Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

Cross Reference

Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperthyroidism D006980 12 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

Download all related citations
Per page 10 20 50 100 | Total 264
Authors Title Published Journal PubMed Link
Singh I et al. Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. 1998 FEBS Lett. pmid:9600263
Suzuki Y et al. D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: a newly identified peroxisomal disorder. 1997 Am. J. Hum. Genet. pmid:9345094
Hayashi H and Hara M 1-Alkenyl group of ethanolamine plasmalogen derives mainly from de novo-synthesized fatty alcohol within peroxisomes, but not extraperoxisomal fatty alcohol or fatty acid. 1997 J. Biochem. pmid:9192743
Bettger WJ and Blackadar CB Dietary very long chain fatty acids directly influence the ratio of tetracosenoic (24:1) to tetracosanoic (24:0) acids of sphingomyelin in rat liver. 1997 Lipids pmid:9075193
Suzuki Y et al. Biochemical and immunocytochemical properties of peroxisomes and mitochondria in bovine chromaffin cells. 1997 Cell Struct. Funct. pmid:9591053
Dawson G et al. Mitochondrial abnormalities in CLN2 and CLN3 forms of Batten disease. 1996 Oct-Dec Mol. Chem. Neuropathol. pmid:8971698
Aveldaño MI and Donnari D Plasma phospholipid fatty acids in X-linked adrenoleukodystrophy. 1996 Clin. Chem. pmid:8598113
Burdette DE et al. Late-onset generalized disorder of peroxisomes. 1996 Neurology pmid:8618694
Shimozawa N et al. Correction by gene expression of biochemical abnormalities in fibroblasts from Zellweger patients. 1996 Pediatr. Res. pmid:8726233
ten Grotenhuis E et al. Phase behavior of stratum corneum lipids in mixed Langmuir-Blodgett monolayers. 1996 Biophys. J. pmid:8874014
Inoue K et al. Carrier identification of X-linked adrenoleukodystrophy by measurement of very long chain fatty acids and lignoceric acid oxidation. 1996 Clin. Genet. pmid:9007322
Morrow MR et al. Glycosphingolipid acyl chain order profiles: substituent effects. 1995 Biochim. Biophys. Acta pmid:7756331
Hayashi H and Oohashi M Incorporation of acetyl-CoA generated from peroxisomal beta-oxidation into ethanolamine plasmalogen of rat liver. 1995 Biochim. Biophys. Acta pmid:7857972
Hashimoto F et al. Effect of gemfibrozil on lipid biosynthesis from acetyl-CoA derived from peroxisomal beta-oxidation. 1995 Biochem. Pharmacol. pmid:7763302
Maulik PR and Shipley GG X-ray diffraction and calorimetric study of N-lignoceryl sphingomyelin membranes. 1995 Biophys. J. pmid:8580334
Kremser K et al. Nitric oxide regulates peroxisomal enzyme activities. 1995 Eur J Clin Chem Clin Biochem pmid:8620052
Suzuki Y et al. Prenatal diagnosis of peroxisomal disorders. Biochemical and immunocytochemical studies on peroxisomes in human amniocytes. 1994 Jan-Feb Brain Dev. pmid:8059925
Dhaunsi GS et al. Impairment of peroxisomal beta-oxidation system by endotoxin treatment. 1994 Mol. Cell. Biochem. pmid:7838145
Aoyama T et al. Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system. 1994 Biochem. Biophys. Res. Commun. pmid:8024599
Contreras M et al. The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein. 1994 FEBS Lett. pmid:8187886
Singh I et al. Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. 1993 Biochim. Biophys. Acta pmid:8399326
Gulati S et al. Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. 1993 Biochim. Biophys. Acta pmid:8399363
Lu D et al. Effect of glycosphingolipid fatty acid chain length on behavior in unsaturated phosphatidylcholine bilayers: a 2H NMR study. 1993 Biochemistry pmid:8418849
Singh I et al. Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz. 1993 J. Biol. Chem. pmid:8486724
Lageweg W and Wanders RJ Studies on the effect of fenoprofen on the activation and oxidation of long chain and very long chain fatty acids in hepatocytes and subcellular fractions from rat liver. 1993 Biochem. Pharmacol. pmid:8347139
Boles DJ and Rizzo WB Dietary fatty acids temporarily alter liver very long-chain fatty acid composition in mice. 1992 J. Nutr. pmid:1640260
Okamoto H et al. Transformation and characterization of mutant human fibroblasts defective in peroxisome assembly. 1992 Exp. Cell Res. pmid:1639130
Stanczak H et al. Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes. 1992 Hum. Hered. pmid:1511996
Singh I et al. Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy. 1992 J. Biol. Chem. pmid:1618832
Gulati S et al. Ischemia-reperfusion injury: biochemical alterations in peroxisomes of rat kidney. 1992 Arch. Biochem. Biophys. pmid:1575521
Lazo O et al. Postnatal development and isolation of peroxisomes from brain. 1991 J. Neurochem. pmid:2002347
Reubsaet FA et al. Immunochemical and biochemical studies of fatty acid oxidation in fibroblasts of Zellweger and X-linked adrenoleukodystrophy patients. 1991 Biochim. Biophys. Acta pmid:2049396
Hayashi H and Takahata S Role of peroxisomal fatty acyl-CoA beta-oxidation in phospholipid biosynthesis. 1991 Arch. Biochem. Biophys. pmid:1989516
Lazo O et al. Effect of ciprofibrate on the activation and oxidation of very long chain fatty acids. 1991 Mol. Cell. Biochem. pmid:2008177
Dhaunsi GS et al. Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats. 1990 J. Exp. Pathol. pmid:2101135
Bentejac M et al. Time-course of utilization of [stearic or lignoceric acid]sphingomyelin from high-density lipoprotein by rat tissues. 1990 Biochim. Biophys. Acta pmid:2317523
Street JM et al. Metabolism of saturated and polyunsaturated very-long-chain fatty acids in fibroblasts from patients with defects in peroxisomal beta-oxidation. 1990 Biochem. J. pmid:2117919
Lazo O et al. Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. 1990 J. Lipid Res. pmid:2141053
Iida N et al. A sulfated glucosylceramide from rat kidney. 1989 J. Biol. Chem. pmid:2925645
Carneheim C et al. Rare fatty acids in brown fat are substrates for thermogenesis during arousal from hibernation. 1989 Am. J. Physiol. pmid:2912207
Singh H et al. Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. 1989 J. Neurochem. pmid:2809586
Bentejac M et al. Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. 1989 J. Neurochem. pmid:2709013
Jantzen E et al. Gas chromatography of mycobacterial fatty acids and alcohols: diagnostic applications. 1989 APMIS pmid:2590535
Xie JM et al. [Studies on the chemical constituents of Excoecaria cochinchinensis Lour. var. viridis Merr]. 1989 Zhongguo Zhong Yao Za Zhi pmid:2512946
Tanaka K et al. Very long-chain fatty acids in erythrocyte membrane phospholipids in adrenoleukodystrophy. 1989 Acta Paediatr Jpn pmid:2516693
Lazo O et al. Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. 1989 Arch. Biochem. Biophys. pmid:2705786
Poll-The BT et al. A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy). 1988 Am. J. Hum. Genet. pmid:2894756
Wanders RJ et al. Impaired ability of peroxisomes to activate very-long-chain fatty acids in X-linked adrenoleukodystrophy. 1988 Lancet pmid:2899227
Singh I et al. Acyl-CoA ligases from rat brain microsomes: an immunochemical study. 1988 Biochim. Biophys. Acta pmid:2973813
Lazo O et al. Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3174658