Lignoceric acid

Lignoceric acid is a lipid of Fatty Acyls (FA) class. Lignoceric acid is associated with abnormalities such as Adrenoleukodystrophy and Peroxisomal Disorders. The involved functions are known as Anabolism, establishment and maintenance of localization, Saturated, Process and long-chain-fatty-acid-CoA ligase activity. Lignoceric acid often locates in Membrane, Microsomes, Plasma membrane, peroxisome and Mitochondria. The associated genes with Lignoceric acid are SLC27A1 gene, CD36 gene, F10 gene, INHA gene and ABCD1 gene. The related lipids are Sphingolipids, Fatty Acids, erucic acid, inositolphosphoceramides and Palmitates.

Cross Reference

Introduction

To understand associated biological information of Lignoceric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Lignoceric acid?

Lignoceric acid is suspected in Peroxisomal Disorders, Adrenoleukodystrophy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lignoceric acid

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Diffuse Cerebral Sclerosis of Schilder D002549 8 associated lipids
Refsum Disease D012035 19 associated lipids
Hyperthyroidism D006980 12 associated lipids
Chondrodysplasia Punctata D002806 8 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Lignoceric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Lignoceric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Lignoceric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Lignoceric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Lignoceric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Lignoceric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Lignoceric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Hashimoto F et al. Effect of gemfibrozil on lipid biosynthesis from acetyl-CoA derived from peroxisomal beta-oxidation. 1995 Biochem. Pharmacol. pmid:7763302
Lageweg W and Wanders RJ Studies on the effect of fenoprofen on the activation and oxidation of long chain and very long chain fatty acids in hepatocytes and subcellular fractions from rat liver. 1993 Biochem. Pharmacol. pmid:8347139
Crook SJ et al. Factors affecting surface expression of glycolipids: influence of lipid environment and ceramide composition on antibody recognition of cerebroside sulfate in liposomes. 1986 Biochemistry pmid:3801428
Lu D et al. Effect of glycosphingolipid fatty acid chain length on behavior in unsaturated phosphatidylcholine bilayers: a 2H NMR study. 1993 Biochemistry pmid:8418849
Uda M et al. Glutamate formed from lignoceric acid by rat brain preparation in the presence of pyridine nucleotide and cytosolic factors: a brain-specific oxidation of very long chain fatty acids. 1981 Biochemistry pmid:7225329
Veerkamp JH and van Moerkerk HT Peroxisomal fatty acid oxidation in rat and human tissues. Effect of nutritional state, clofibrate treatment and postnatal development in the rat. 1986 Biochim. Biophys. Acta pmid:3942767
Vargas CR et al. Evidence that oxidative stress is increased in patients with X-linked adrenoleukodystrophy. 2004 Biochim. Biophys. Acta pmid:14732478
Singh I et al. Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain. 1993 Biochim. Biophys. Acta pmid:8399326
Gulati S et al. Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney. 1993 Biochim. Biophys. Acta pmid:8399363
Reubsaet FA et al. Immunochemical and biochemical studies of fatty acid oxidation in fibroblasts of Zellweger and X-linked adrenoleukodystrophy patients. 1991 Biochim. Biophys. Acta pmid:2049396