| MeSH term | MeSH ID | Detail |
|---|---|---|
| Reperfusion Injury | D015427 | 65 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Diffuse Cerebral Sclerosis of Schilder | D002549 | 8 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Hyperthyroidism | D006980 | 12 associated lipids |
| Chondrodysplasia Punctata | D002806 | 8 associated lipids |
| Abetalipoproteinemia | D000012 | 7 associated lipids |
Lignoceric acid
Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.
Cross Reference
Introduction
To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lignoceric acid?
Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lignoceric acid
PubChem Associated disorders and diseases
What pathways are associated with Lignoceric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lignoceric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Lignoceric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lignoceric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lignoceric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Lignoceric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Lignoceric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hashimoto F et al. | Effect of gemfibrozil on lipid biosynthesis from acetyl-CoA derived from peroxisomal beta-oxidation. | 1995 | Biochem. Pharmacol. | pmid:7763302 |
| Lageweg W and Wanders RJ | Studies on the effect of fenoprofen on the activation and oxidation of long chain and very long chain fatty acids in hepatocytes and subcellular fractions from rat liver. | 1993 | Biochem. Pharmacol. | pmid:8347139 |
| Crook SJ et al. | Factors affecting surface expression of glycolipids: influence of lipid environment and ceramide composition on antibody recognition of cerebroside sulfate in liposomes. | 1986 | Biochemistry | pmid:3801428 |
| Lu D et al. | Effect of glycosphingolipid fatty acid chain length on behavior in unsaturated phosphatidylcholine bilayers: a 2H NMR study. | 1993 | Biochemistry | pmid:8418849 |
| Uda M et al. | Glutamate formed from lignoceric acid by rat brain preparation in the presence of pyridine nucleotide and cytosolic factors: a brain-specific oxidation of very long chain fatty acids. | 1981 | Biochemistry | pmid:7225329 |
| Wanders RJ et al. | Studies on the peroxisomal oxidation of palmitate and lignocerate in rat liver. | 1987 | Biochim. Biophys. Acta | pmid:2952173 |
| Singh I et al. | Acyl-CoA ligases from rat brain microsomes: an immunochemical study. | 1988 | Biochim. Biophys. Acta | pmid:2973813 |
| Morrow MR et al. | Glycosphingolipid acyl chain order profiles: substituent effects. | 1995 | Biochim. Biophys. Acta | pmid:7756331 |
| Veerkamp JH and van Moerkerk HT | Peroxisomal fatty acid oxidation in rat and human tissues. Effect of nutritional state, clofibrate treatment and postnatal development in the rat. | 1986 | Biochim. Biophys. Acta | pmid:3942767 |
| Vargas CR et al. | Evidence that oxidative stress is increased in patients with X-linked adrenoleukodystrophy. | 2004 | Biochim. Biophys. Acta | pmid:14732478 |
| Hayashi H and Oohashi M | Incorporation of acetyl-CoA generated from peroxisomal beta-oxidation into ethanolamine plasmalogen of rat liver. | 1995 | Biochim. Biophys. Acta | pmid:7857972 |
| Singh I et al. | Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. | 1993 | Biochim. Biophys. Acta | pmid:8399326 |
| Gulati S et al. | Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. | 1993 | Biochim. Biophys. Acta | pmid:8399363 |
| Oguri M et al. | The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes. | 2014 | Biochim. Biophys. Acta | pmid:24565794 |
| DiRusso CC et al. | Functional domains of the fatty acid transport proteins: studies using protein chimeras. | 2008 | Biochim. Biophys. Acta | pmid:18258213 |
| Reubsaet FA et al. | Immunochemical and biochemical studies of fatty acid oxidation in fibroblasts of Zellweger and X-linked adrenoleukodystrophy patients. | 1991 | Biochim. Biophys. Acta | pmid:2049396 |
| Bentejac M et al. | Time-course of utilization of [stearic or lignoceric acid]sphingomyelin from high-density lipoprotein by rat tissues. | 1990 | Biochim. Biophys. Acta | pmid:2317523 |
| Veerapen N et al. | Synthesis and biological activity of alpha-L-fucosyl ceramides, analogues of the potent agonist, alpha-D-galactosyl ceramide KRN7000. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20462758 |
| Pullmannová P et al. | Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. | 2017 | Biophys. Chem. | pmid:28363088 |
| Mojumdar EH et al. | Localization of cholesterol and fatty acid in a model lipid membrane: a neutron diffraction approach. | 2013 | Biophys. J. | pmid:23972843 |