Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

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Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Sudden Infant Death D013398 3 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Hyperthyroidism D006980 12 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Refsum Disease D012035 19 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolic Syndrome D024821 44 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

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Per page 10 20 50 100 | Total 264
Authors Title Published Journal PubMed Link
Lazo O et al. Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3174658
Singh I et al. Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy. 1984 Proc. Natl. Acad. Sci. U.S.A. pmid:6588384
Khare G et al. Dissecting the role of critical residues and substrate preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis. 2009 PLoS ONE pmid:20027301
Devera TS et al. Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFNγ. 2011 PLoS ONE pmid:21858226
Assies J et al. Plasma and erythrocyte fatty acid patterns in patients with recurrent depression: a matched case-control study. 2010 PLoS ONE pmid:20498721
Bourdais A et al. Wood utilization is dependent on catalase activities in the filamentous fungus Podospora anserina. 2012 PLoS ONE pmid:22558065
Lü S et al. Arabidopsis ECERIFERUM9 involvement in cuticle formation and maintenance of plant water status. 2012 Plant Physiol. pmid:22635115
Kim J et al. Arabidopsis 3-ketoacyl-coenzyme a synthase9 is involved in the synthesis of tetracosanoic acids as precursors of cuticular waxes, suberins, sphingolipids, and phospholipids. 2013 Plant Physiol. pmid:23585652
Lytovchenko A et al. Application of GC-MS for the detection of lipophilic compounds in diverse plant tissues. 2009 Plant Methods pmid:19393072
Li H et al. Cytochrome P450 family member CYP704B2 catalyzes the {omega}-hydroxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice. 2010 Plant Cell pmid:20086189
Qin YM et al. Saturated very-long-chain fatty acids promote cotton fiber and Arabidopsis cell elongation by activating ethylene biosynthesis. 2007 Plant Cell pmid:17993622
Yao K et al. Expression of the Arabidopsis ADS1 gene in Brassica juncea results in a decreased level of total saturated fatty acids. 2003 Plant Biotechnol. J. pmid:17156034
Teponno RB et al. Bafoudiosbulbins A, and B, two anti-salmonellal clerodane diterpenoids from Dioscorea bulbifera L. var sativa. 2006 Phytochemistry pmid:16876211
Tresch S et al. Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. 2012 Phytochemistry pmid:22284369
Jetter R et al. Very long-chain phenylpropyl and phenylbutyl esters from Taxus baccata needle cuticular waxes. 2002 Phytochemistry pmid:12409026
Shimozawa N et al. Correction by gene expression of biochemical abnormalities in fibroblasts from Zellweger patients. 1996 Pediatr. Res. pmid:8726233
Aldámiz-Echevarría L et al. Persistence of essential fatty acid deficiency in cystic fibrosis despite nutritional therapy. 2009 Pediatr. Res. pmid:19851226
Chung HK et al. Plasma phospholipid arachidonic acid and lignoceric acid are associated with the risk of cardioembolic stroke. 2015 Nutr Res pmid:26452419
Hagfors L et al. Fat intake and composition of fatty acids in serum phospholipids in a randomized, controlled, Mediterranean dietary intervention study on patients with rheumatoid arthritis. 2005 Nutr Metab (Lond) pmid:16216119
Harnack K et al. Quantitation of alpha-linolenic acid elongation to eicosapentaenoic and docosahexaenoic acid as affected by the ratio of n6/n3 fatty acids. 2009 Nutr Metab (Lond) pmid:19228394