MeSH term | MeSH ID | Detail |
---|---|---|
Sudden Infant Death | D013398 | 3 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Metabolic Syndrome | D024821 | 44 associated lipids |
Polycystic Kidney Diseases | D007690 | 12 associated lipids |
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Lignoceric acid
MeSH term | MeSH ID | Detail |
---|---|---|
Sudden Infant Death | D013398 | 3 associated lipids |
Zellweger Syndrome | D015211 | 39 associated lipids |
Metabolic Syndrome | D024821 | 44 associated lipids |
Polycystic Kidney Diseases | D007690 | 12 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shimeno H et al. | Alpha-hydroxylation and oxidation of lignoceric acid in brain: the role of heat-stable and heat-labile factors. | 1984 | Neurochem. Res. | pmid:6738789 |
Takahashi M et al. | Phospholipid and fatty acid composition of erythrocyte membrane from wild Japanese serow (Capricornis crispus). | 1984 | Comp. Biochem. Physiol., B | pmid:6697694 |
Singh I et al. | Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy. | 1984 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6588384 |
Boiron F et al. | Decreased biosynthesis of saturated C20-C24 fatty acids by the trembler mouse sciatic nerve. | 1984 | Neurochem. Int. | pmid:20488028 |
Tsuji S et al. | Metabolism of [17,18-3H2]hexacosanoic acid and [15,16-3H2]lignoceric acid in cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). | 1985 | J. Neurol. Sci. | pmid:4087029 |
Mori MA et al. | Synthesis of ceramides and cerebrosides in rat brain: comparison with synthesis of lignoceroyl-coenzyme A. | 1985 | Neurochem. Int. | pmid:20492899 |
Singh I et al. | Lignoceroyl-CoA ligase activity in rat brain microsomal fraction: topographical localization and effect of detergents and alpha-cyclodextrin. | 1985 | Arch. Biochem. Biophys. | pmid:2578272 |
Crook SJ et al. | Factors affecting surface expression of glycolipids: influence of lipid environment and ceramide composition on antibody recognition of cerebroside sulfate in liposomes. | 1986 | Biochemistry | pmid:3801428 |
Singh H and Poulos A | A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. | 1986 | Arch. Biochem. Biophys. | pmid:3767370 |
Yoshida S and Takeshita M | Characteristics of synthesis of very-long-chain saturated and tetraenoic fatty acids in swine cerebral microsomes. | 1986 | J. Neurochem. | pmid:3958710 |