Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

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Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Sudden Infant Death D013398 3 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Hyperthyroidism D006980 12 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Refsum Disease D012035 19 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Metabolic Syndrome D024821 44 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Fretts AM et al. Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. 2016 J. Nutr. pmid:26701797
Tsuji S et al. Metabolism of [17,18-3H2]hexacosanoic acid and [15,16-3H2]lignoceric acid in cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). 1985 J. Neurol. Sci. pmid:4087029
Deon M et al. The effect of Lorenzo's oil on oxidative stress in X-linked adrenoleukodystrophy. 2006 J. Neurol. Sci. pmid:16750542
Lazo O et al. Postnatal development and isolation of peroxisomes from brain. 1991 J. Neurochem. pmid:2002347
Shigematsu H et al. Purification and characterization of the heat-stable factors essential for the conversion of lignoceric acid to cerebronic acid and glutamic acid: identification of N-acetyl-L-aspartic acid. 1983 J. Neurochem. pmid:6131106
Singh H et al. Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. 1989 J. Neurochem. pmid:2809586
Singh I and Kishimoto Y alpha-Hydroxylation of fatty acids in brain: characterization of heat-labile factor. 1981 J. Neurochem. pmid:7264665
Yoshida S and Takeshita M Characteristics of synthesis of very-long-chain saturated and tetraenoic fatty acids in swine cerebral microsomes. 1986 J. Neurochem. pmid:3958710
Singh I Ceramide synthesis from free fatty acids in rat brain: function of NADPH and substrate specificity. 1983 J. Neurochem. pmid:6854321
Bentejac M et al. Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. 1989 J. Neurochem. pmid:2709013