Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

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Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Sudden Infant Death D013398 3 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Hyperthyroidism D006980 12 associated lipids
Refsum Disease D012035 19 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolic Syndrome D024821 44 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

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Per page 10 20 50 100 | Total 264
Authors Title Published Journal PubMed Link
Wanders RJ et al. Peroxisomal very long-chain fatty acid beta-oxidation in human skin fibroblasts: activity in Zellweger syndrome and other peroxisomal disorders. 1987 Clin. Chim. Acta pmid:2441904
Song GY et al. High-fat feeding reduces endothelium-dependent vasodilation in rats: differential mechanisms for saturated and unsaturated fatty acids? 2006 Clin. Exp. Pharmacol. Physiol. pmid:16895544
Inoue K et al. Carrier identification of X-linked adrenoleukodystrophy by measurement of very long chain fatty acids and lignoceric acid oxidation. 1996 Clin. Genet. pmid:9007322
Poulos A et al. Accumulation and defective beta-oxidation of very long chain fatty acids in Zellweger's syndrome, adrenoleukodystrophy and Refsum's disease variants. 1986 Clin. Genet. pmid:2427264
Nasrallah F et al. X-linked Adrenoleukodystrophy, The Tunisian Experience. 2015 Clin. Lab. pmid:26642716
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Lederkremer RM and Bertello LE Glycoinositolphospholipids, free and as anchors of proteins, in Trypanosoma cruzi. 2001 Curr. Pharm. Des. pmid:11472260
Matsumori R et al. High levels of very long-chain saturated fatty acid in erythrocytes correlates with atherogenic lipoprotein profiles in subjects with metabolic syndrome. 2013 Diabetes Res. Clin. Pract. pmid:23146370
El-Shanawany MA et al. Stigmasterol Tetracosanoate, a New Stigmasterol Ester from the Egyptian Blepharis ciliaris. 2015 Drug Res (Stuttg) pmid:24992497
Kremser K et al. Nitric oxide regulates peroxisomal enzyme activities. 1995 Eur J Clin Chem Clin Biochem pmid:8620052
Lacave C et al. [Structural and metabolic study of the mycolic acids of Mycobacterium fortuitum]. 1987 Eur. J. Biochem. pmid:3816811
De Lederkremer RM et al. Lipopeptidophosphoglycan from Trypanosoma cruzi. Amide and ester-linked fatty acids. 1977 Eur. J. Biochem. pmid:323009
Bourre JM et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). 1977 Eur. J. Biochem. pmid:836393
Loureiro y Penha CV et al. Characterization of novel structures of mannosylinositolphosphorylceramides from the yeast forms of Sporothrix schenckii. 2001 Eur. J. Biochem. pmid:11488918
Jennemann R et al. Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus. 1999 Eur. J. Biochem. pmid:9914511
Denkberg G et al. Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules. 2008 Eur. J. Immunol. pmid:18253930
Stradomska TJ et al. Very long-chain fatty acids in Rett syndrome. 1999 Eur. J. Pediatr. pmid:10094444
Abdureyim S et al. Anti-inflammatory, immunomodulatory, and heme oxygenase-1 inhibitory activities of ravan napas, a formulation of uighur traditional medicine, in a rat model of allergic asthma. 2011 Evid Based Complement Alternat Med pmid:20953388
Rozema E et al. Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. 2012 Evid Based Complement Alternat Med pmid:22675394