Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

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Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperthyroidism D006980 12 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

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Per page 10 20 50 100 | Total 264
Authors Title Published Journal PubMed Link
Wanders RJ et al. Peroxisomal fatty acid beta-oxidation in relation to the accumulation of very long chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders. 1987 J. Clin. Invest. pmid:3680527
Tanaka K et al. Electronmicroscopic study on biopsied rectal mucosa in adrenoleukodystrophy. 1987 Neurology pmid:3587618
Singh H et al. Very long chain fatty acid beta-oxidation by subcellular fractions of normal and Zellweger syndrome skin fibroblasts. 1987 Arch. Biochem. Biophys. pmid:3662528
Singh H et al. Beta-oxidation of very-long-chain fatty acids and their coenzyme A derivatives by human skin fibroblasts. 1987 Arch. Biochem. Biophys. pmid:2437859
Poll-The BT et al. A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy). 1988 Am. J. Hum. Genet. pmid:2894756
Wanders RJ et al. Impaired ability of peroxisomes to activate very-long-chain fatty acids in X-linked adrenoleukodystrophy. 1988 Lancet pmid:2899227
Singh I et al. Acyl-CoA ligases from rat brain microsomes: an immunochemical study. 1988 Biochim. Biophys. Acta pmid:2973813
Lazo O et al. Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3174658
Iida N et al. A sulfated glucosylceramide from rat kidney. 1989 J. Biol. Chem. pmid:2925645
Carneheim C et al. Rare fatty acids in brown fat are substrates for thermogenesis during arousal from hibernation. 1989 Am. J. Physiol. pmid:2912207
Singh H et al. Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. 1989 J. Neurochem. pmid:2809586
Bentejac M et al. Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. 1989 J. Neurochem. pmid:2709013
Jantzen E et al. Gas chromatography of mycobacterial fatty acids and alcohols: diagnostic applications. 1989 APMIS pmid:2590535
Xie JM et al. [Studies on the chemical constituents of Excoecaria cochinchinensis Lour. var. viridis Merr]. 1989 Zhongguo Zhong Yao Za Zhi pmid:2512946
Tanaka K et al. Very long-chain fatty acids in erythrocyte membrane phospholipids in adrenoleukodystrophy. 1989 Acta Paediatr Jpn pmid:2516693
Lazo O et al. Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. 1989 Arch. Biochem. Biophys. pmid:2705786
Dhaunsi GS et al. Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats. 1990 J. Exp. Pathol. pmid:2101135
Bentejac M et al. Time-course of utilization of [stearic or lignoceric acid]sphingomyelin from high-density lipoprotein by rat tissues. 1990 Biochim. Biophys. Acta pmid:2317523
Street JM et al. Metabolism of saturated and polyunsaturated very-long-chain fatty acids in fibroblasts from patients with defects in peroxisomal beta-oxidation. 1990 Biochem. J. pmid:2117919
Lazo O et al. Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. 1990 J. Lipid Res. pmid:2141053