| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
| Diffuse Cerebral Sclerosis of Schilder | D002549 | 8 associated lipids |
| Abetalipoproteinemia | D000012 | 7 associated lipids |
| Sudden Infant Death | D013398 | 3 associated lipids |
Lignoceric acid
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
Cross Reference
Introduction
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lignoceric acid?
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lignoceric acid
PubChem Associated disorders and diseases
What pathways are associated with Lignoceric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lignoceric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lignoceric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lignoceric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lignoceric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lignoceric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lignoceric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Singh H et al. | Very long chain fatty acid beta-oxidation by subcellular fractions of normal and Zellweger syndrome skin fibroblasts. | 1987 | Arch. Biochem. Biophys. | pmid:3662528 |
| Bhushan A et al. | Characterization of rat brain microsomal acyl-coenzyme A ligases: different enzymes for the synthesis of palmitoyl-coenzyme A and lignoceroyl-coenzyme A. | 1986 | Arch. Biochem. Biophys. | pmid:3963826 |
| Tatsumi K et al. | Mechanism and stereospecificity of alpha-hydroxylation of lignoceric acid in rat brain. | 1975 | Arch. Biochem. Biophys. | pmid:1190799 |
| Cassagne C and Lessire R | Studies on alkane biosynthesis in epidermis of Allium porrum L. leaves. Direct synthesis of tricosane from lignoceric acid. | 1974 | Arch. Biochem. Biophys. | pmid:4441076 |
| Shimeno H et al. | Further characterization of the heat-stable factor in the alpha-hydroxylation and oxidation of lignoceric acid in brain: effect of acidic amino acids and hexose-phosphates on brain fatty acid metabolism. | 1983 | Arch. Biochem. Biophys. | pmid:6859867 |
| Uda M et al. | Purification of the heat-stable factor required for alpha-hydroxylation and beta-oxidation of very long chain fatty acids in brain. | 1982 | Arch. Biochem. Biophys. | pmid:7103506 |
| Bohn M et al. | Lipid composition and fluidity of plasma membranes isolated from corn (Zea mays L.) roots. | 2001 | Arch. Biochem. Biophys. | pmid:11368181 |
| Singh H et al. | Beta-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts. | 1987 | Arch. Biochem. Biophys. | pmid:2437859 |
| Hayashi H and Takahata S | Role of peroxisomal fatty acyl-CoA beta-oxidation in phospholipid biosynthesis. | 1991 | Arch. Biochem. Biophys. | pmid:1989516 |
| Lazo O et al. | Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. | 1989 | Arch. Biochem. Biophys. | pmid:2705786 |
| Elewaut D | Natural killer T cells and rheumatoid arthritis: friend or foe? | 2005 | Arthritis Res. Ther. | pmid:15743495 |
| Iida H et al. | Alterations in erythrocyte membrane lipids in abetalipoproteinemia: phospholipid and fatty acyl composition. | 1984 | Biochem Med | pmid:6497872 |
| Bourre JM et al. | Biosynthesis of lignoceric acid from behenyl0COA in mouse brain microsomes. Comparison between normal and Quaking mutant. | 1975 | Biochem. Biophys. Res. Commun. | pmid:236752 |
| Singh I and Kishimoto Y | A novel synthesis of ceramide from lignoceric acid and sphingosine by rat brain preparation; the amide formation requires a pyridine nucleotide. | 1978 | Biochem. Biophys. Res. Commun. | pmid:29620 |
| Aoyama T et al. | Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8024599 |
| Kawamura N et al. | Very long chain fatty acid oxidation in rat liver. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7259776 |
| Steinberg SJ et al. | Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10198260 |
| Soeda S et al. | Immobilization of fatty acyl-CoA synthetase: effect on its stability and substrate specificity. | 1986 | Biochem. Int. | pmid:3964283 |
| Street JM et al. | Metabolism of saturated and polyunsaturated very-long-chain fatty acids in fibroblasts from patients with defects in peroxisomal beta-oxidation. | 1990 | Biochem. J. | pmid:2117919 |
| GRAY GM | THE ISOLATION AND PARTIAL CHARACTERIZATION OF THE GLYCOLIPIDS OF BP8/C3H ASCITES-SARCOMA CELLS. | 1965 | Biochem. J. | pmid:14342256 |