| MeSH term | MeSH ID | Detail |
|---|---|---|
| Reperfusion Injury | D015427 | 65 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Diffuse Cerebral Sclerosis of Schilder | D002549 | 8 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Hyperthyroidism | D006980 | 12 associated lipids |
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
| Abetalipoproteinemia | D000012 | 7 associated lipids |
Lignoceric acid
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
Cross Reference
Introduction
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lignoceric acid?
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lignoceric acid
PubChem Associated disorders and diseases
What pathways are associated with Lignoceric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lignoceric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lignoceric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Lignoceric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Lignoceric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lignoceric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lignoceric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Deon M et al. | The effect of Lorenzo's oil on oxidative stress in X-linked adrenoleukodystrophy. | 2006 | J. Neurol. Sci. | pmid:16750542 |
| Dhaunsi GS et al. | Very long chain fatty acids activate NADPH oxidase in human dermal fibroblasts. | 2005 Jan-Feb | Cell Biochem. Funct. | pmid:15565636 |
| Hall AM et al. | Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice. | 2005 | J. Biol. Chem. | pmid:15653672 |
| Salas JJ et al. | Very long chain fatty acid synthesis in sunflower kernels. | 2005 | J. Agric. Food Chem. | pmid:15796615 |
| Dhaunsi GS et al. | Very-long-chain fatty acids activate lysosomal hydrolases in neonatal human skin tissue. | 2005 | Med Princ Pract | pmid:16103719 |
| Alderson NL et al. | A novel method for the measurement of in vitro fatty acid 2-hydroxylase activity by gas chromatography-mass spectrometry. | 2005 | J. Lipid Res. | pmid:15863841 |
| Costachel C et al. | Glycosylphosphatidylinositol-anchored fungal polysaccharide in Aspergillus fumigatus. | 2005 | J. Biol. Chem. | pmid:16204227 |
| Ndonye RM et al. | Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH. | 2005 | J. Org. Chem. | pmid:16323834 |
| Hagfors L et al. | Fat intake and composition of fatty acids in serum phospholipids in a randomized, controlled, Mediterranean dietary intervention study on patients with rheumatoid arthritis. | 2005 | Nutr Metab (Lond) | pmid:16216119 |
| Oki S et al. | Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. | 2005 | Int. Immunol. | pmid:16291659 |
| Lücker E et al. | Transmissible spongiform encephalopathies: assessment of exposure risk in the histological working environment using GC-MS detection of fatty acids as marker for central nervous tissues. | 2005 | Int J Hyg Environ Health | pmid:16217923 |
| Elewaut D | Natural killer T cells and rheumatoid arthritis: friend or foe? | 2005 | Arthritis Res. Ther. | pmid:15743495 |
| Dhaunsi GS and Bitar MS | Antioxidants attenuate diabetes-induced activation of peroxisomal functions in the rat kidney. | 2004 Sep-Oct | J. Biomed. Sci. | pmid:15316130 |
| Vargas CR et al. | Evidence that oxidative stress is increased in patients with X-linked adrenoleukodystrophy. | 2004 | Biochim. Biophys. Acta | pmid:14732478 |
| Nagura M et al. | Alterations of fatty acid metabolism and membrane fluidity in peroxisome-defective mutant ZP102 cells. | 2004 | Lipids | pmid:15055234 |
| Zhang YH et al. | Structural elucidation of fritillahupehin from bulbs of Fritillaria hupehensis Hsiao et K.C. Hsia. | 2004 | J Asian Nat Prod Res | pmid:14989377 |
| Kemp S et al. | Method for measurement of peroxisomal very-long-chain fatty acid beta-oxidation in human skin fibroblasts using stable-isotope-labeled tetracosanoic acid. | 2004 | Clin. Chem. | pmid:15388659 |
| Nagy K et al. | An HPLC-MS approach for analysis of very long chain fatty acids and other apolar compounds on octadecyl-silica phase using partly miscible solvents. | 2004 | Anal. Chem. | pmid:15053654 |
| Mizuno M et al. | Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice. | 2004 | J. Autoimmun. | pmid:15571923 |
| Alderson NL et al. | The human FA2H gene encodes a fatty acid 2-hydroxylase. | 2004 | J. Biol. Chem. | pmid:15337768 |
| Cimini A et al. | TNFalpha downregulates PPARdelta expression in oligodendrocyte progenitor cells: implications for demyelinating diseases. | 2003 | Glia | pmid:12465041 |
| Hall AM et al. | Characterization of the Acyl-CoA synthetase activity of purified murine fatty acid transport protein 1. | 2003 | J. Biol. Chem. | pmid:12937175 |
| Petroni A et al. | Effects of the testosterone metabolite dihydrotestosterone and 5 alpha-androstan-3 alpha,17 beta-diol on very long chain fatty acid metabolism in X-adrenoleukodystrophic fibroblasts. | 2003 | Life Sci. | pmid:12865096 |
| Agazzi ME et al. | In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products. | 2003 | Anal Bioanal Chem | pmid:12732919 |
| Nelson DR et al. | Characterization of the cuticular surface wax pores and the waxy particles of the dustywing, Semidalis flinti (Neuroptera: Coniopterygidae). | 2003 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:14529760 |
| Yao K et al. | Expression of the Arabidopsis ADS1 gene in Brassica juncea results in a decreased level of total saturated fatty acids. | 2003 | Plant Biotechnol. J. | pmid:17156034 |
| Chavez JA and Summers SA | Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. | 2003 | Arch. Biochem. Biophys. | pmid:14592453 |
| Singh I | Peroxisomal fatty acid oxidation and cellular redox. | 2002 | Meth. Enzymol. | pmid:12125363 |
| Ruan H et al. | Structure of a novel diterpenoid ester, fritillahupehin from bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. | 2002 | Fitoterapia | pmid:12234570 |
| Qiao CF et al. | [Studies on chemical constituents of two plants from Costus]. | 2002 | Zhongguo Zhong Yao Za Zhi | pmid:12774385 |
| O'Neill W et al. | Flaxseed (Linum usitatissimum) supplementation associated with reduced skin test lesional area in horses with Culicoides hypersensitivity. | 2002 | Can. J. Vet. Res. | pmid:12418783 |
| Jetter R et al. | Very long-chain phenylpropyl and phenylbutyl esters from Taxus baccata needle cuticular waxes. | 2002 | Phytochemistry | pmid:12409026 |
| Xiang W et al. | Constituents of Gnetum montanum. | 2002 | Fitoterapia | pmid:11864762 |
| Tomosaka H et al. | Lupeol esters from the twig bark of Japanese pear (Pyrus serotina Rehd.) cv. Shinko. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11440139 |
| Loureiro y Penha CV et al. | Characterization of novel structures of mannosylinositolphosphorylceramides from the yeast forms of Sporothrix schenckii. | 2001 | Eur. J. Biochem. | pmid:11488918 |
| Dvoráková L et al. | Eight novel ABCD1 gene mutations and three polymorphisms in patients with X-linked adrenoleukodystrophy: The first polymorphism causing an amino acid exchange. | 2001 | Hum. Mutat. | pmid:11438993 |
| Takamoto DY et al. | Stable ordering in Langmuir-Blodgett films. | 2001 | Science | pmid:11509723 |
| Lederkremer RM and Bertello LE | Glycoinositolphospholipids, free and as anchors of proteins, in Trypanosoma cruzi. | 2001 | Curr. Pharm. Des. | pmid:11472260 |
| Bohn M et al. | Lipid composition and fluidity of plasma membranes isolated from corn (Zea mays L.) roots. | 2001 | Arch. Biochem. Biophys. | pmid:11368181 |
| Zhang JH et al. | [Studies on the chemical constituents from Sophora flavescens ait]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12205972 |
| Li ZP et al. | [Studies on chemical constituents from the flower of Albizzia julibrissin Durazz]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12212069 |
| Singh I et al. | Isolation and biochemical characterization of peroxisomes from cultured rat glial cells. | 2000 | Neurochem. Res. | pmid:10786702 |
| Di Marino L et al. | Is the erythrocyte membrane fatty acid composition a valid index of skeletal muscle membrane fatty acid composition? | 2000 | Metab. Clin. Exp. | pmid:11016898 |
| Petroni A et al. | Testosterone metabolites in patients reduce the levels of very long chain fatty acids accumulated in X-adrenoleukodystrophic fibroblasts. | 2000 | Neurosci. Lett. | pmid:10904139 |
| Vilchèze C et al. | Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis. | 2000 | J. Bacteriol. | pmid:10869086 |
| Stradomska TJ et al. | Very long-chain fatty acids in Rett syndrome. | 1999 | Eur. J. Pediatr. | pmid:10094444 |
| Steinberg SJ et al. | Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10198260 |
| Poulos A et al. | Metabolism of trideuterated iso-lignoceric acid in rats in vivo and in human fibroblasts in culture. | 1999 | Lipids | pmid:10574659 |
| Jennemann R et al. | Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus. | 1999 | Eur. J. Biochem. | pmid:9914511 |
| Sandhir R et al. | Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. | 1998 | J. Lipid Res. | pmid:9799802 |
| Singh I et al. | Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. | 1998 | FEBS Lett. | pmid:9600263 |
| Suzuki Y et al. | D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: a newly identified peroxisomal disorder. | 1997 | Am. J. Hum. Genet. | pmid:9345094 |
| Hayashi H and Hara M | 1-Alkenyl group of ethanolamine plasmalogen derives mainly from de novo-synthesized fatty alcohol within peroxisomes, but not extraperoxisomal fatty alcohol or fatty acid. | 1997 | J. Biochem. | pmid:9192743 |
| Bettger WJ and Blackadar CB | Dietary very long chain fatty acids directly influence the ratio of tetracosenoic (24:1) to tetracosanoic (24:0) acids of sphingomyelin in rat liver. | 1997 | Lipids | pmid:9075193 |
| Suzuki Y et al. | Biochemical and immunocytochemical properties of peroxisomes and mitochondria in bovine chromaffin cells. | 1997 | Cell Struct. Funct. | pmid:9591053 |
| Dawson G et al. | Mitochondrial abnormalities in CLN2 and CLN3 forms of Batten disease. | 1996 Oct-Dec | Mol. Chem. Neuropathol. | pmid:8971698 |
| Aveldaño MI and Donnari D | Plasma phospholipid fatty acids in X-linked adrenoleukodystrophy. | 1996 | Clin. Chem. | pmid:8598113 |
| Burdette DE et al. | Late-onset generalized disorder of peroxisomes. | 1996 | Neurology | pmid:8618694 |
| Shimozawa N et al. | Correction by gene expression of biochemical abnormalities in fibroblasts from Zellweger patients. | 1996 | Pediatr. Res. | pmid:8726233 |
| ten Grotenhuis E et al. | Phase behavior of stratum corneum lipids in mixed Langmuir-Blodgett monolayers. | 1996 | Biophys. J. | pmid:8874014 |
| Inoue K et al. | Carrier identification of X-linked adrenoleukodystrophy by measurement of very long chain fatty acids and lignoceric acid oxidation. | 1996 | Clin. Genet. | pmid:9007322 |
| Morrow MR et al. | Glycosphingolipid acyl chain order profiles: substituent effects. | 1995 | Biochim. Biophys. Acta | pmid:7756331 |
| Hayashi H and Oohashi M | Incorporation of acetyl-CoA generated from peroxisomal beta-oxidation into ethanolamine plasmalogen of rat liver. | 1995 | Biochim. Biophys. Acta | pmid:7857972 |
| Hashimoto F et al. | Effect of gemfibrozil on lipid biosynthesis from acetyl-CoA derived from peroxisomal beta-oxidation. | 1995 | Biochem. Pharmacol. | pmid:7763302 |
| Maulik PR and Shipley GG | X-ray diffraction and calorimetric study of N-lignoceryl sphingomyelin membranes. | 1995 | Biophys. J. | pmid:8580334 |
| Kremser K et al. | Nitric oxide regulates peroxisomal enzyme activities. | 1995 | Eur J Clin Chem Clin Biochem | pmid:8620052 |
| Suzuki Y et al. | Prenatal diagnosis of peroxisomal disorders. Biochemical and immunocytochemical studies on peroxisomes in human amniocytes. | 1994 Jan-Feb | Brain Dev. | pmid:8059925 |
| Dhaunsi GS et al. | Impairment of peroxisomal beta-oxidation system by endotoxin treatment. | 1994 | Mol. Cell. Biochem. | pmid:7838145 |
| Aoyama T et al. | Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8024599 |
| Contreras M et al. | The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein. | 1994 | FEBS Lett. | pmid:8187886 |
| Singh I et al. | Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. | 1993 | Biochim. Biophys. Acta | pmid:8399326 |
| Gulati S et al. | Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. | 1993 | Biochim. Biophys. Acta | pmid:8399363 |
| Lu D et al. | Effect of glycosphingolipid fatty acid chain length on behavior in unsaturated phosphatidylcholine bilayers: a 2H NMR study. | 1993 | Biochemistry | pmid:8418849 |
| Singh I et al. | Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz. | 1993 | J. Biol. Chem. | pmid:8486724 |
| Lageweg W and Wanders RJ | Studies on the effect of fenoprofen on the activation and oxidation of long chain and very long chain fatty acids in hepatocytes and subcellular fractions from rat liver. | 1993 | Biochem. Pharmacol. | pmid:8347139 |
| Boles DJ and Rizzo WB | Dietary fatty acids temporarily alter liver very long-chain fatty acid composition in mice. | 1992 | J. Nutr. | pmid:1640260 |
| Okamoto H et al. | Transformation and characterization of mutant human fibroblasts defective in peroxisome assembly. | 1992 | Exp. Cell Res. | pmid:1639130 |
| Stanczak H et al. | Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes. | 1992 | Hum. Hered. | pmid:1511996 |
| Singh I et al. | Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy. | 1992 | J. Biol. Chem. | pmid:1618832 |
| Gulati S et al. | Ischemia-reperfusion injury: biochemical alterations in peroxisomes of rat kidney. | 1992 | Arch. Biochem. Biophys. | pmid:1575521 |
| Lazo O et al. | Postnatal development and isolation of peroxisomes from brain. | 1991 | J. Neurochem. | pmid:2002347 |
| Reubsaet FA et al. | Immunochemical and biochemical studies of fatty acid oxidation in fibroblasts of Zellweger and X-linked adrenoleukodystrophy patients. | 1991 | Biochim. Biophys. Acta | pmid:2049396 |
| Hayashi H and Takahata S | Role of peroxisomal fatty acyl-CoA beta-oxidation in phospholipid biosynthesis. | 1991 | Arch. Biochem. Biophys. | pmid:1989516 |
| Lazo O et al. | Effect of ciprofibrate on the activation and oxidation of very long chain fatty acids. | 1991 | Mol. Cell. Biochem. | pmid:2008177 |
| Dhaunsi GS et al. | Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats. | 1990 | J. Exp. Pathol. | pmid:2101135 |
| Bentejac M et al. | Time-course of utilization of [stearic or lignoceric acid]sphingomyelin from high-density lipoprotein by rat tissues. | 1990 | Biochim. Biophys. Acta | pmid:2317523 |
| Street JM et al. | Metabolism of saturated and polyunsaturated very-long-chain fatty acids in fibroblasts from patients with defects in peroxisomal beta-oxidation. | 1990 | Biochem. J. | pmid:2117919 |
| Lazo O et al. | Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. | 1990 | J. Lipid Res. | pmid:2141053 |
| Iida N et al. | A sulfated glucosylceramide from rat kidney. | 1989 | J. Biol. Chem. | pmid:2925645 |
| Carneheim C et al. | Rare fatty acids in brown fat are substrates for thermogenesis during arousal from hibernation. | 1989 | Am. J. Physiol. | pmid:2912207 |
| Singh H et al. | Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. | 1989 | J. Neurochem. | pmid:2809586 |
| Bentejac M et al. | Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. | 1989 | J. Neurochem. | pmid:2709013 |
| Jantzen E et al. | Gas chromatography of mycobacterial fatty acids and alcohols: diagnostic applications. | 1989 | APMIS | pmid:2590535 |
| Xie JM et al. | [Studies on the chemical constituents of Excoecaria cochinchinensis Lour. var. viridis Merr]. | 1989 | Zhongguo Zhong Yao Za Zhi | pmid:2512946 |
| Tanaka K et al. | Very long-chain fatty acids in erythrocyte membrane phospholipids in adrenoleukodystrophy. | 1989 | Acta Paediatr Jpn | pmid:2516693 |
| Lazo O et al. | Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. | 1989 | Arch. Biochem. Biophys. | pmid:2705786 |
| Poll-The BT et al. | A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy). | 1988 | Am. J. Hum. Genet. | pmid:2894756 |
| Wanders RJ et al. | Impaired ability of peroxisomes to activate very-long-chain fatty acids in X-linked adrenoleukodystrophy. | 1988 | Lancet | pmid:2899227 |
| Singh I et al. | Acyl-CoA ligases from rat brain microsomes: an immunochemical study. | 1988 | Biochim. Biophys. Acta | pmid:2973813 |
| Lazo O et al. | Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3174658 |