| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sudden Infant Death | D013398 | 3 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
Lignoceric acid
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
Cross Reference
Introduction
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lignoceric acid?
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lignoceric acid
PubChem Associated disorders and diseases
What pathways are associated with Lignoceric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lignoceric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Lignoceric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lignoceric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lignoceric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Lignoceric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lignoceric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Singh I et al. | Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. | 1993 | Biochim. Biophys. Acta | pmid:8399326 |
| Bourre JM et al. | Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). | 1977 | Eur. J. Biochem. | pmid:836393 |
| Lageweg W and Wanders RJ | Studies on the effect of fenoprofen on the activation and oxidation of long chain and very long chain fatty acids in hepatocytes and subcellular fractions from rat liver. | 1993 | Biochem. Pharmacol. | pmid:8347139 |
| Bourre JM et al. | [Biosynthesis of lignoceric acid in two organelles (mitochondria and microsomes) during the development of the brain in normal and pathologic (Quaking and Jimpy) mice]. | 1976 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:825290 |
| Contreras M et al. | The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein. | 1994 | FEBS Lett. | pmid:8187886 |
| Bourre JM et al. | [Comparative biosynthesis of fatty acids, particularly lignoceric acid, in the kidney and brain of normal and "quaking" mice]. | 1976 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:817827 |
| Suzuki Y et al. | Prenatal diagnosis of peroxisomal disorders. Biochemical and immunocytochemical studies on peroxisomes in human amniocytes. | 1994 Jan-Feb | Brain Dev. | pmid:8059925 |
| Aoyama T et al. | Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8024599 |
| Hayashi H and Oohashi M | Incorporation of acetyl-CoA generated from peroxisomal beta-oxidation into ethanolamine plasmalogen of rat liver. | 1995 | Biochim. Biophys. Acta | pmid:7857972 |
| Dhaunsi GS et al. | Impairment of peroxisomal beta-oxidation system by endotoxin treatment. | 1994 | Mol. Cell. Biochem. | pmid:7838145 |
| Hashimoto F et al. | Effect of gemfibrozil on lipid biosynthesis from acetyl-CoA derived from peroxisomal beta-oxidation. | 1995 | Biochem. Pharmacol. | pmid:7763302 |
| Morrow MR et al. | Glycosphingolipid acyl chain order profiles: substituent effects. | 1995 | Biochim. Biophys. Acta | pmid:7756331 |
| Akanuma H and Kishimoto Y | Synthesis of ceramides and cerebrosides containing both alpha-hydroxy and nonhydroxy fatty acids from lignoceroyl-CoA by rat brain microsomes. | 1979 | J. Biol. Chem. | pmid:762114 |
| Singh I and Kishimoto Y | alpha-Hydroxylation of fatty acids in brain: characterization of heat-labile factor. | 1981 | J. Neurochem. | pmid:7264665 |
| Kawamura N et al. | Very long chain fatty acid oxidation in rat liver. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7259776 |
| Uda M et al. | Glutamate formed from lignoceric acid by rat brain preparation in the presence of pyridine nucleotide and cytosolic factors: a brain-specific oxidation of very long chain fatty acids. | 1981 | Biochemistry | pmid:7225329 |
| Singh I and Kishimoto Y | Brain-specific ceramide synthesis activity: change during brain maturation and in jimpy mouse brain. | 1982 | Brain Res. | pmid:7188035 |
| Rokukawa C et al. | Structural study on gangliosides from rat liver and erythrocytes. | 1982 | J. Biochem. | pmid:7153212 |
| Uda M et al. | Purification of the heat-stable factor required for alpha-hydroxylation and beta-oxidation of very long chain fatty acids in brain. | 1982 | Arch. Biochem. Biophys. | pmid:7103506 |
| Jaffe R et al. | Neonatal adrenoleukodystrophy: clinical, pathologic, and biochemical delineation of a syndrome affecting both males and females. | 1982 | Am. J. Pathol. | pmid:7091298 |