Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

Cross Reference

Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Sudden Infant Death D013398 3 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Hyperthyroidism D006980 12 associated lipids
Refsum Disease D012035 19 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

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Authors Title Published Journal PubMed Link
Tomosaka H et al. Lupeol esters from the twig bark of Japanese pear (Pyrus serotina Rehd.) cv. Shinko. 2001 Biosci. Biotechnol. Biochem. pmid:11440139
Maulik PR and Shipley GG X-ray diffraction and calorimetric study of N-lignoceryl sphingomyelin membranes. 1995 Biophys. J. pmid:8580334
ten Grotenhuis E et al. Phase behavior of stratum corneum lipids in mixed Langmuir-Blodgett monolayers. 1996 Biophys. J. pmid:8874014
Mojumdar EH et al. Localization of cholesterol and fatty acid in a model lipid membrane: a neutron diffraction approach. 2013 Biophys. J. pmid:23972843
Mojumdar EH et al. Skin lipids: localization of ceramide and fatty acid in the unit cell of the long periodicity phase. 2015 Biophys. J. pmid:26039168
Pullmannová P et al. Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. 2017 Biophys. Chem. pmid:28363088
Veerapen N et al. Synthesis and biological activity of alpha-L-fucosyl ceramides, analogues of the potent agonist, alpha-D-galactosyl ceramide KRN7000. 2010 Bioorg. Med. Chem. Lett. pmid:20462758
Wanders RJ et al. Studies on the peroxisomal oxidation of palmitate and lignocerate in rat liver. 1987 Biochim. Biophys. Acta pmid:2952173
Singh I et al. Acyl-CoA ligases from rat brain microsomes: an immunochemical study. 1988 Biochim. Biophys. Acta pmid:2973813
Morrow MR et al. Glycosphingolipid acyl chain order profiles: substituent effects. 1995 Biochim. Biophys. Acta pmid:7756331
Veerkamp JH and van Moerkerk HT Peroxisomal fatty acid oxidation in rat and human tissues. Effect of nutritional state, clofibrate treatment and postnatal development in the rat. 1986 Biochim. Biophys. Acta pmid:3942767
Vargas CR et al. Evidence that oxidative stress is increased in patients with X-linked adrenoleukodystrophy. 2004 Biochim. Biophys. Acta pmid:14732478
Hayashi H and Oohashi M Incorporation of acetyl-CoA generated from peroxisomal beta-oxidation into ethanolamine plasmalogen of rat liver. 1995 Biochim. Biophys. Acta pmid:7857972
Singh I et al. Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. 1993 Biochim. Biophys. Acta pmid:8399326
Gulati S et al. Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. 1993 Biochim. Biophys. Acta pmid:8399363
Oguri M et al. The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes. 2014 Biochim. Biophys. Acta pmid:24565794
DiRusso CC et al. Functional domains of the fatty acid transport proteins: studies using protein chimeras. 2008 Biochim. Biophys. Acta pmid:18258213
Reubsaet FA et al. Immunochemical and biochemical studies of fatty acid oxidation in fibroblasts of Zellweger and X-linked adrenoleukodystrophy patients. 1991 Biochim. Biophys. Acta pmid:2049396
Bentejac M et al. Time-course of utilization of [stearic or lignoceric acid]sphingomyelin from high-density lipoprotein by rat tissues. 1990 Biochim. Biophys. Acta pmid:2317523
Crook SJ et al. Factors affecting surface expression of glycolipids: influence of lipid environment and ceramide composition on antibody recognition of cerebroside sulfate in liposomes. 1986 Biochemistry pmid:3801428
Lu D et al. Effect of glycosphingolipid fatty acid chain length on behavior in unsaturated phosphatidylcholine bilayers: a 2H NMR study. 1993 Biochemistry pmid:8418849
Uda M et al. Glutamate formed from lignoceric acid by rat brain preparation in the presence of pyridine nucleotide and cytosolic factors: a brain-specific oxidation of very long chain fatty acids. 1981 Biochemistry pmid:7225329
Hashimoto F et al. Effect of gemfibrozil on lipid biosynthesis from acetyl-CoA derived from peroxisomal beta-oxidation. 1995 Biochem. Pharmacol. pmid:7763302
Lageweg W and Wanders RJ Studies on the effect of fenoprofen on the activation and oxidation of long chain and very long chain fatty acids in hepatocytes and subcellular fractions from rat liver. 1993 Biochem. Pharmacol. pmid:8347139
Street JM et al. Metabolism of saturated and polyunsaturated very-long-chain fatty acids in fibroblasts from patients with defects in peroxisomal beta-oxidation. 1990 Biochem. J. pmid:2117919
GRAY GM THE ISOLATION AND PARTIAL CHARACTERIZATION OF THE GLYCOLIPIDS OF BP8/C3H ASCITES-SARCOMA CELLS. 1965 Biochem. J. pmid:14342256
Soeda S et al. Immobilization of fatty acyl-CoA synthetase: effect on its stability and substrate specificity. 1986 Biochem. Int. pmid:3964283
Bourre JM et al. Biosynthesis of lignoceric acid from behenyl0COA in mouse brain microsomes. Comparison between normal and Quaking mutant. 1975 Biochem. Biophys. Res. Commun. pmid:236752
Singh I and Kishimoto Y A novel synthesis of ceramide from lignoceric acid and sphingosine by rat brain preparation; the amide formation requires a pyridine nucleotide. 1978 Biochem. Biophys. Res. Commun. pmid:29620
Aoyama T et al. Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system. 1994 Biochem. Biophys. Res. Commun. pmid:8024599
Kawamura N et al. Very long chain fatty acid oxidation in rat liver. 1981 Biochem. Biophys. Res. Commun. pmid:7259776
Steinberg SJ et al. Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism. 1999 Biochem. Biophys. Res. Commun. pmid:10198260
Iida H et al. Alterations in erythrocyte membrane lipids in abetalipoproteinemia: phospholipid and fatty acyl composition. 1984 Biochem Med pmid:6497872
Elewaut D Natural killer T cells and rheumatoid arthritis: friend or foe? 2005 Arthritis Res. Ther. pmid:15743495
Singh H et al. Very long chain fatty acid beta-oxidation by subcellular fractions of normal and Zellweger syndrome skin fibroblasts. 1987 Arch. Biochem. Biophys. pmid:3662528
Bhushan A et al. Characterization of rat brain microsomal acyl-coenzyme A ligases: different enzymes for the synthesis of palmitoyl-coenzyme A and lignoceroyl-coenzyme A. 1986 Arch. Biochem. Biophys. pmid:3963826
Tatsumi K et al. Mechanism and stereospecificity of alpha-hydroxylation of lignoceric acid in rat brain. 1975 Arch. Biochem. Biophys. pmid:1190799
Cassagne C and Lessire R Studies on alkane biosynthesis in epidermis of Allium porrum L. leaves. Direct synthesis of tricosane from lignoceric acid. 1974 Arch. Biochem. Biophys. pmid:4441076
Shimeno H et al. Further characterization of the heat-stable factor in the alpha-hydroxylation and oxidation of lignoceric acid in brain: effect of acidic amino acids and hexose-phosphates on brain fatty acid metabolism. 1983 Arch. Biochem. Biophys. pmid:6859867
Singh H and Poulos A A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. 1986 Arch. Biochem. Biophys. pmid:3767370
Uda M et al. Purification of the heat-stable factor required for alpha-hydroxylation and beta-oxidation of very long chain fatty acids in brain. 1982 Arch. Biochem. Biophys. pmid:7103506
Gulati S et al. Ischemia-reperfusion injury: biochemical alterations in peroxisomes of rat kidney. 1992 Arch. Biochem. Biophys. pmid:1575521
Bohn M et al. Lipid composition and fluidity of plasma membranes isolated from corn (Zea mays L.) roots. 2001 Arch. Biochem. Biophys. pmid:11368181
Singh I et al. Lignoceroyl-CoA ligase activity in rat brain microsomal fraction: topographical localization and effect of detergents and alpha-cyclodextrin. 1985 Arch. Biochem. Biophys. pmid:2578272
Singh H et al. Beta-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts. 1987 Arch. Biochem. Biophys. pmid:2437859
Chavez JA and Summers SA Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. 2003 Arch. Biochem. Biophys. pmid:14592453
Hayashi H and Takahata S Role of peroxisomal fatty acyl-CoA beta-oxidation in phospholipid biosynthesis. 1991 Arch. Biochem. Biophys. pmid:1989516
Lazo O et al. Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. 1989 Arch. Biochem. Biophys. pmid:2705786
Moldes AB et al. Comparison between different hydrolysis processes of vine-trimming waste to obtain hemicellulosic sugars for further lactic acid conversion. 2007 Appl. Biochem. Biotechnol. pmid:18057452
Jantzen E et al. Gas chromatography of mycobacterial fatty acids and alcohols: diagnostic applications. 1989 APMIS pmid:2590535