N-arachidonoyl glycine

N-arachidonoyl glycine is a lipid of Fatty Acyls (FA) class. The involved functions are known as synergism. N-arachidonoyl glycine often locates in Microglial and Nuchal region. The associated genes with N-arachidonoyl glycine are LPAR5 gene and LPAR4 gene.

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Introduction

To understand associated biological information of N-arachidonoyl glycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with N-arachidonoyl glycine?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with N-arachidonoyl glycine

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Edema D004487 152 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with N-arachidonoyl glycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with N-arachidonoyl glycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with N-arachidonoyl glycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with N-arachidonoyl glycine?

There are no associated biomedical information in the current reference collection.

What genes are associated with N-arachidonoyl glycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with N-arachidonoyl glycine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with N-arachidonoyl glycine

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Authors Title Published Journal PubMed Link
Leishman E et al. Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain. 2016 Biochim. Biophys. Acta pmid:26956082
Koltyn KF et al. Mechanisms of exercise-induced hypoalgesia. 2014 J Pain pmid:25261342
Console-Bram L et al. Activation of GPR18 by cannabinoid compounds: a tale of biased agonism. 2014 Br. J. Pharmacol. pmid:24762058
Cazade M et al. Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2. 2014 Mol. Pharmacol. pmid:24214826
Davenport AP et al. International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands. 2013 Pharmacol. Rev. pmid:23686350
Deak AT et al. The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by preventing STIM1-Orai1 interaction. 2013 J. Cell. Sci. pmid:23239024
Lu VB et al. N-Arachidonyl glycine does not activate G protein-coupled receptor 18 signaling via canonical pathways. 2013 Mol. Pharmacol. pmid:23104136
Caldwell MD et al. A GPR18-based signalling system regulates IOP in murine eye. 2013 Br. J. Pharmacol. pmid:23461720
Bondarenko AI et al. N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs. 2013 Br. J. Pharmacol. pmid:23517055
Gustafsson SB et al. Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. 2013 Arch. Toxicol. pmid:23552853