Elaidamide

Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

Cross Reference

Introduction

To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Elaidamide?

Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Elaidamide

PubChem Associated disorders and diseases

What pathways are associated with Elaidamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What functions are associated with Elaidamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Elaidamide

Download all related citations
Per page 10 20 50 100 | Total 153
Authors Title Published Journal PubMed Link
pmid:
Boger DL et al. Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: a probe of structural and conformational features contributing to inhibition. 1999 Bioorg. Med. Chem. Lett. pmid:10021942
Cheer JF et al. Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors. 1999 Neuropharmacology pmid:10221757
Basile AS et al. Characterization of the hypnotic properties of oleamide. 1999 Neuroreport pmid:10321465
Hanus LO et al. A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids. 1999 Anal. Biochem. pmid:10328778
Thomas EA et al. The endogenous lipid oleamide activates serotonin 5-HT7 neurons in mouse thalamus and hypothalamus. 1999 J. Neurochem. pmid:10349846
Jenkins TC Lactation performance and fatty acid composition of milk from Holstein cows fed 0 to 5% oleamide. 1999 J. Dairy Sci. pmid:10416167
Yang JY et al. Studies on the sedative and hypnotic effects of oleamide in mice. 1999 Arzneimittelforschung pmid:10483511
Hedlund PB et al. Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors. 1999 Biochem. Pharmacol. pmid:10571256
Mendelson WB and Basile AS The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist. 1999 Neuroreport pmid:10574567
Gobbi M et al. Oleamide-mediated sleep induction does not depend on perturbation of membrane homeoviscosity. 1999 FEBS Lett. pmid:10606738
Ritenour-Rodgers KJ et al. Induction of peptidylglycine alpha-amidating monooxygenase in N(18)TG(2) cells: a model for studying oleamide biosynthesis. 2000 Biochem. Biophys. Res. Commun. pmid:10631094
Verdon B et al. Stereoselective modulatory actions of oleamide on GABA(A) receptors and voltage-gated Na(+) channels in vitro: a putative endogenous ligand for depressant drug sites in CNS. 2000 Br. J. Pharmacol. pmid:10694234
Quist AP et al. Physiological role of gap-junctional hemichannels. Extracellular calcium-dependent isosmotic volume regulation. 2000 J. Cell Biol. pmid:10704454
Egertová M et al. Fatty acid amide hydrolase expression in rat choroid plexus: possible role in regulation of the sleep-inducing action of oleamide. 2000 Neurosci. Lett. pmid:10713385
Jenkins TC Feeding oleamide to lactating Jersey cows 1. Effects on lactation performance and milk fatty acid composition. 2000 J. Dairy Sci. pmid:10714869
DeLuca DD and Jenkins TC Feeding oleamide to lactating Jersey cows. 2. Effects on nutrient digestibility, plasma fatty acids, and hormones. 2000 J. Dairy Sci. pmid:10750115
Boger DL et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10805767
Schweitzer JS et al. pH Sensitivity of non-synaptic field bursts in the dentate gyrus. 2000 J. Neurophysiol. pmid:10938317
Bannerman P et al. Early migratory rat neural crest cells express functional gap junctions: evidence that neural crest cell survival requires gap junction function. 2000 J. Neurosci. Res. pmid:10972957
Jenkins TC et al. Site of administration and duration of feeding oleamide to cattle on feed intake and ruminal fatty acid concentrations. 2000 J. Anim. Sci. pmid:11048942
Nicholson RA et al. Anesthetic-like interaction of the sleep-inducing lipid oleamide with voltage-gated sodium channels in mammalian brain. 2001 Anesthesiology pmid:11135731
Huang JK and Jan CR Linoleamide, a brain lipid that induces sleep, increases cytosolic Ca2+ levels in MDCK renal tubular cells. 2001 Life Sci. pmid:11212875
Schiller PC et al. Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro. 2001 J. Biol. Chem. pmid:11278824
Jenkins TC et al. Direct methylation procedure for converting fatty amides to fatty acid methyl esters in feed and digesta samples. 2001 J. Agric. Food Chem. pmid:11368568
Boger DL et al. alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. 2001 Bioorg. Med. Chem. Lett. pmid:11412972
SiuYi Leung D et al. Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons. 2001 Mol. Cell. Neurosci. pmid:11461152
Rami A et al. Effective reduction of neuronal death by inhibiting gap junctional intercellular communication in a rodent model of global transient cerebral ischemia. 2001 Exp. Neurol. pmid:11476596
Laws D et al. Fatty acid amides are putative endogenous ligands for anaesthetic recognition sites in mammalian CNS. 2001 Br J Anaesth pmid:11517120
Fedorova I et al. Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems. 2001 J. Pharmacol. Exp. Ther. pmid:11561096
Fowler CJ et al. Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Biochem. Pharmacol. pmid:11585048
Huitrón-Reséndiz S et al. Effect of oleamide on sleep and its relationship to blood pressure, body temperature, and locomotor activity in rats. 2001 Exp. Neurol. pmid:11681856
Mendelson WB and Basile AS The hypnotic actions of the fatty acid amide, oleamide. 2001 Neuropsychopharmacology pmid:11682271
Murillo-Rodríguez E et al. Oleamide modulates memory in rats. 2001 Neurosci. Lett. pmid:11684340
Lo YK et al. Effect of oleamide on Ca(2+) signaling in human bladder cancer cells. 2001 Biochem. Pharmacol. pmid:11709196
Alberts GL et al. Allosteric modulation of the human 5-HT(7A) receptor by lipidic amphipathic compounds. 2001 Mol. Pharmacol. pmid:11723242
Laposky AD et al. Deletion of the GABA(A) receptor beta 3 subunit eliminates the hypnotic actions of oleamide in mice. 2001 Neuroreport pmid:11742254
Bisogno T et al. Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. 2002 Curr. Pharm. Des. pmid:11945157
Coyne L et al. The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro. 2002 Br. J. Pharmacol. pmid:11959801
Krutovskikh VA et al. Gap junction intercellular communication propagates cell death in cancerous cells. 2002 Oncogene pmid:11960371
Lichtman AH et al. Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. 2002 J. Pharmacol. Exp. Ther. pmid:12065702
Yang JY et al. Oleamide attenuates apoptotic death in cultured rat cerebellar granule neurons. 2002 Neurosci. Lett. pmid:12133580
Coleman AM and Sengelaub DR Patterns of dye coupling in lumbar motor nuclei of the rat. 2002 J. Comp. Neurol. pmid:12410616
Burnside AS and Collas P Induction of Oct-3/4 expression in somatic cells by gap junction-mediated cAMP signaling from blastomeres. 2002 Eur. J. Cell Biol. pmid:12494995
Cherezov V et al. Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase. 2002 Biophys. J. pmid:12496106
Hedlund PB et al. No hypothermic response to serotonin in 5-HT7 receptor knockout mice. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12529502
Slotema WF et al. Economically pertinent continuous amide formation by direct lipase-catalyzed amidation with ammonia. 2003 Biotechnol. Bioeng. pmid:12673765
Ransjö M et al. Expression of connexin 43 mRNA in microisolated murine osteoclasts and regulation of bone resorption in vitro by gap junction inhibitors. 2003 Biochem. Biophys. Res. Commun. pmid:12684060
Heo HJ et al. Effects of oleamide on choline acetyltransferase and cognitive activities. 2003 Biosci. Biotechnol. Biochem. pmid:12843655
Wu CF et al. Selective effect of oleamide, an endogenous sleep-inducing lipid amide, on pentylenetetrazole-induced seizures in mice. 2003 J. Pharm. Pharmacol. pmid:12956907