et al. Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues. 2006 Chem. Phys. Lipids pmid:16942762
Ehrlich HP et al. Gap junction communications influence upon fibroblast synthesis of Type I collagen and fibronectin. 2006 J. Cell. Biochem. pmid:16475185
Chaturvedi S et al. In vivo evidence that N-oleoylglycine acts independently of its conversion to oleamide. 2006 Prostaglandins Other Lipid Mediat. pmid:17085322
Nagasawa K et al. Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells. 2006 J. Cell. Physiol. pmid:16547974
Hoi PM and Hiley CR Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor. 2006 Br. J. Pharmacol. pmid:16415907
Garrido-López A et al. Determination of oleamide and erucamide in polyethylene films by pressurised fluid extraction and gas chromatography. 2006 J Chromatogr A pmid:16716333
Lee YJ et al. Enhanced radiosensitization of p53 mutant cells by oleamide. 2006 Int. J. Radiat. Oncol. Biol. Phys. pmid:16580498
Tubert-Brohman I et al. Elucidation of hydrolysis mechanisms for fatty acid amide hydrolase and its Lys142Ala variant via QM/MM simulations. 2006 J. Am. Chem. Soc. pmid:17177441
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Hill MN and Gorzalka BB Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test. 2005 Eur Neuropsychopharmacol pmid:15916883
Dougalis A et al. The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro. 2004 Neuropharmacology pmid:14654098
Ito A et al. A derivative of oleamide potently inhibits the spontaneous metastasis of mouse melanoma BL6 cells. 2004 Carcinogenesis pmid:15205356
Martínez-González D et al. Oleamide and anandamide effects on food intake and sexual behavior of rats. 2004 Neurosci. Lett. pmid:15193744
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Leggett JD et al. Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors. 2004 Br. J. Pharmacol. pmid:14707029
Fowler CJ Oleamide: a member of the endocannabinoid family? 2004 Br. J. Pharmacol. pmid:14691053
Lees G and Dougalis A Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. 2004 Brain Res. pmid:14715144
Merkler DJ et al. Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells. 2004 Biochemistry pmid:15449956
Huitron-Resendiz S et al. Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase. 2004 Sleep pmid:15453543
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Wu CF et al. Selective effect of oleamide, an endogenous sleep-inducing lipid amide, on pentylenetetrazole-induced seizures in mice. 2003 J. Pharm. Pharmacol. pmid:12956907
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Heo HJ et al. Effects of oleamide on choline acetyltransferase and cognitive activities. 2003 Biosci. Biotechnol. Biochem. pmid:12843655
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Uyama N et al. Carbenoxolone inhibits DNA synthesis and collagen gene expression in rat hepatic stellate cells in culture. 2003 J. Hepatol. pmid:14568257
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Huang JK and Jan CR Linoleamide, a brain lipid that induces sleep, increases cytosolic Ca2+ levels in MDCK renal tubular cells. 2001 Life Sci. pmid:11212875
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Laposky AD et al. Deletion of the GABA(A) receptor beta 3 subunit eliminates the hypnotic actions of oleamide in mice. 2001 Neuroreport pmid:11742254
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