MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Catalepsy | D002375 | 30 associated lipids |
Hypothermia | D007035 | 19 associated lipids |
Amnesia | D000647 | 12 associated lipids |
Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.
To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Elaidamide
MeSH term | MeSH ID | Detail |
---|---|---|
Edema | D004487 | 152 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Catalepsy | D002375 | 30 associated lipids |
Hypothermia | D007035 | 19 associated lipids |
Amnesia | D000647 | 12 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:28340410 | ||||
pmid:27595606 | ||||
pmid:27152459 | ||||
pmid:27087645 | ||||
pmid:27049283 | ||||
pmid:26711911 | ||||
pmid:26547872 | ||||
pmid:26408695 | ||||
pmid:25660201 | ||||
pmid:25652184 | ||||
pmid:25641667 | ||||
pmid:25171777 | ||||
pmid: | ||||
Casford MT and Davies PB | The structure of oleamide films at the aluminum/oil interface and aluminum/air interface studied by Sum Frequency Generation (SFG) vibrational spectroscopy and Reflection Absorption Infrared Spectroscopy (RAIRS). | 2009 | ACS Appl Mater Interfaces | pmid:20355782 |
Méndez-DÃaz M et al. | The endocannabinoid system modulates the valence of the emotion associated to food ingestion. | 2012 | Addict Biol | pmid:21182571 |
Desforges B et al. | Gap junctions favor normal rat kidney epithelial cell adaptation to chronic hypertonicity. | 2011 | Am. J. Physiol., Cell Physiol. | pmid:21677260 |
Hanus LO et al. | A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids. | 1999 | Anal. Biochem. | pmid:10328778 |
Yost CS et al. | Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration. | 1998 | Anesth. Analg. | pmid:9620523 |
Nicholson RA et al. | Anesthetic-like interaction of the sleep-inducing lipid oleamide with voltage-gated sodium channels in mammalian brain. | 2001 | Anesthesiology | pmid:11135731 |
Thomas EA et al. | Oleamide-induced modulation of 5-hydroxytryptamine receptor-mediated signaling. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9928256 |
Yang JY et al. | Studies on the sedative and hypnotic effects of oleamide in mice. | 1999 | Arzneimittelforschung | pmid:10483511 |
Akanmu MA et al. | Neuropharmacological effects of oleamide in male and female mice. | 2007 | Behav. Brain Res. | pmid:17588682 |
Bisogno T et al. | The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9344854 |
Ransjö M et al. | Expression of connexin 43 mRNA in microisolated murine osteoclasts and regulation of bone resorption in vitro by gap junction inhibitors. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12684060 |
Ritenour-Rodgers KJ et al. | Induction of peptidylglycine alpha-amidating monooxygenase in N(18)TG(2) cells: a model for studying oleamide biosynthesis. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10631094 |
Lo YK et al. | Effect of oleamide on Ca(2+) signaling in human bladder cancer cells. | 2001 | Biochem. Pharmacol. | pmid:11709196 |
Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
Hedlund PB et al. | Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors. | 1999 | Biochem. Pharmacol. | pmid:10571256 |
De Bank PA et al. | A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening. | 2005 | Biochem. Pharmacol. | pmid:15794939 |
Lodola A et al. | Insights into the mechanism and inhibition of fatty acid amide hydrolase from quantum mechanics/molecular mechanics (QM/MM) modelling. | 2009 | Biochem. Soc. Trans. | pmid:19290863 |
Merkler DJ et al. | Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells. | 2004 | Biochemistry | pmid:15449956 |
Boger DL et al. | Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: a probe of structural and conformational features contributing to inhibition. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10021942 |
Boger DL et al. | alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11412972 |
Cherezov V et al. | Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. | 2002 | Biophys. J. | pmid:12496106 |
Heo HJ et al. | Effects of oleamide on choline acetyltransferase and cognitive activities. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12843655 |
Slotema WF et al. | Economically pertinent continuous amide formation by direct lipase-catalyzed amidation with ammonia. | 2003 | Biotechnol. Bioeng. | pmid:12673765 |
Ciovacco WA et al. | The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. | 2009 | Bone | pmid:18848655 |
Laws D et al. | Fatty acid amides are putative endogenous ligands for anaesthetic recognition sites in mammalian CNS. | 2001 | Br J Anaesth | pmid:11517120 |
Lees G et al. | Modulation of GABA(A) receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis-9,10-octadecenoamide (cOA). | 1998 | Br. J. Pharmacol. | pmid:9692771 |
Verdon B et al. | Stereoselective modulatory actions of oleamide on GABA(A) receptors and voltage-gated Na(+) channels in vitro: a putative endogenous ligand for depressant drug sites in CNS. | 2000 | Br. J. Pharmacol. | pmid:10694234 |
Coyne L et al. | The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro. | 2002 | Br. J. Pharmacol. | pmid:11959801 |
Leggett JD et al. | Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors. | 2004 | Br. J. Pharmacol. | pmid:14707029 |
Fowler CJ | Oleamide: a member of the endocannabinoid family? | 2004 | Br. J. Pharmacol. | pmid:14691053 |
Hoi PM and Hiley CR | Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor. | 2006 | Br. J. Pharmacol. | pmid:16415907 |
Foster AM and Sengelaub DR | Bilateral organization of unilaterally generated activity in lumbar spinal motoneurons of the rat. | 2004 | Brain Res. | pmid:15120587 |
Lees G and Dougalis A | Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. | 2004 | Brain Res. | pmid:14715144 |
Solomonia R et al. | Effect of oleamide on pentylenetetrazole-induced seizures in rats. | 2008 | Bull. Exp. Biol. Med. | pmid:19023975 |
Ito A et al. | A derivative of oleamide potently inhibits the spontaneous metastasis of mouse melanoma BL6 cells. | 2004 | Carcinogenesis | pmid:15205356 |
Hiley CR and Hoi PM | Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? | 2007 | Cardiovasc Drug Rev | pmid:17445087 |
Grijalvo S et al. | Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues. | 2006 | Chem. Phys. Lipids | pmid:16942762 |