| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sudden Infant Death | D013398 | 3 associated lipids |
| Abetalipoproteinemia | D000012 | 7 associated lipids |
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
| Diffuse Cerebral Sclerosis of Schilder | D002549 | 8 associated lipids |
| Hyperthyroidism | D006980 | 12 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
Lignoceric acid
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
Cross Reference
Introduction
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lignoceric acid?
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lignoceric acid
PubChem Associated disorders and diseases
What pathways are associated with Lignoceric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lignoceric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lignoceric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Lignoceric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Lignoceric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lignoceric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lignoceric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fretts AM et al. | Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. | 2016 | J. Nutr. | pmid:26701797 |
| Tsuji S et al. | Metabolism of [17,18-3H2]hexacosanoic acid and [15,16-3H2]lignoceric acid in cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). | 1985 | J. Neurol. Sci. | pmid:4087029 |
| Deon M et al. | The effect of Lorenzo's oil on oxidative stress in X-linked adrenoleukodystrophy. | 2006 | J. Neurol. Sci. | pmid:16750542 |
| Lazo O et al. | Postnatal development and isolation of peroxisomes from brain. | 1991 | J. Neurochem. | pmid:2002347 |
| Shigematsu H et al. | Purification and characterization of the heat-stable factors essential for the conversion of lignoceric acid to cerebronic acid and glutamic acid: identification of N-acetyl-L-aspartic acid. | 1983 | J. Neurochem. | pmid:6131106 |
| Singh H et al. | Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. | 1989 | J. Neurochem. | pmid:2809586 |
| Singh I and Kishimoto Y | alpha-Hydroxylation of fatty acids in brain: characterization of heat-labile factor. | 1981 | J. Neurochem. | pmid:7264665 |
| Yoshida S and Takeshita M | Characteristics of synthesis of very-long-chain saturated and tetraenoic fatty acids in swine cerebral microsomes. | 1986 | J. Neurochem. | pmid:3958710 |
| Singh I | Ceramide synthesis from free fatty acids in rat brain: function of NADPH and substrate specificity. | 1983 | J. Neurochem. | pmid:6854321 |
| Bentejac M et al. | Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. | 1989 | J. Neurochem. | pmid:2709013 |
| Harinantenaina L et al. | Secondary metabolites of Cinnamosma madagascariensis and their alpha-glucosidase inhibitory properties. | 2008 | J. Nat. Prod. | pmid:18179176 |
| Razani SH et al. | Fatty acid and carotenoid production by Sporobolomyces ruberrimus when using technical glycerol and ammonium sulfate. | 2007 | J. Microbiol. Biotechnol. | pmid:18156773 |
| Kusunoki M et al. | Relationship between serum concentrations of saturated fatty acids and unsaturated fatty acids and the homeostasis model insulin resistance index in Japanese patients with type 2 diabetes mellitus. | 2007 | J. Med. Invest. | pmid:17878672 |
| Fabiano A et al. | Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. | 2011 | J. Matern. Fetal. Neonatal. Med. | pmid:21781003 |
| Ohta M et al. | Novel free ceramides as components of the soldier defense gland of the Formosan subterranean termite (Coptotermes formosanus). | 2007 | J. Lipid Res. | pmid:17164223 |
| Robert J et al. | Glycosphingolipids from cultured astroblasts. | 1977 | J. Lipid Res. | pmid:894142 |
| Singh I and Kishimoto Y | Effect of cyclodextrins on the solubilization of lignoceric acid, ceramide, and cerebroside, and on the enzymatic reactions involving these compounds. | 1983 | J. Lipid Res. | pmid:6875391 |
| Sandhir R et al. | Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. | 1998 | J. Lipid Res. | pmid:9799802 |
| Alderson NL et al. | A novel method for the measurement of in vitro fatty acid 2-hydroxylase activity by gas chromatography-mass spectrometry. | 2005 | J. Lipid Res. | pmid:15863841 |
| Lazo O et al. | Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. | 1990 | J. Lipid Res. | pmid:2141053 |