| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
| Diffuse Cerebral Sclerosis of Schilder | D002549 | 8 associated lipids |
| Abetalipoproteinemia | D000012 | 7 associated lipids |
| Sudden Infant Death | D013398 | 3 associated lipids |
Lignoceric acid
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
Cross Reference
Introduction
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lignoceric acid?
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lignoceric acid
PubChem Associated disorders and diseases
What pathways are associated with Lignoceric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lignoceric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lignoceric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lignoceric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lignoceric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lignoceric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lignoceric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lazo O et al. | Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. | 1989 | Arch. Biochem. Biophys. | pmid:2705786 |
| Bentejac M et al. | Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. | 1989 | J. Neurochem. | pmid:2709013 |
| Morita M et al. | A novel method for determining peroxisomal fatty acid β-oxidation. | 2016 | J. Inherit. Metab. Dis. | pmid:27324171 |
| Singh H et al. | Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. | 1989 | J. Neurochem. | pmid:2809586 |
| Bezine M et al. | Evidence of K homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes. | 2017 | Chem. Phys. Lipids | pmid:28322741 |
| Pullmannová P et al. | Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. | 2017 | Biophys. Chem. | pmid:28363088 |
| Poll-The BT et al. | A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy). | 1988 | Am. J. Hum. Genet. | pmid:2894756 |
| Wanders RJ et al. | Impaired ability of peroxisomes to activate very-long-chain fatty acids in X-linked adrenoleukodystrophy. | 1988 | Lancet | pmid:2899227 |
| Carneheim C et al. | Rare fatty acids in brown fat are substrates for thermogenesis during arousal from hibernation. | 1989 | Am. J. Physiol. | pmid:2912207 |
| Iida N et al. | A sulfated glucosylceramide from rat kidney. | 1989 | J. Biol. Chem. | pmid:2925645 |
| Wanders RJ et al. | Studies on the peroxisomal oxidation of palmitate and lignocerate in rat liver. | 1987 | Biochim. Biophys. Acta | pmid:2952173 |
| Singh I and Kishimoto Y | A novel synthesis of ceramide from lignoceric acid and sphingosine by rat brain preparation; the amide formation requires a pyridine nucleotide. | 1978 | Biochem. Biophys. Res. Commun. | pmid:29620 |
| Singh I et al. | Acyl-CoA ligases from rat brain microsomes: an immunochemical study. | 1988 | Biochim. Biophys. Acta | pmid:2973813 |
| Lazo O et al. | Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3174658 |
| De Lederkremer RM et al. | Lipopeptidophosphoglycan from Trypanosoma cruzi. Amide and ester-linked fatty acids. | 1977 | Eur. J. Biochem. | pmid:323009 |
| Sacktor NC et al. | Effects of subperineurial injections of very-long-chain and medium-chain fatty acids into rat sciatic nerve. | 1986 | Neurochem Pathol | pmid:3561895 |
| Galloway JH et al. | Abnormal myocardial lipid composition in an infant with type II glutaric aciduria. | 1987 | J. Lipid Res. | pmid:3572253 |
| Tanaka K et al. | Electronmicroscopic study on biopsied rectal mucosa in adrenoleukodystrophy. | 1987 | Neurology | pmid:3587618 |
| Singh H et al. | Very long chain fatty acid beta-oxidation by subcellular fractions of normal and Zellweger syndrome skin fibroblasts. | 1987 | Arch. Biochem. Biophys. | pmid:3662528 |
| Wanders RJ et al. | Peroxisomal fatty acid beta-oxidation in relation to the accumulation of very long chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders. | 1987 | J. Clin. Invest. | pmid:3680527 |