Elaidamide

Elaidamide is a lipid of Fatty Acyls (FA) class. Elaidamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of Elaidamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Elaidamide?

Elaidamide is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Elaidamide

PubChem Associated disorders and diseases

What pathways are associated with Elaidamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What functions are associated with Elaidamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What genes are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Elaidamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Elaidamide

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Authors Title Published Journal PubMed Link
Chen J et al. Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca/Mn-transport ATPase (SPCA1a). 2017 J. Biol. Chem. pmid:28264934
Roy A et al. Identification and characterization of PPARα ligands in the hippocampus. 2016 Nat. Chem. Biol. pmid:27748752
Kruk-Slomka M et al. The Influence of the CB1 Receptor Ligands on the Schizophrenia-Like Effects in Mice Induced by MK-801. 2016 Neurotox Res pmid:27577742
Yamada A et al. Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. 2016 J. Biol. Chem. pmid:26565022
Togashi K et al. Dysfunction in gap junction intercellular communication induces aberrant behavior of the inner cell mass and frequent collapses of expanded blastocysts in mouse embryos. 2015 J. Assist. Reprod. Genet. pmid:25917498
Ano Y et al. Preventive effects of a fermented dairy product against Alzheimer's disease and identification of a novel oleamide with enhanced microglial phagocytosis and anti-inflammatory activity. 2015 PLoS ONE pmid:25760987
Yang Y et al. Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition. 2014 Oncol. Rep. pmid:24317203
Zhang L et al. Fabrication of microspheres via solvent volatization induced aggregation of self-assembled nanomicellar structures and their use as a pH-dependent drug release system. 2013 Langmuir pmid:23215353
Riquelme MA et al. The ATP required for potentiation of skeletal muscle contraction is released via pannexin hemichannels. 2013 Neuropharmacology pmid:23583931
Méndez-Díaz M et al. The endocannabinoid system modulates the valence of the emotion associated to food ingestion. 2012 Addict Biol pmid:21182571
Farrell EK et al. Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells. 2012 J. Lipid Res. pmid:22095832
Dionisi M et al. Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro. 2012 Lipids Health Dis pmid:22584002
Reyes Prieto NM et al. Oleamide restores sleep in adult rats that were subjected to maternal separation. 2012 Pharmacol. Biochem. Behav. pmid:22975223
Hei Z et al. Lipopolysaccharide effects on the proliferation of NRK52E cells via alternations in gap-junction function. 2012 J Trauma Acute Care Surg pmid:22743374
Hopps JJ et al. Enhanced vasorelaxant effects of the endocannabinoid-like mediator, oleamide, in hypertension. 2012 Eur. J. Pharmacol. pmid:22465182
Yang J et al. Connexin 32 and its derived homotypic gap junctional intercellular communication inhibit the migration and invasion of transfected HeLa cells via enhancement of intercellular adhesion. 2011 Sep-Oct Mol Med Rep pmid:21687945
Desforges B et al. Gap junctions favor normal rat kidney epithelial cell adaptation to chronic hypertonicity. 2011 Am. J. Physiol., Cell Physiol. pmid:21677260
Yoshitani K et al. Low concentrations of alendronate increase the local invasive potential of osteoblastic sarcoma cell lines via connexin 43 activation. 2011 Pathol. Res. Pract. pmid:21665377
Liu B et al. Berberine potentizes apoptosis induced by X-rays irradiation probably through modulation of gap junctions. 2011 Chin. Med. J. pmid:21543001
Shim G et al. Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug. 2011 J Control Release pmid:20971142
Walentiny DM et al. The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. 2011 Eur. J. Pharmacol. pmid:21300050
Munigunti R et al. Identification of oleamide in Guatteria recurvisepala by LC/MS-based Plasmodium falciparum thioredoxin reductase ligand binding method. 2011 Planta Med. pmid:21567357
Adriano E et al. A novel hypothesis about mechanisms affecting conduction velocity of central myelinated fibers. 2011 Neurochem. Res. pmid:21553257
Kim SJ et al. Therapeutic effects of connexin inhibitors on detrusor overactivity induced by bladder outlet obstruction in rats. 2011 Urology pmid:21820587
Oh YT et al. Oleamide suppresses lipopolysaccharide-induced expression of iNOS and COX-2 through inhibition of NF-kappaB activation in BV2 murine microglial cells. 2010 Neurosci. Lett. pmid:20298753
Soria-Gómez E et al. Oleamide administered into the nucleus accumbens shell regulates feeding behaviour via CB1 and 5-HT2C receptors. 2010 Int. J. Neuropsychopharmacol. pmid:20663269
Herrera-Solís A et al. Acute and subchronic administration of anandamide or oleamide increases REM sleep in rats. 2010 Pharmacol. Biochem. Behav. pmid:20056119
Cheng MC et al. Chemical synthesis of 9(Z)-octadecenamide and its hypolipidemic effect: a bioactive agent found in the essential oil of mountain celery seeds. 2010 J. Agric. Food Chem. pmid:20078072
Ciovacco WA et al. The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. 2009 Bone pmid:18848655
Sudhahar V et al. Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries. 2009 Eur. J. Pharmacol. pmid:19326479
Lodola A et al. Insights into the mechanism and inhibition of fatty acid amide hydrolase from quantum mechanics/molecular mechanics (QM/MM) modelling. 2009 Biochem. Soc. Trans. pmid:19290863
Zhang R et al. One-step formation of straight nanostripes from a mammal lipid-oleamide directly on highly oriented pyrolytic graphite. 2009 Langmuir pmid:19125608
Mueller GP and Driscoll WJ Biosynthesis of oleamide. 2009 Vitam. Horm. pmid:19647108
Casford MT and Davies PB The structure of oleamide films at the aluminum/oil interface and aluminum/air interface studied by Sum Frequency Generation (SFG) vibrational spectroscopy and Reflection Absorption Infrared Spectroscopy (RAIRS). 2009 ACS Appl Mater Interfaces pmid:20355782
McDonald GR et al. Bioactive contaminants leach from disposable laboratory plasticware. 2008 Science pmid:18988846
Solomonia R et al. Effect of oleamide on pentylenetetrazole-induced seizures in rats. 2008 Bull. Exp. Biol. Med. pmid:19023975
Wise LE et al. Evaluation of fatty acid amides in the carrageenan-induced paw edema model. 2008 Neuropharmacology pmid:17675189
Farrell EK and Merkler DJ Biosynthesis, degradation and pharmacological importance of the fatty acid amides. 2008 Drug Discov. Today pmid:18598910
Nichols KK et al. Identification of fatty acids and fatty acid amides in human meibomian gland secretions. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17197513
Ohba Y et al. Oleamide derivatives suppress the spontaneous metastasis by inhibiting connexin 26. 2007 Int. J. Cancer pmid:17290388
Romero FA et al. Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17279740
Wei XY et al. Anxiolytic-like effects of oleamide in group-housed and socially isolated mice. 2007 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:17521793
Saito M et al. The functional interrelationship between gap junctions and fenestrae in endothelial cells of the liver organoid. 2007 J. Membr. Biol. pmid:17568973
Leaphart CL et al. Interferon-gamma inhibits intestinal restitution by preventing gap junction communication between enterocytes. 2007 Gastroenterology pmid:17570214
Akanmu MA et al. Neuropharmacological effects of oleamide in male and female mice. 2007 Behav. Brain Res. pmid:17588682
Hiley CR and Hoi PM Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? 2007 Cardiovasc Drug Rev pmid:17445087
Driscoll WJ et al. Oleamide synthesizing activity from rat kidney: identification as cytochrome c. 2007 J. Biol. Chem. pmid:17496328
Garrido-López A et al. Comparison of three gas chromatography methods for the determination of slip agents in polyethylene films. 2007 J Chromatogr A pmid:17161408
Nojima H et al. Oleamide derivatives are prototypical anti-metastasis drugs that act by inhibiting Connexin 26. 2007 Curr Drug Saf pmid:18690969
Au K and Ehrlich HP Does rat granulation tissue maturation involve gap junction communications? 2007 Plast. Reconstr. Surg. pmid:17572550